Recurrence of COVID-19 associated with reduced T-cell responses in a monozygotic twin pairResearch Published on 2022-02-022022-10-29 Journal: Open Biology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] acute respiratory distress avoidance binding Complete coronavirus COVID-19 Diseases effective IFN immune mechanism immune response Immunity increasingly individual Infection initial interferon investigated involved lack monozygotic twin NAb neutralizing antibody presenting recovered patient recurrence reduced reported SARS-CoV-2 severe acute respiratory distress syndrome coronavirus 2 syndrome T cell T-cell T-cell epitope T-cell Response twin twins viral control [DOI] 10.1098/rsob.210240 PMC 바로가기 [Article Type] Research
SARS-CoV-2 spike S1 subunit induces neuroinflammatory, microglial and behavioral sickness responses: Evidence of PAMP-like propertiesSARS-CoV-2 스파이크 S1 소단위체는 신경염증, 소교세포 및 행동병 반응을 유도합니다: PAMP 유사 특성의 증거Article Published on 2022-02-012022-09-11 Journal: Brain, behavior, and immunity [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] activated Activation Anxiety avoidance Brain brain region brain regions CAGE CD11b CD200R1 cells characterized CNS cognitive CXCL1 cytokine signaling demonstrated Depression Direct direct viral infection Evidence evidence of examined function Gene Expression GFAp HEK293 HEK293 cells HMGB1 Hypothesis IFNγ IL-10 IL-1β IL-2 IL-6 IL1B in vitro include independent independent of induce Infection Inflammatory injected male mechanism MHCII microglia microglial modulated Neuroinflammation neurological Neuropsychiatric NLRP3 PAMP PAMPs pathogen pathogen-associated molecular Pattern recognition pattern recognition receptor Protein protein level protein levels receptor signaling reduced S1 subunit SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 spike protein Sickness Sickness behavior spike Spike protein structural protein structural proteins Symptom the S1 subunit the SARS-CoV-2 TLR TLR. TLR2 TLR4 TNF transgenic Treatment vehicle viral infection [DOI] 10.1016/j.bbi.2021.12.007 PMC 바로가기 [Article Type] Article
The substitution spectra of coronavirus genomes코로나 바이러스 게놈의 치환 스펙트럼Problem Solving Protocol Published on 2022-01-132022-09-10 Journal: Briefings in Bioinformatics [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect animal coronavirus Animal coronaviruses Apolipoprotein B avoidance can not catalytic change Complete coronavirus coronavirus genome CpG decrease determined by dinucleotide effort eliminated Evidence evidence of expected Factors Frequency Host hosts Increases information International intrinsic Middle East Middle East respiratory syndrome Middle East respiratory syndrome Coronavirus mRNA Mutation nucleotide pandemic positive-sense proportion proportions Protein reduction Replication respiratory respiratory syndrome coronavirus RNA viruses SARS-CoV-2 SARS-CoV-2 pandemic selective sequence severe acute respiratory syndrome Coronavirus Spread Substitution substitutions transitions transversions triggered Viral viral genomes [DOI] 10.1093/bib/bbab382 PMC 바로가기 [Article Type] Problem Solving Protocol
Self-Reported Dietary Choices and Oral Health Care Needs during COVID-19 Quarantine: A Cross-Sectional StudyArticle Published on 2022-01-132022-10-31 Journal: Nutrients [Category] COVID-19, SARS, [키워드] affected age avoidance BMI Care change choice conducted COVID-19 COVID-19 pandemic COVID-19/SARS-CoV-2 cross-contamination cross-sectional demonstrated dietary Dietary changes dietary habits dropped Effect fear female gingivitis Health health care need Healthcare system highlight highlighting hygiene impacted Measures oral oral epidemiology oral health overweight pandemic Poland public dentistry questionnaire Responder significantly subjects tooth [DOI] 10.3390/nu14020313 PMC 바로가기 [Article Type] Article
Gender Differences in Psychological Stress Factors of Physical Therapy Degree Students in the COVID-19 Pandemic: A Cross-Sectional StudyArticle Published on 2022-01-122022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] acceptance Action Anxiety avoidance Beck conducted COVID-19 COVID-19 pandemic cross-sectional degree Depression difference domain Effect European evaluated Factor female form Health impacted inventory item knowledge loneliness male males mental health mitigate participant Perceived Stress Scale physical physical therapy students preventive program Psychological psychological Impact Psychological intervention Quality Quality of life scale Sleep sleep quality Spanish Stress student Support survey Symptoms therapy university [DOI] 10.3390/ijerph19020810 PMC 바로가기 [Article Type] Article
COVID-19-Related Psychological Trauma and Psychological Distress Among Community-Dwelling Psychiatric Patients: People Struck by Depression and Sleep Disorders Endure the Greatest BurdenPublic Health Published on 2022-01-072022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] age age/unemployment/single/marital status Arabic/Arab/Saudi Arabia avoidance burden Care consequence coronavirus disease 2019/COVID-19 COVID-19 cross-sectional DASS-21 Depression diagnosed disorder disorders distress drug expressed group Health IES-R Impact implication information Intervention likelihood major depression disorder/sleep disorders measure Measures mental health pandemic Patient Perceived physical predicted predictor Protective Psychiatric psychiatric diagnoses psychiatric disorder psychiatric disorders/co-morbid physical disorders Psychological distress Psychological trauma quarantine questionnaire reported respondent Satisfaction significant difference Sleep sleep disorder sleep disorders socio-demographic information stay-at-home Stress Scale Struck by suffered Symptom trauma Vaccines with COVID-19 [DOI] 10.3389/fpubh.2021.799812 PMC 바로가기 [Article Type] Public Health
A Population-Based Analysis of Diabetes-Related Care Measures, Foot Complications, and Amputation During the COVID-19 Pandemic in Ontario, CanadaResearch Published on 2022-01-052022-10-29 Journal: JAMA Network Open [Category] Coronavirus, [키워드] 95% CI age amputation association avoidance calculated Canada Care cohort study Comorbidity Complication complications Comprehensive contributed COVID-19 COVID-19 pandemic declined demographic characteristics diabete diabetes Diabetic dropped evaluate finding foot hemoglobin hospital Hospitalization Importance increase in limb maintain measure Measures median men objective outcome pandemic participant Patient Physicians Point population-based cohort positive Rate rate ratio Relevance remained Result RRs selected setting study period Treatment [DOI] 10.1001/jamanetworkopen.2021.42354 PMC 바로가기 [Article Type] Research
Risk perception and behaviour during the COVID-19 pandemic: Predicting variables of compliance with lockdown measuresResearch Article Published on 2022-01-052022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] Administered aversion avoidance behavioural character cognitive Compliance Control COVID-19 COVID-19 pandemic dimension driving Evidence Factor foundation Government Health help inherent Intention Intervention Italy joint lockdown locus measure Measures modulated modulating Moral National precautionary behaviours predict predicted promote Psychological questionnaire regressions risk temperament variable Variation [DOI] 10.1371/journal.pone.0262319 PMC 바로가기 [Article Type] Research Article
A real-world study of immune thrombocytopenia management during the COVID-19 pandemic in the UK영국에서 COVID-19 전염병 동안 면역 혈소판 감소증 관리에 대한 실제 연구Observational Study Published on 2022-01-012022-09-12 Journal: British Journal of Haematology [Category] MERS, 임상, 진단, [키워드] avoidance coronavirus disease Coronavirus disease 2019 COVID COVID-19 infection COVID-19 pandemic COVID-19 vaccination diagnosed effective England hospital immune Immune thrombocytopenia Immune thrombocytopenic purpura investigated management NHS outcome Patient Platelets Prospective Study steroid submitted supported thought thrombocytopenia Treatment WHO [DOI] 10.1111/bjh.17804 PMC 바로가기 [Article Type] Observational Study
Acceptability of the COVID-19 Vaccine among Adults in Saudi Arabia: A Cross-Sectional Study of the General Population in the Southern Region of Saudi ArabiaArticle Published on 2021-12-292022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acceptability analysed avoidance collected COVID-19 COVID-19 vaccination COVID-19 vaccine cross-sectional survey determinant determine Diseases effective Evidence General population Healthcare system immunisation majority participant Perceived risk Population practitioners predictor prevalence of COVID-19 PROTECT questionnaire receive reducing Region Safe Saudi Arabia Seasonal influenza SPSS the vaccine vaccination Vaccinations Vaccine Vaccine acceptance Vaccine hesitancy [DOI] 10.3390/vaccines10010041 PMC 바로가기 [Article Type] Article