both viruses – Page 4 – Communicable Diseases Research

SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patients

SARS-CoV-2 성장, 퓨린 절단 부위 적응 및 급성 감염 입원 COVID-19 환자의 혈청을 사용한 중화

Research Article

Published on 2020-11-212022-09-10
Journal: The Journal of General Virology [Category] MERS, SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adaptation angiotensin antigenic target Betacoronavirus both viruses causative agent caused Cell cell lysate cell surface cells characterized cleavage clinical isolates comparable coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 deaths deleted Deletion demonstrated disease expand furin furin cleavage generate glycoprotein growth hACE2 Healthcare system Healthcare systems hospitalized COVID-19 patient host range human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 in vitro in vivo indirect immunofluorescence inefficient Infection insertion investigated Like MinION Munich neutralization Neutralizing antibodies neutralizing antibody titre neutralizing antibody titres Pathogenesis patients reached receptor respiratory S glycoprotein S protein SARS-CoV SARS-CoV-2 SARS-CoV-2 spike Sequencing serum serum sample severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spread to strain the cell the S protein the SARS-CoV-2 variant Vero E6 Vero E6 cell VERO E6 cells virus virus stock virus stocks viruses
[DOI] 10.1099/jgv.0.001481 PMC 바로가기 [Article Type] Research Article

No Evidence of SARS-CoV-2 Circulation in Rome (Italy) during the Pre-Pandemic Period: Results of a Retrospective Surveillance

Article

Published on 2020-11-162022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, SARS,

[키워드] acute respiratory syndrome affected both viruses characterized collected coronavirus country COVID-19 COVID-19 outbreak COVID-19 pandemic Critical detectable Diagnostic method epidemiological and etiological surveillance evaluated evidence of health authorities hospital in some infection prevalence Influenza influenza-like syndrome investigated investigator Italian Italy Laboratory Local Nasopharyngeal swab pandemic Patient Pneumonia positive preserved radiological recorded reported Result Rome routine monitoring SARS-CoV-2 SARS-CoV-2 RT-PCR Spread Study protocol syndrome tested the SARS-CoV-2 virus WHO with COVID-19 World Health Organization
[DOI] 10.3390/ijerph17228461 PMC 바로가기 [Article Type] Article

Viral interference between low pathogenic avian influenza H9N2 and avian infectious bronchitis viruses in vitro and in ovo

Article

Published on 2018-06-222022-11-01
Journal: Journal of virological methods [Category] Coronavirus,

[키워드] appear Avian infectious bronchitis disease virus Avian influenza virus both viruses bronchitis CC, cell cultures CEL CEL, chick embryo lung CEL, chicken embryo lung Cell culture cell cultures chicken Co-infection condition conditions cytokine decrease described DMEM, Dulbecco’s modified Eagle’s medium ECE, embryonated chicken eggs EID₅₀, fifty-percent egg infectious dose ELISA ELISA assay evaluate FCS, fetal calf serum Genome growth HA, hemagglutinin IBV IBV, infectious bronchitis virus IL-1 IL-1beta in vitro infections Infectious Bronchitis Virus Influenza inoculated Interaction LPAI, low pathogenic avian influenza lung MEM, minimum essential media p.i., post-infection pathogen pathogenic PBS, phosphate buffered saline real-time RT-PCR Result rRT-PCR, real time RT-PCR RT-PCR secreted SPF, specific pathogen free supernatant TCID₅₀, fifty-percent tissue culture infectious dose vaccine strain viral growth viral interference virus virus growth was determined
[DOI] 10.1016/j.jviromet.2018.06.011 PMC 바로가기 [Article Type] Article

An eight-year epidemiologic study based on baculovirus-expressed type-specific spike proteins for the differentiation of type I and II feline coronavirus infections

Research Article

Published on 2014-08-152022-10-28
Journal: BMC veterinary research [Category] Coronavirus, MERS,

Zn 2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture

Research Article

Published on 2010-11-042022-10-29
Journal: PLoS Pathogens [Category] Coronavirus, MERS,

[키워드] activity Antiviral arteritis arterivirus Author binding block both viruses catalyzed Cell Cell culture Combination complex complexes Concentration described divalent cation E. coli eliminating enzyme equine found function host proteins impair in vitro activity in vitro study include Increased Increasing Infected Influenza virus inhibit inhibited inhibitory effect Ionophore molecular nidovirus Nsp12 Nsp9 Pathogens plasma Poliovirus polymerases polyprotein polyproteins Proteolytic processing protocol provide purified RdRP RdRps reduced related Replication replication complex replicative Research reversed RNA RNA synthesis RNA viruses RNA-dependent RNA polymerase RTC SARS-coronavirus SARS-CoV target Transcription Transport variety Viral RNA virus Zinc Zn
[DOI] 10.1371/journal.ppat.1001176 PMC 바로가기 [Article Type] Research Article