A Phenome-Wide Association Study (PheWAS) of COVID-19 Outcomes by Race Using the Electronic Health Records Data in Michigan MedicineArticle Published on 2021-03-252022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] association Biobank Circulatory clinical diagnose condition Coronavirus disease 2019 COVID-19 disease EHR Health disparities healthcare hematopoietic Hospitalization ICU identify IMPROVE intensive care Medicine Mental disorder Mortality Odds ratio outcome Patient performed phenome Population Prognosis race Record renal Respiratory failure risk profile Support understanding [DOI] 10.3390/jcm10071351 PMC 바로가기 [Article Type] Article
Association between socioeconomic status and self-reported, tested and diagnosed COVID-19 status during the first wave in the Northern Netherlands: a general population-based cohort from 49 474 adults사회경제적 지위와 북부 네덜란드의 첫 번째 물결 동안 COVID-19 자가 보고, 테스트 및 진단 상태 간의 연관성: 성인 49,474명의 일반 인구 기반 코호트Epidemiology Published on 2021-03-222022-09-01 Journal: BMJ Open [Category] 진단, [키워드] age alcohol association Biobank body mass body mass index clinical setting clinical settings cohort study COVID-19 COVID-19 infection diagnosed Epidemiology Ethnicity Factor Factors First wave General population groups investigated less men and women Netherland objective outcome measure outcome measures participant physical activity population-based cohort positive public health questionnaire Result Sex sleep time smoking status socioeconomic status study population tested vulnerable population was obtained were assessed with COVID-19 [DOI] 10.1136/bmjopen-2020-048020 PMC 바로가기 [Article Type] Epidemiology
SARS-CoV-2-Specific Memory T Lymphocytes From COVID-19 Convalescent Donors: Identification, Biobanking, and Large-Scale Production for Adoptive Cell TherapyCell and Developmental Biology Published on 2021-02-252022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] absence adoptive cell therapy (ACT) adverse effect Biobank Blood CD3 CD4 CD45RA CD8 central memory Complete convalescent coronavirus COVID-19 develop disease Donor donors effective Effective vaccines effector memory feasible GMP hospitalized patient identification immune protection Infection lymphopenia memory T cell memory T cells (Tmem) outbreak pandemic pathogen patients patients hospitalized Production reduce respond SARS-CoV-2 SARS-CoV-2-specific T cell Secondary infection severity of COVID-19 significantly subpopulations subset Symptoms therapeutic option these cell treat Treatment with COVID-19 [DOI] 10.3389/fcell.2021.620730 PMC 바로가기 [Article Type] Cell and Developmental Biology
Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patientsArticle Published on 2021-02-052022-10-04 Journal: Scientific Reports [Category] MERS, 바이오마커, 치료기술, [키워드] Admission adverse outcome age Analysis Biobank body mass index calculator Cohort common Computational science COVID-19 Curve death Denmark Developing Diagnosis Disease progression driver European external validation feature Healthcare system hospital Hospital admission hypertension ICU ICU admission ICU Patients identify indicated Infectious diseases intensive care unit management marker mechanical ventilation Metrics ML model Mortality operation organ dysfunction Patient patients with COVID-19 performed positive Positive test predict predicted Predictive Prognostic marker progression receiver risk Risk factors risk of death SARS-CoV-2 SARS-CoV-2 PCR test severe COVID-19 severe disease Shock Stage subject United Kingdom was used [DOI] 10.1038/s41598-021-81844-x PMC 바로가기 [Article Type] Article
Host genetic effects in pneumonia폐렴의 숙주 유전적 영향Article Published on 2021-01-072022-09-11 Journal: American Journal of Human Genetics [Category] 변종, [키워드] African association Biobank Cell CFTR conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 hospitalization cystic fibrosis diagnosed disease disease susceptibility Diseases downstream Effect Electronic health record Electronic health records European fibrosis Genetic Genome-wide association study genotyped GWAS GWASs HBB Health health record highlight Host host genetic effect host genome host susceptibility hypoxia Illumina independent individual individuals Infectious disease Infectious diseases lead locus Lung disease Lung function offer p value pandemic performed Pneumonia R3HCC1L Region replicated Respiratory failure rs334 SCD severity severity of COVID-19 sickle cell Sickle cell disease subjects susceptibility UK biobank university variant variants [DOI] 10.1016/j.ajhg.2020.12.010 PMC 바로가기 [Article Type] Article
Growth Differentiation Factor 15 Provides Prognostic Information Superior to Established Cardiovascular and Inflammatory Biomarkers in Unselected Patients Hospitalized With COVID-19성장 분화 인자 15는 COVID-19로 입원한 선택되지 않은 환자에서 확립된 심혈관 및 염증성 바이오마커보다 우수한 예후 정보를 제공합니다Article Published on 2020-12-012022-08-31 Journal: Circulation [Category] MERS, SARS, 바이오마커, 치료기술, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus Admission age association Atrial fibrillation baseline Biobank Biomarkers body mass body mass index C-reactive protein cardiac troponin cardiac troponin T cardiovascular cardiovascular disease collected Concentration coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 CVD D-dimer death detectable diabetes differentiation elevated enrolled estimated glomerular filtration rate Factor ferritin filtration rate glomerular filtration rate greater growth growth differentiation factor 15 healthy individuals heart failure Hospitalization hospitalized patient hospitalized patients Hypoxemia increase Infection Infectious disease inflammatory biomarkers intensive care intensive care unit interleukin interleukin-6 laboratory-confirmed lower oxygen saturation majority median Myocardial infarction N-terminal N-terminal pro-B-type natriuretic peptide Older outcome oxygen Patient patients hospitalized peptide primary end point pro-B-type natriuretic peptide procalcitonin prognostic Prognostic marker Prognostic value reached Registration respiratory risk SARS-CoV-2 score Sepsis severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Sex Superior symptoms of COVID-19 troponin T Viremia with COVID-19 [DOI] 10.1161/CIRCULATIONAHA.120.050360 PMC 바로가기 [Article Type] Article
Opportunities and Risks for Research Biobanks in the COVID-19 Era and BeyondReview Published on 2020-12-012023-07-05 Journal: Biopreservation and biobanking [Category] SARS, [키워드] Best practices Biobank COVID-19 Laboratory safety opportunities and risks sustainability [DOI] 10.1089/bio.2020.0079 PMC 바로가기 [Article Type] Review
Biobanking in the COVID-19 Era and Beyond: Part 1. How Early Experiences Can Translate into Actionable WisdomArticle Published on 2020-12-012023-07-11 Journal: Biopreservation and biobanking [Category] SARS, [키워드] Best practices Biobank COVID-19 Standards survey tools [DOI] 10.1089/bio.2020.0082
Establishment of a Collection of Blood-Derived Products from COVID-19 Patients for Translational Research: Experience of the LPCE Biobank (Nice, France)Article Published on 2020-12-012023-07-12 Journal: Biopreservation and biobanking [Category] SARS, [키워드] Biobank Blood COVID-19 Research SARS-CoV-2 [DOI] 10.1089/bio.2020.0055
The Responses of Biobanks to COVID-19Article Published on 2020-12-012023-07-13 Journal: Biopreservation and biobanking [Category] SARS, [키워드] Biobank COVID-19 Pandemic response [DOI] 10.1089/bio.2020.29074.mkh PMC 바로가기