clinical sensitivity – Page 4 – Communicable Diseases Research

Clinical validation of automated and rapid mariPOC SARS-CoV-2 antigen test

자동 및 빠른 Maripoc SARS-COV-2 항원 검사의 임상 검증

Article

Published on 2021-10-132022-09-01
Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료기술, 치료법,

Comparison of four commercial, automated antigen tests to detect SARS-CoV-2 variants of concern

우려되는 SARS-CoV-2 변이체를 탐지하기 위한 4가지 상용 자동화 항원 검사 비교

Comparative Study

Published on 2021-08-202022-09-10
Journal: Medical Microbiology and Immunology [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Alpha Amino acid Analysis analytical sensitivity Antigen Asymptomatic automated Automated SARS-CoV-2 antigen test B.1.1.7 B.1.351 Beta biosafety level Biosafety Level 3 biosafety level 3 laboratory Characteristics clinical isolates clinical sensitivity comparable complement Containment coronavirus Cutoff detect Detection limit determine diagnostic test diagnostic tests DiaSorin Efficacy Elecsy Elecsys ELISA Euroimmun evaluated FIVE Fujirebio Germany hospitalized patients implementation independent isolate Laboratory level 3 LIAISON Mutation nucleic acid nucleocapsid nucleocapsid protein pandemic PCR-negative PCR-positive performed platform POCT point-of-care Quantitative ranged Rapid respiratory Respiratory samples Roche Roche Diagnostics SARS-CoV-2 SARS-CoV-2 variant sensitivity Sensitivity and specificity Specificities specificity study cohort Swab symptomatic patient Test variant VoC VOCs widespread
[DOI] 10.1007/s00430-021-00719-0 PMC 바로가기 [Article Type] Comparative Study

Anti-SARS-CoV-2 Antibody Levels Measured by the AdviseDx SARS-CoV-2 Assay Are Concordant with Previously Available Serologic Assays but Are Not Fully Predictive of Sterilizing Immunity

AdviseDx SARS-CoV-2 분석으로 측정된 항-SARS-CoV-2 항체 수준은 이전에 사용 가능한 혈청학적 분석과 일치하지만 살균 면역을 완전히 예측하지는 못합니다

Article

Published on 2021-08-182022-09-11
Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법,

[키워드] 95% confidence interval Abbott Abbott Architect anti-SARS-CoV-2 anti-SARS-CoV-2 antibody Anti-spike antibody assay Antigen antigen binding Architect binding Breakthrough infection can not Characteristics clinical sensitivity concordant coronavirus correlates of protection COVID-19 demonstrated described Elecsy ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Euroimmun examined Factor fishing vessel FIVE Genscript Health care Health care worker healthy humoral Humoral response Immunoglobulin in vitro increasingly individual International international standard international units investigated Level median Neutralizing activity no significant difference outbreak Patient PCR peaked performed positive predicted Protective Protein Quantitative required Roche SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 vaccination seroconverting serologic Serological testing serology seropositive spike IgG Spike protein symptom onset vaccinated individuals vaccination Vaccine vaccine dose variants variants of concern vessel virus neutralization assay WHO widespread wild-type SARS-CoV-2
[DOI] 10.1128/JCM.00989-21 PMC 바로가기 [Article Type] Article

Saliva is Comparable to Nasopharyngeal Swabs for Molecular Detection of SARS-CoV-2

타액은 SARS-CoV-2의 분자 검출을 위한 비인두 면봉과 비슷합니다.

Research Article

Published on 2021-08-182022-09-10
Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료기술,

[키워드] a minor Abbott acquisition acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alternative average clinical sensitivity Concordance coronavirus COVID-19 COVID-19 testing decrease detection drink Follow-up food fraction guanidinium individual infectious risk initial leak less limit of detection limits Limits of detection majority medium minor molecular nasopharyngeal Nasopharyngeal swab NP swab NP swabs Outpatient outpatients Patient platform presenting respiratory restriction reverse transcriptase reverse transcriptase PCR RT-PCR Saliva saliva specimen saliva specimens SARS-CoV-2 severe acute respiratory syndrome Coronavirus smoking specimen specimen collection Swab tested Transport transport medium treated Viral Viral load viral loads Viral RNA virus
[DOI] 10.1128/Spectrum.00162-21 PMC 바로가기 [Article Type] Research Article

Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2

LumiraDx™의 정확성, 독점성, 검출 한계 및 사용 편의성 평가: SARS-CoV-2용 항원 검출 현장 진료 장치

Multicenter Study

Published on 2021-08-122022-09-10
Journal: Infection [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

[키워드] 95% CI Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Ag-RDT Ag-RDTs analytical sensitivity Antigen-detecting diagnostics calculate Chain Reaction clinical sensitivity clinical specificity collected conducted coronavirus COVID-19 cross-reactivity diagnostic Diagnostic accuracy enrolled evaluated immunofluorescence individual investigated nasal nasopharyngeal pandemic participant pathogen Pathogens point-of-care polymerase chain polymerase chain reaction positive Rapid RDTs registration date registration number reporting symptom respiratory Result resulting reverse transcriptase Reverse transcriptase polymerase chain reaction RNA RNA copies RT-PCR SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV2 Self-swab sensitivity Sensitivity and specificity severe acute respiratory syndrome Coronavirus supplementary material Swab Symptom symptomatic and asymptomatic Testing transcriptase Viral Viral load was increased
[DOI] 10.1007/s15010-021-01681-y PMC 바로가기 [Article Type] Multicenter Study

Saliva Testing Is Accurate for Early-Stage and Presymptomatic COVID-19

타액 검사는 초기 단계 및 전증상 COVID-19에 대해 정확합니다

Research Article

Published on 2021-07-142022-09-10
Journal: Microbiology Spectrum [Category] SARS, 진단, 치료기술,

[키워드] Analysis anatomical approach association best clinical sensitivity Clinical sign Clinical signs Cohort collected Concordance COVID-19 COVID-19 testing Decision making disease Disease prevalence disease stage effort evaluate gold gold standard Health care health care workers highlight Hospitalized in viral Infection knowledge lab Laboratory Laboratory test less medical record meta-analyses MONITOR Nasal sample nasal samples nasopharyngeal nasopharyngeal sample Nasopharyngeal samples offer participant Participants Personal protective equipment Population screening presymptomatic public health retained Saliva sample collection SARS-CoV-2 sensitivity Signs and symptoms Spread symptom onset symptomatic and asymptomatic Symptoms tested Testing the disease the timing utility Variability Viral Viral load virus was related
[DOI] 10.1128/Spectrum.00086-21 PMC 바로가기 [Article Type] Research Article

Diagnostic accuracy of Panbio rapid antigen tests on oropharyngeal swabs for detection of SARS-CoV-2

SARS-COV-2의 검출을위한 인두 면봉에 대한 Panbio 신속 항원 검사의 진단 정확도

Clinical Trial

Published on 2021-06-242022-08-13
Journal: PLoS ONE [Category] MERS, SARS, 임상, 진단, 치료기술,

[키워드] (Abbott Abbott Ag-RDT Ag-RDTs clinical sensitivity clinical specificity conducted COVID-19 COVID-19 pandemic criteria cut-off Cycle threshold value Cycle threshold values diagnostic Diagnostic accuracy diagnostic tests enrolled False positive in some incidence individuals Infectious virus nasopharyngeal nasopharyngeal swabs NPs offer Oropharyngeal oropharyngeal swab oropharyngeal swabs Outpatient PanBio pandemic patients positive Prospective Study qPCR quantitative PCR Rapid rapid antigen test Rapid diagnostic test Rapid test RDT RDTs required Result RT-qPCR RT-qPCR test SARS-CoV-2 SARS-CoV-2 genome sensitivity specificity specimen Swab Switzerland symptomatic individuals Test the WHO was obtained
[DOI] 10.1371/journal.pone.0253321 PMC 바로가기 [Article Type] Clinical Trial

Clinical Evaluation of the Abbott Alinity SARS-CoV-2 Spike-Specific Quantitative IgG and IgM Assays among Infected, Recovered, and Vaccinated Groups

Abbott Alinity SARS-CoV-2 스파이크 특이적 정량적 IgG 및 IgM 분석의 감염, 회복 및 백신 접종 그룹의 임상 평가

Article

Published on 2021-06-182022-09-11
Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 진단, 치료법,

[키워드] Abbott acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody Response Antibody responses Antibody test booster clinical clinical sensitivity Cohort collected Combination Containment coronavirus coronavirus disease Coronavirus infections COVID-19 COVID-19 vaccines cross-reactivity dampened response dose group Health IgG IgG and IgM IgM immune responses Immunity immunoassays individual individuals Infection Laboratory nucleocapsid pandemic participant Quantitative recovered respiratory response SARS-CoV-2 sensitivity serologic assay Serological assay serological response serology assay serology assays severe acute respiratory syndrome Coronavirus significant increase spike Spike protein unique utility vaccination Vaccine while
[DOI] 10.1128/JCM.00388-21 PMC 바로가기 [Article Type] Article

Comparison between RT-qPCR for SARS-CoV-2 and expanded triage in sputum of symptomatic and asymptomatic COVID-19 subjects in Ecuador

SARS-COV-2에 대한 RT-QPCR과 에콰도르의 증상 및 무증상 코비드 19 피험자의 가래에서 확장 된 심사의 비교

Comparative Study

Published on 2021-06-122022-09-01
Journal: BMC Infectious Diseases [Category] MERS, SARS, 진단, 치료기술,

[키워드] SARS-CoV-2;sensitivity 95% confidence interval Accuracy addition association Asymptomatic asymptomatic subject asymptomatic subjects calculated Chain Reaction clinical sensitivity Concordance confidence interval COVID-19 COVID-19 case Critical detect diagnostic Diagnostic accuracy Ecuador Efficacy hospital identify Kappa coefficient Laboratory Laboratory test lack Molecular diagnosis mortality rate polymerase chain reaction positive result Predictive predictive values qPCR test Quantitative reached Result Retrospective study reverse transcriptase RT-qPCR RT-qPCR test SARS-CoV-2 SARS-CoV-2 virus Sensitivity and specificity specificity sputum sputum samples subject subjects submitted Symptom symptomatic symptomatic and asymptomatic virus
[DOI] 10.1186/s12879-021-06272-8 PMC 바로가기 [Article Type] Comparative Study

Self-Sampling for SARS-CoV-2 Diagnostic Testing by Using Nasal and Saliva Specimens: Protocol for Usability and Clinical Evaluation

Protocol

Published on 2021-05-282022-10-29
Journal: JMIR Research Protocols [Category] COVID-19,

[키워드] approved benefit Care clinical clinical sensitivity clinical trial collected conducted COVID-19 COVID-19 pandemic Critical diagnostic diagnostics enrolled ethics committee evaluate feasibility General population Health Human Identifier implementation individual individuals Infection initial invasive nasal nasal swab Nasopharyngeal swab Novel coronavirus objective offer pandemic participant Patient positive potential risk Preliminary data processed protocol provided recruit recruited recruitment reduce reference method report Research Result Saliva SARS-CoV-2 SARS-CoV-2 testing SARS-CoV-2SS screened self-identification Self-sampling sensitivity shown South Africa specificity Spread standard reference Symptom tested Testing university Usability usabillity virus
[DOI] 10.2196/24811 PMC 바로가기 [Article Type] Protocol