Efficacy of salmeterol and magnesium isoglycyrrhizinate combination treatment in rats with chronic obstructive pulmonary disease Research Published on 2022-07-192022-10-05 Journal: Scientific Reports [Category] 바이오마커, 치료제, [키워드] Adverse reaction airway Anti-inflammatory Bronchoalveolar lavage fluid characterized chronic inflammation chronic obstructive Clinical treatment Combination combination treatment contributing to COPD glucocorticoid Hormones IL-1β IL-6 infiltration inflammatory cell involved JAK/STAT signaling pathway Lung function Lung inflammation Lymphocytes Magnesium isoglycyrrhizinate mechanism MUC5AC neutrophil Patient propionate pulmonary disease receptor reduced salmeterol xinafoate secretion serum steroidal anti-inflammatory drugs suggested TNF-α Treatment White blood cells [DOI] 10.1038/s41598-022-16775-2 [Article Type] Research
Immune response and safety to inactivated COVID-19 vaccine: a comparison between people living with HIV and HIV-naive individuals비활성화된 COVID-19 백신에 대한 면역 반응 및 안전성: HIV 감염자와 HIV 감염 경험이 없는 개인 간의 비교Article Published on 2022-07-052022-09-12 Journal: AIDS Research and Therapy [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% CI Adults Adverse reaction Antibody neutralization Antiretroviral therapy baseline binding antibody unit Biological CD4 chemiluminescence colloidal gold COVID-19 COVID-19 vaccine COVID-19 vaccines effective Efficacy ELISA enrolled Follow-up Frequency geometric geometric mean concentration GMC humoral immune response IgG IgG antibody IgG response immune immune response inactivated Inactivated COVID-19 vaccine individual injection NAb not different observation outcome peaked PLWH PLWH population PLWH. primary immunogenicity product remained response SARS-CoV-2 neutralizing antibody second dose Serious Adverse Events seroconversion rate shown Sinopharm specific IgM with HIV Wuhan [DOI] 10.1186/s12981-022-00459-y PMC 바로가기 [Article Type] Article
Safety, Effectiveness, and Immunogenicity 6 Months After BNT162B2 mRNA Vaccine in Frail Nursing Home ResidentsObservational Study Published on 2022-07-012022-10-04 Journal: Drugs & aging [Category] Coronavirus, COVID19(2023년), SARS, 임상, [키워드] acute respiratory syndrome Adverse drug reaction adverse events Adverse reaction age association Binary logistic regression Care Characteristics clinical cognitive collected Comorbidity coronavirus coronavirus disease COVID-19 COVID-19 infection effective Effectiveness elderly evaluate evaluated fatigue female frailty functional headache home Hospital admissions immunogenicity incidence index Loss Month Mortality MOST mRNA mRNA vaccine Nursing Occurrence Older age Palliative care participant pathology percentage positive serology Pyrexia resident Safety SARS-CoV-2 SARS-COV-2 infection scale serious adverse reaction severity Spain vaccination Vaccine was tested [DOI] 10.1007/s40266-022-00959-6 PMC 바로가기 [Article Type] Observational Study
COVID-19 vaccine waning and effectiveness and side-effects of boosters: a prospective community study from the ZOE COVID StudyCOVID-19 백신 약화 및 부스터의 효과 및 부작용: ZOE COVID 연구의 전향적 커뮤니티 연구Article Published on 2022-07-012022-09-11 Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Adverse reaction Adverse reactions Alpha Analysis B.1.1.7 BNT162b2 booster booster dose booster doses ChAdOx1 ChAdOx1 nCoV-19 chronic chronic disease Community community setting Comorbidities completion confounder confounders Control country COVID COVID-19 COVID-19 vaccine dose effective Effectiveness fatigue foundation group Heterologous heterologous schedule heterologous schedules homologous schedule individual Infection investigated Local local symptom Medical Research Council mRNA mRNA-1273 mRNA1273 nCoV new SARS-CoV-2 Odds ratio Older participant Participants Pfizer-BioNTech Poisson regression model positive reactogenicity receiving regimens remained reported SARS-CoV-2 SARS-CoV-2 positivity SARS-CoV-2 test second dose self-reported systemic Side-effect Side-effects Symptom systemic systemic side-effect Systemic side-effects systemic symptom tenderness test result tested those with comorbidities vaccinated individual vaccinated individuals vaccination Vaccine vaccine dose variant variants waned Wellcome Trust [DOI] 10.1016/S1473-3099(22)00146-3 PMC 바로가기 [Article Type] Article
Neuropsychiatric manifestation of the drugs used in the treatment of SARS-2-CoV-2019 (COVID-19) infection and their management: An overview and practice implicationsSARS-2-CoV-2019(COVID-19) 감염 치료에 사용되는 약물의 신경정신병적 발현 및 그 관리: 개요 및 실행 의미Review Published on 2022-07-012022-09-11 Journal: Asian journal of psychiatry [Category] COVID19(2023년), SARS, 변종, 치료법, 치료제, [키워드] Adverse adverse effect Adverse reaction Affect Anti-COVID-19 medications complicate complications consequence COVID COVID-19 COVID-19 treatment dose drug drug-drug interaction drugs hcp Healthcare professional healthcare professionals help highlight implication Infection lAbel management manifestation medication medications myriad Neuropsychiatric off-label off-label use physical Primary infection Prognosis review risk factor Risk factors SARS-2-CoV-2019. Symptom Symptoms Topic Treatment treatment guideline treatment guidelines variant virulence virus [DOI] 10.1016/j.ajp.2022.103101 PMC 바로가기 [Article Type] Review
Safety and Immunogenicity of SARS-CoV-2 Vaccines in Patients With Chronic Liver Diseases (CHESS-NMCID 2101): A Multicenter Study만성 간 질환 환자에서 SARS-CoV-2 백신의 안전성 및 면역원성(CHESS-NMCID 2101): 다기관 연구Multicenter Study Published on 2022-07-012022-09-12 Journal: Clinical gastroenterology and hepatology : the off [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome adverse event Adverse reaction Alanine All participant China chronic chronic liver disease Chronic Liver Diseases cirrhosis CLD collected compensated coronavirus defined dose enrolled healthy healthy control healthy volunteer healthy volunteers immunogenicity immunologic response inactivated injection site pain Laboratory testing limit Mild MOST multicenter study Open-label participant Patient positive rate reported Safe Safety SARS-CoV-2 SARS-CoV-2 neutralizing antibody SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 vaccines second dose serum sample subgroups subject tested Vaccine were recorded whole-virion SARS-CoV-2 vaccine [DOI] 10.1016/j.cgh.2021.12.022 PMC 바로가기 [Article Type] Multicenter Study
Immune response and reactogenicity after immunization with two-doses of an experimental COVID-19 vaccine (CVnCOV) followed by a third-fourth shot with a standard mRNA vaccine (BNT162b2): RescueVacs multicenter cohort studyResearch article Published on 2022-07-012022-10-05 Journal: EClinicalMedicine [Category] 변종, [키워드] Adverse reaction analysed analyses anti-RBD Anti-RBD antibody antibodies antibody benefit Beta BNT162b2 Boost doses of vaccines clinical trial cohort study control group COVID-19 COVID-19 vaccine COVID-19 vaccines CVnCoV Delta development dose elicit European Evidence Experimental vaccines finding fourth dose funding headache heterologous vaccination immune response immunization immunized immunogenic individual IQR local pain median MOST mRNA vaccine mRNA vaccines mRNA-1273 multicenter cohort study multicentre myalgia National neutralising Neutralizing antibodies of BNT162b2 omicron participant participated reactogenicity regimens Regional reported selected severe AE Spanish subject titre vaccination vaccination schedule Vaccine variant were excluded [DOI] 10.1016/j.eclinm.2022.101542 [Article Type] Research article
Efficacy and Safety of Lianhua Qingwen for Patients with COVID-19: A Systematic Review and Meta-AnalysisCovid-19 환자를위한 Lianhua Qingwen의 효능 및 안전성 : 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-07-012022-08-31 Journal: Chinese journal of integrative medicine [Category] 치료제, [키워드] 2019-nCoV Adverse reaction Analysis China Chinese Chinese medicine Computed tomography conducted control group Corona virus cough COVID-19 Data analysis database disease drug effective Efficacy and safety evaluate expectoration experimental group Express fatigue Fever followed by Intervention lianhua qingwen measure Meta-analysis nCoV outbreak outcome measures participant Randomized controlled trial Randomized controlled trials RCT RCTs researchers respiratory Retrospective study review risk of bia Safety scale Shortness of breath Spread subgroup analysis Symptoms systematic review treat treating COVID-19 treating COVID-19 patient Treatment treatment methods Trial trials Virus Disease was used were assessed with COVID-19 [DOI] 10.1007/s11655-022-3578-8 PMC 바로가기 [Article Type] Meta-Analysis
Adverse reactions to the first and second doses of Pfizer-BioNTech COVID-19 vaccine among healthcare workersArticle Published on 2022-07-012023-07-08 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), [키워드] Adverse reaction Age group COVID-19 healthcare worker mRNA vaccine public health SARS-CoV2 Sex [DOI] 10.1016/j.jiac.2022.03.015 PMC 바로가기
Variant of Concern-Matched COVID-19 Convalescent Plasma Usage in Seronegative Hospitalized Patients혈청 음성 입원 환자에서 우려 일치 COVID-19 회복기 혈장 사용의 변형Article Published on 2022-06-302022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] 28-day mortality advanced disease Adverse reaction Adverse reactions affecting age anti-spike monoclonal antibodies anti-spike monoclonal antibody Anti-viral therapy Blood donors CCP collected convalescent convalescent plasma COVID-19 COVID-19 convalescent plasma Delta Efficacy hospital Hospitalized hospitalized COVID-19 patient hospitalized patient Immunocompromised Immunocompromised patient Immunocompromised patients infused IQR Italian mAb mAbs median age mortality rate NAbs Neutralizing antibodies neutralizing antibody omicron outcome patients protective immune response Randomized controlled trial recipient reported rescued SARS-CoV-2 seronegative severe COVID-19 Support Two patient two patients Usage variants variants of concern VoC VOCs were recorded [DOI] 10.3390/v14071443 PMC 바로가기 [Article Type] Article