Epidemiological and clinical characteristics of the largest COVID-19 outbreak along the China-Myanmar border in Ruili City, Yunnan Province, ChinaArticle Published on 2022-08-232022-11-16 Journal: Frontiers in Public Health [Category] SARS, 변종, 유전자 메커니즘, [키워드] antibody breakthrough infections caused Characteristics China China-Myanmar border Chinese city Clinical characteristics collected Contact COVID-19 COVID-19 outbreak COVID-19 patient COVID-19 vaccination COVID-19 vaccine cycle threshold death Delta delta variant Epidemics epidemiological greater IgM and IgG immune Infection land mechanism Mild moderate MOST occurred outbreak Patient rapid response reported Research risk SARS-CoV-2 SARS-CoV-2 Delta VOC Sequencing Transmission vaccinated against COVID-19 VoC were used [DOI] 10.3389/fpubh.2022.962214 PMC 바로가기
How I treat and prevent COVID-19 in patients with hematologic malignancies and recipients of cellular therapies혈액암 환자와 세포 요법을 받는 환자의 COVID-19 치료 및 예방 방법Article Published on 2022-08-182022-09-11 Journal: Blood [Category] SARS, 변종, 임상, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration approach attenuate breakthrough infections Cell Cell therapy cell transplantation cellular therapy circulating circulating SARS-CoV-2 variants Clinical efficacy coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 in patient COVID-19 vaccine COVID-19 vaccines Drug-drug interactions Factors General population HCT Hematologic malignancy Hematopoietic cell transplantation higher risk Host Humoral response increased risk Infection morbidity morbidity and mortality Patient Postexposure Prophylaxis practicality Prevent progression recipient recipients SARS-CoV-2 Selection severe acute respiratory syndrome Coronavirus severe coronavirus disease severe COVID-19 Side effects therapeutic Therapies therapy treat Treatment virus [DOI] 10.1182/blood.2022016089 PMC 바로가기 [Article Type] Article
Cellular and humoral immune responses and breakthrough infections after three SARS-CoV-2 mRNA vaccine dosesArticle Published on 2022-08-172022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] adaptive Administered antibody Asymptomatic BNT162b2 Breakthrough infection breakthrough infections cellular Cohort COVID-19 COVID-19 pandemic declined determine dose effective Follow-up healthcare humoral humoral immune response Hybrid immunity IgG immune immune response Immunity Inclusion increase in individual knowledge Longitudinal assessment Mild mRNA vaccine mRNA-1273 naïve naïve individual naïve individuals neutralization neutralizing antibody peak level Prevent reached reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV-2-specific T cells second dose T cell T cells third dose triggered vaccination Vaccine Viral antigen [DOI] 10.3389/fimmu.2022.981350 PMC 바로가기
Association of Frailty, Age, and Biological Sex With Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine-Induced Immunity in Older Adults중증 급성 호흡기 증후군 코로나바이러스 2 메신저 RNA 백신 유도 면역과 노쇠, 연령 및 생물학적 성별의 연관성Article Published on 2022-08-152022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 치료법, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adults age aging antibody Antibody binding Antibody Response Antibody responses Antibody titer binding Biological Breakthrough infection breakthrough infections caused characterized collected coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Coverage declined Delta domain dose eliminated female females frailty functional functional antibody response functional antibody responses greater Intersection male Male sex males messenger mRNA vaccination neutralization nucleocapsid old age Older older adult omicron plasma samples Promoting receipt reduced respiratory response restored risk factor Risk factors RNA SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens second dose severe acute respiratory syndrome Coronavirus severe coronavirus disease Sex sex differences significantly Spike protein the vaccine Vaccine vaccine dose variant variants of concern virus VoC VOCs vulnerable population were measured [DOI] 10.1093/cid/ciac397 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Infectivity and Antibody Titer Reduction for 6 Months After Second Dose of BNT162b2 mRNA Vaccine in Health Care Workers: A Prospective Cohort Study의료 종사자에서 BNT162b2 mRNA 백신 2차 접종 후 6개월 동안 SARS-CoV-2 감염성 및 항체 역가 감소: 전향적 코호트 연구Article Published on 2022-08-122022-09-12 Journal: The Journal of Infectious Diseases [Category] SARS, 진단, [키워드] acute respiratory syndrome antibody antibody formation Antibody titer antibody titer dynamics binding domain blood sample Breakthrough infection breakthrough infections Care coronavirus disease Coronavirus-2 decrease dose enrolled HCW HCWs Health Health care worker health care workers individuals Infection Infectivity Month mRNA mRNA vaccination neutralizing antibody no significant difference of BNT162b2 participant Probability Prospective receiving reduction reported SARS-CoV-2 second second vaccination titer vaccination [DOI] 10.1093/infdis/jiac035 PMC 바로가기 [Article Type] Article
Direct comparison of RT-ddPCR and targeted amplicon sequencing for SARS-CoV-2 mutation monitoring in wastewater폐수에서 SARS-CoV-2 돌연변이 모니터링을 위한 RT-ddPCR과 표적 앰플리콘 시퀀싱의 직접 비교Article Published on 2022-08-102022-09-11 Journal: The Science of the total environment [Category] Coronavirus, COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Amplicon sequencing Analysis analyzed applied approach ARTIC association breakthrough infections characteristic contagious Course Coverage COVID-19 pandemic determined by Direct Epidemiology event FIVE gold gold standard highlighting Mutation mutations over positive quantification quantitative measurement referred to reported RT-ddPCR SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 variant SARS-CoV-2 variants sensitivity Sequencing variants variants of concern variants of concern (VOC) variants of SARS-CoV-2 VOCs wastewater wastewater-based epidemiology (WBE) [DOI] 10.1016/j.scitotenv.2022.155059 PMC 바로가기 [Article Type] Article
COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivationCOVID-19 mRNA 부스터 백신은 일시적인 CD8+ T 효과기 세포 반응을 유도하는 동시에 후속 재활성화를 위해 메모리 풀을 보존합니다Article Published on 2022-08-082022-09-11 Journal: Nature Communications [Category] 변종, 진단, 치료기술, [키워드] activated analyzed boost booster vaccination Booster vaccine Breakthrough infection breakthrough infections CD8 CD8+ Cell conserved COVID-19 COVID-19 vaccination Delta dose effector cell elicit followed by Immunity immunization individual induce memory mRNA mRNA vaccine Neutralizing antibody response neutralizing antibody responses not affected omicron recall receiving response robust stem cell subsequent T cell T cell response T cell responses T cells T memory cells vaccination variants of concern waning immunity [DOI] 10.1038/s41467-022-32324-x PMC 바로가기 [Article Type] Article
COVID-19 and plasma cells: Is there long-lived protection?COVID-19 및 형질 세포: 오래 지속되는 보호 기능이 있습니까?Review Published on 2022-08-012022-09-11 Journal: Immunological reviews [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] antibody antibody secretion antibody-secreting cell B cells Blood Bone marrow Breakthrough infection breakthrough infections Cell contribute COVID-19 COVID-19 pandemic death Effective vaccines etiology focus Hospitalization humoral Immunity immunization Infection knowledge lack long-lived plasma cell long-lived plasma cell. long-lived plasma cells memory memory B cell memory B cells mutant virus Neutralizing antibodies neutralizing antibody occur offer pandemic plasma Plasma cell Plasma cells populations SARS-CoV-2 SARS-COV-2 infection secreting cell severe disease vaccination viruses [DOI] 10.1111/imr.13115 PMC 바로가기 [Article Type] Review
SARS-CoV-2 Delta-variant breakthrough infections in nursing home residents at midterm after Comirnaty® COVID-19 vaccinationComirnaty® COVID-19 백신 접종 후 중간에 요양원 거주자의 SARS-CoV-2 Delta 변이형 돌발 감염Article Published on 2022-08-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus anti-RBD Anti-spike anti-spike antibodies antibody Antibody Response Antibody responses assays Breakthrough infection breakthrough infections Chain Reaction characterized Comirnaty® COVID-19 vaccine Community coronavirus COVID-19 COVID-19 vaccination COVID-19 vaccine Delta delta variant determined by develop diagnosis of SARS-CoV-2 female flow cytometry Frequency Hospitalization infected with SARS-CoV-2 Infection lateral flow lower risk median median age naïve nasopharyngeal specimen nine nursing home nursing home residents nursing homes occurred participant Participants plasma polymerase chain polymerase chain reaction positive prior diagnosis quantified Quantitative respiratory RNA loads SARS-CoV-2 SARS-CoV-2 Delta variant SARS-COV-2 infection SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spain spike-reactive T cells. T cell T cells tested vaccination Valencian [DOI] 10.1002/jmv.27799 PMC 바로가기 [Article Type] Article
Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5SARS-CoV-2 오미크론 하위 변이체 BA.2.12.1, BA.4 및 BA.5에 의한 항체 회피Article Published on 2022-08-012022-09-11 Journal: Nature [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Analysis antibodies antibody antigenic bebtelovimab breakthrough infections Clinical use COVID-19 vaccine COVID-19 vaccines dominant Efficacy evade facilitate individual lead Lineage Mutation Neutralizing antibodies omicron raise receptor Receptor-binding domain Region residue SARS-CoV-2 sera South Africa Spike protein Spike proteins the receptor-binding domain the United State therapeutic therapeutic antibodies United States vaccine breakthrough infections Viral yielding [DOI] 10.1038/s41586-022-05053-w PMC 바로가기 [Article Type] Article