Comprehensive evaluation of the efficacy and safety of LPV/r drugs in the treatment of SARS and MERS to provide potential treatment options for COVID-19
COVID-19에 대한 잠재적인 치료 옵션을 제공하기 위해 SARS 및 MERS 치료에서 LPV/r 약물의 효능 및 안전성에 대한 종합 평가
Meta-Analysis
[키워드] acute respiratory distress
acute respiratory distress syndrome
acute respiratory syndrome
addition
adverse event
adverse events
age and sex
analyzed
Antiviral treatment
applied
ARDS
assessment tool
benefit
bias risk
case-control studies
CBM
Chest CT
China
CNKI
Cochrane Library
Cohort studies
Combination
comprehensive evaluation
conducted
control group
conversion rate
coronavirus disease
Coronavirus disease 2019
Coronavirus infections
COVID-19
COVID-19 treatment
database
drug
effective
Effectiveness
Efficacy
Efficacy and safety
eligible
evaluate
exhibited
Factor
incidence
Infrastructure
literature
Lopinavir
Lopinavir/ritonavir
lower mortality
LPV/r
MERS
Meta-analysis
Middle East
Middle East respiratory syndrome
molecular
Newcastle-Ottawa Scale
NOS
nucleic acid
outbreak
outcome
patients
patients with COVID-19
patients with SARS
performed
potential treatment option
prognostic
Randomized controlled studies
RCT
reduced
Registration
respiratory
respiratory distress
retrieved
Risk assessment
Ritonavir
SARS
Severe acute respiratory syndrome
significantly
similarities
similarity
statistically significant
Structure
syndrome
systematic review
the Newcastle-Ottawa Scale
these viruses
Treatment
treatment of COVID-19
Trial
two group
two groups
virus clearance
viruses
was used
were used
[DOI] 10.18632/aging.202860 PMC 바로가기 [Article Type] Meta-Analysis
[DOI] 10.18632/aging.202860 PMC 바로가기 [Article Type] Meta-Analysis