Mice Immunized with the Vaccine Candidate HexaPro Spike Produce Neutralizing Antibodies against SARS-CoV-2Communication Published on 2021-05-122022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] aluminum Antigen candidate collected comparable COVID-19 vaccine equity feasibility Genetic variation HexaPro high-titer neutralizing antibody hydroxide immunization immunized Infection initial live SARS-CoV-2 mice neutralization activity offer physical prefusion prime-boost regimen Produce produced raising RBD receiving recombinant reported S-2P Safe SARS-CoV-2 sera shown spike spike trimer spike trimers subunit Subunit vaccine the receptor-binding domain the SARS-CoV-2 the spike protein Vaccine [DOI] 10.3390/vaccines9050498 PMC 바로가기 [Article Type] Communication
CpG-adjuvanted stable prefusion SARS-CoV-2 spike protein protected hamsters from SARS-CoV-2 challengeSARS-CoV-2 공격으로부터 햄스터를 보호하는 CpG 보조 안정 예비 융합 SARS-CoV-2 스파이크 단백질Article Published on 2021-04-222022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료기술, [키워드] alum aluminum aluminum hydroxide applied average build clinical development comparable control groups COVID-19 pandemic COVID-19 vaccine CpG Detection limit Diseases dose effective vaccine global public health group hamster hydroxide IgG immunized immunogenic immunogenicity immunology imperative Infection injection intramuscularly intranasally Lung pathology lung viral load Microbiology Neutralizing antibodies neutralizing antibody Neutralizing titer pandemic prefusion produced Protective pseudovirus Rapid reduced S-2P Safe SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike protein significantly Support the vaccine titers Vaccine vehicle Viral virus weight loss with infection [DOI] 10.1038/s41598-021-88283-8 PMC 바로가기 [Article Type] Article
Th1 skewed immune response of whole virion inactivated SARS CoV 2 vaccine and its safety evaluationArticle Published on 2021-03-102022-10-30 Journal: iScience [Category] COVID-19, [키워드] Abstract adjuvants agonist aluminum animal model Antibody Response Antigen BSL-3 facility carried CD4 clinical trial Concentration concentrations elevated gel humans hydroxide IFN-γ immune response Immunity immunogenicity immunology inactivated Inactivated vaccine mice Microbiology NAb titer Neutralizing antibody titer platform product profiles purified response robust Safe SARS CoV SARS-CoV-2 strain SARS-CoV-2 vaccine significantly skewed Support T lymphocyte response Th1 TLR7/8 Vaccine Vero Cell virion Virology [DOI] 10.1016/j.isci.2021.102298 PMC 바로가기 [Article Type] Article
Comparing analytical methods to detect SARS-CoV-2 in wastewater폐수 내 SARS-CoV-2 검출을 위한 분석 방법 비교Article Published on 2021-03-012022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, 치료제, [키워드] aluminum Aluminum-based adsorption-precipitation applied automated centrifugation Concentration coronavirus disease Coronavirus disease 2019 COVID-19 detect diarrhea Efficiency epidemic diarrhea Epidemiology evaluated FIVE Genome genomic glycol inactivated limits log mengovirus pandemic PEDV Polyethylene glycol Polyethylene glycol precipitation Porcine epidemic diarrhea virus precipitation method protocol ranged recent RNA extraction RT-qPCR SARS-CoV-2 SARS-CoV-2 detection sensitivity significant difference significant differences silica Surrogates Surveillance target urban virus was used wastewater wastewater based epidemiology [DOI] 10.1016/j.scitotenv.2020.143870 PMC 바로가기 [Article Type] Article
Evaluation of viral concentration methods for SARS-CoV-2 recovery from wastewaters폐수로부터 SARS-CoV-2 회수를 위한 바이러스 농도 방법 평가Article Published on 2021-02-202022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, [키워드] alarm system aluminum Analysis approach calicivirus Community complementary Concentration COVID-19 COVID-19 infection COVID-19 infections COVID-19 outbreak COVID-19 surveillance Critical Efficiency Epidemiology evaluate followed by glycol handling highlight IMPROVE limit of detection membrane methodological methodology MONITOR option Polyethylene glycol protocol protocols provide reported risk SARS-CoV-2 sensitivity sewage Surveillance tested Ultrafiltration viability Viral Viral concentration methods virus viruses was used wastewater Wastewater-based epidemiology [DOI] 10.1016/j.scitotenv.2020.144105 PMC 바로가기 [Article Type] Article
Influence of aluminum salts on COVID-19 infected patientsCOVID-19 감염 환자에 대한 알루미늄 염의 영향Observational Study Published on 2020-12-172022-09-10 Journal: Turkish Journal of Medical Sciences [Category] MERS, SARS, 임상, 치료제, [키워드] addition alum aluminum aluminum salts Analysis Antiviral Chain Reaction clinical Clinical findings Comorbidity Control control group Coronavirus (COVID-19) COVID-19 COVID-19 infected patient COVID-19 infected patients CRP level CRP levels diagnosed discharge drop Effect examined Follow-up group Hospital stay Hospitalization include infected cases infected patients Infectious disease influence intake intensive care Laboratory parameters Lactate lactate dehydrogenase LDH material mechanical ventilation not achieved oral intake pandemic patients PCR performed Pneumonia polymerase chain polymerase chain reaction procalcitonin procalcitonin level radiological Recovery time recovery times Result retrospective cohort study salt salts Side effect Side effects significantly significantly shorter survival Symptom Symptoms the patient Toxicity Treatment treatment group Treatment protocol treatment protocols two group two groups [DOI] 10.3906/sag-2009-140 PMC 바로가기 [Article Type] Observational Study
Impact of catch-up vaccination on aluminum exposure due to new laws and post social distancingArticle Published on 2020-12-012023-07-13 Journal: Journal of trace elements in medicine and biology [Category] SARS, [키워드] aluminum COVID-19 vaccination Vaccines [DOI] 10.1016/j.jtemb.2020.126649 PMC 바로가기
Development of CpG-adjuvanted stable prefusion SARS-CoV-2 spike antigen as a subunit vaccine against COVID-19Article Published on 2020-11-182022-10-04 Journal: Scientific Reports [Category] 변종, 치료기술, [키워드] addition Administered adverse effect aluminum applied candidate vaccine Combination COVID-19 COVID-19 disease COVID-19 pandemic COVID-19 vaccine CpG cross-neutralize cytokine D614G variant development dominant elicited ENhance health emergency hydroxide immunized immunized mice immunology immunopathology lentivirus MERS-CoV mice Microbiology mitigate neutralizing antibody prefusion Prevent pseudotyped pseudovirus reporter S-2P SARS-CoV-2 spike antigen SARS-CoV-2 spike protein secreted sera splenocyte subunit Support Th1 the antibody the spike protein TLR9 Toll-like receptor Treatment two-dose regimen Vaccine was selected wild-type SARS-CoV-2 [DOI] 10.1038/s41598-020-77077-z PMC 바로가기 [Article Type] Article
Adjuvants for Coronavirus VaccinesImmunology Published on 2020-11-062022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] adjuvant adjuvants aluminum aluminum salt assist component coronavirus coronavirus disease Coronavirus disease 2019 coronavirus vaccine Coronavirus vaccines COVID-19 COVID-19 vaccines Critical Effect Efficacy and safety Evidence immune response Inactivated vaccine induce lack long-lasting MERS-CoV Middle East pandemic platform profile reported robust SARS-CoV SARS-CoV-2 subunit tested the SARS-CoV-2 TLR agonists Vaccine [DOI] 10.3389/fimmu.2020.589833 PMC 바로가기 [Article Type] Immunology
Fractured aluminum nasopharyngeal swab during drive-through testing for COVID-19: radiographic detection of a retained foreign bodyCase Reports Published on 2020-11-012023-07-12 Journal: Skeletal Radiology [Category] SARS, [키워드] aluminum COVID-19 foreign body Nasopharyngeal swab Radiographs X-ray [DOI] 10.1007/s00256-020-03582-x PMC 바로가기 [Article Type] Case Reports