Predictive risk factors for hospitalization and response to colchicine in patients with COVID-19Research article Published on 2022-03-012022-10-05 Journal: International Journal of Infectious Diseases [Category] SARS, 임상, 치료제, [키워드] age Anticoagulants benefit body-mass clinical trial Colchicine colchicine therapy colchicine treatment COVID-19 COVID-19 patient death diabete drugs Gender high-risk patient Hospitalization identify objective oral steroid Patient patients with COVID-19 predicted Predictive Prevent Probability randomization Respiratory disease response to colchicine Result retained risk factor Risk factors Sex study population subject the placebo group threshold threshold value treat variable was used [DOI] 10.1016/j.ijid.2022.01.020 [Article Type] Research article
Brazilian guidelines for the treatment of outpatients with suspected or confirmed COVID-19. A joint guideline of the Brazilian Association of Emergency Medicine (ABRAMEDE), Brazilian Medical Association (AMB), Brazilian Society of Angiology and Vascular Surgery (SBACV), Brazilian Society of Geriatrics and Gerontology (SBGG), Brazilian Society of Infectious Diseases (SBI), Brazilian Society of Family and Community Medicine (SBFMC), and Brazilian Thoracic Society (SBPT)Research article Published on 2022-03-012022-10-05 Journal: The Brazilian journal of infectious diseases : an [Category] 치료법, [키워드] AmB Angiology Anticoagulants benefit Brazil Colchicine convalescent plasma Corticosteroids COVID-19 COVID-19 drug treatment demonstrated Effectiveness Emergency evaluated Evidence family Gerontology GRADE guideline hydroxychloroquine/chloroquine implementation Infectious disease International Ivermectin joint limitation Medicine methodologist Ministry of Health monoclonal antibody Outpatient outpatients promote recommendation resource responsible Result SARS-CoV-2 Society Support surgery therapy Treatment was used with COVID-19 [DOI] 10.1016/j.bjid.2022.102347 [Article Type] Research article
Clinical course of COVID-19 infection in paediatric familial Mediterranean fever patientsArticle Published on 2022-02-282023-07-07 Journal: Modern rheumatology [Category] COVID19(2023년), [키워드] children Colchicine coronavirus COVID‐19 infection Familial Mediterranean fever [DOI] 10.1093/mr/roab056
COVID-19 in patients with Behçet’s disease: Outcomes and rate of Behçet’s exacerbations in a retrospective cohortArticle Published on 2022-02-282022-11-16 Journal: Modern rheumatology [Category] COVID19(2023년), SARS, 치료기술, [키워드] activity Behcet’s disease calculated clinical feature Cohort Colchicine collected comorbid disease coronavirus coronavirus disease COVID-19 COVID-19 in patient current demographics Diagnosis died disease form Frequency Hospitalized hospitalized patients ICU ICU admission investigated medical record Mortality Older age outcome Patient patient cohort patients PCR PCR-positive patient polymerized positive positive PCR positive PCR test reached retrospective cohort suffered Symptom Symptoms with COVID-19 [DOI] 10.1093/mr/roab016 PMC 바로가기
Mechanism of Caspase-1 Inhibition by Four Anti-inflammatory Drugs Used in COVID-19 TreatmentCOVID-19 치료에 사용되는 4가지 항염증제에 의한 Caspase-1 억제 메커니즘Article Published on 2022-02-062022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, 치료제, [키워드] “cytokine storm” active site activity alleviate Amino acid analyzed anti-inflammatory drug Anti-inflammatory drugs antioxidant carbonyl caspase caspase-1 cause causes Colchicine Compound Computational methods Corticosteroid covalent bond COVID-19 COVID-19 infection COVID-19 therapy COVID-19 treatment cytokine cytokine release Cytokine storm Cytokines death Dexamethasone drug drugs effective excessive cytokine production help indicated Inflammatory Inflammatory response inhibition inhibitor mechanism Methylprednisolone molecular protease protons raloxifene reported residue scavenging Superoxide therapy these compounds transfer Treatment Trigger triggers [DOI] 10.3390/ijms23031849 PMC 바로가기 [Article Type] Article
Repurposing the drug, ivermectin, in COVID-19: toxicological points of viewCovid-19에서 약물, Ivermectin의 용도 : 독성 관점Review Published on 2022-02-052022-08-31 Journal: European Journal of Medical Research [Category] 신약개발, 임상, 치료제, [키워드] affected appear Behavior changes in clinician Colchicine Coronavirus disease 2019 COVID-19 COVID-19 pandemic dose drug effective Effectiveness evaluated except for FDA food Food and Drug Administration in vitro inhibitory activity interferon Ivermectin medication observational studies pandemic patients with COVID-19 potential therapies question repurposing Safe SARS-CoV-2 SARS-CoV-2 replication shown Side effects social distancing steroid Steroids suggested therapeutic effect Tocilizumab Treatment treatment of COVID-19 [DOI] 10.1186/s40001-022-00645-8 PMC 바로가기 [Article Type] Review
Colchicine – new horizons for an ancient drug. Review based on the highest hierarchy of evidenceReview Published on 2022-02-012023-07-06 Journal: European journal of internal medicine [Category] COVID19(2023년), [키워드] Behcet's syndrome Colchicine Coronary artery disease/Ischemic stroke COVID-19 Pericarditis and Postcardiac Injury Syndrome Randomized-controlled-trials secondary prevention [DOI] 10.1016/j.ejim.2021.10.002 [Article Type] Review
Effect of colchicine on mortality in patients with COVID-19 – A systematic review and meta-analysis콜히친이 COVID-19 환자의 사망률에 미치는 영향 - 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-02-012022-09-11 Journal: Diabetes & metabolic syndrome [Category] COVID19(2023년), SARS, 신약개발, 임상, [키워드] age Analysis association Colchicine colchicine group control group controlled trials coronavirus Course COVID-19 decreased mortality diabete diabetes Effect evaluate Evidence hypertension include intervention group Meta-analysis meta-regression Mortality mortality rate not affected observational studies observational study outcome Patient patients with COVID-19 performed Placebo Randomized controlled trial randomized trial randomized trials RCT RCTs reduced reduction in mortality reported risk risk ratio SARS-CoV-2 sensitivity analysis Sex significant effect Standard of care subgroup analysis systematic review Treatment [DOI] 10.1016/j.dsx.2022.102395 PMC 바로가기 [Article Type] Meta-Analysis
Efficacy and safety of colchicine treatment in patients with COVID-19: A prospective, multicenter, randomized clinical trialRandomized Controlled Trial Published on 2022-02-012023-07-08 Journal: Phytotherapy research : PTR [Category] COVID19(2023년), [키워드] clinical trial Colchicine COVID-19 SARS-CoV2 [DOI] 10.1002/ptr.7319 [Article Type] Randomized Controlled Trial
Divergent impacts of tocilizumab and colchicine in COVID-19-associated coagulopathy: the role of alpha-defensinsCOVID-19 관련 응고병증에서 토실리주맙과 콜히친의 다양한 영향: 알파 방어소의 역할Clinical Trial Published on 2022-02-012022-09-12 Journal: British Journal of Haematology [Category] MERS, 임상, 진단, [키워드] Administered affected anti-IL-6 receptor anti-inflammatory agent anticipated clinical trial Coagulation Colchicine coronavirus disease COVID-19 Cytokine storm D-dimer level D-dimer levels develop Effect event human neutrophil IL-6 Impact include increase in Inflammation inhibit interleukin-6 mitigate monoclonal antibody Neutrophils Patient patients with COVID-19 peptide performed polymerase chain positive pro-thrombotic promote raising recorded reduced reflected significantly increased stimulated stimulatory TCZ thrombosis Tocilizumab treated treatment with colchicine Trial Trigger [DOI] 10.1111/bjh.17885 PMC 바로가기 [Article Type] Clinical Trial