Serum hemato-immunological biomarkers associated with increased COVID-19 mortality in the Latino population라틴계 인구에서 COVID-19 사망률 증가와 관련된 혈청 혈액 면역학적 바이오마커Observational Study Published on 2022-07-012022-09-11 Journal: Biomarkers in Medicine [Category] MERS, 바이오마커, 임상, 진단, [키워드] Biomarker Comorbidity COVID-19 COVID-19 hospitalization COVID-19 mortality COVID-19 patient death followed by Hospitalization increased mortality independent Inflammatory inflammatory biomarkers Latino leukocyte lymphocyte median age men moderate disease Mortality neutrophil Neutrophil-to-lymphocyte ratio obesity overweight patients Platelet predictor Prognostic factor Prognostic factors pulmonary damage raised Retrospective study Serum inflammatory biomarkers severe disease [DOI] 10.2217/bmm-2022-0056 PMC 바로가기 [Article Type] Observational Study
Tracking of SARS-CoV-2 Alpha variant (B.1.1.7) in Palestine팔레스타인에서 SARS-CoV-2 알파 변종(B.1.1.7) 추적Article Published on 2022-07-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant Analysis analyzed B.1.1.7 bootstrap clade Cluster collected COVID-19 COVID-19 mortality COVID-19 pandemic Diagnosis disease severity effective F-statistic gene flow Genetic variation genetics genome sequence homogenous Hypothesis impacted introduced Nablus new SARS-CoV-2 Palestine peaked Phylogenetic tree Population genetics remains uncertain replaced SARS-CoV-2 SARS-CoV-2 surveillance SARS-CoV-2 variants sequenced statistically statistically significant supported Tajima therapy Transmission Vaccine-induced immunity variant virulence WGS whole genome sequence wild type [DOI] 10.1016/j.meegid.2022.105279 PMC 바로가기 [Article Type] Article
The influence of structural racism, pandemic stress, and SARS-CoV-2 infection during pregnancy with adverse birth outcomes구조적 인종 차별주의, 대유행 스트레스 및 임신 중 SARS-CoV-2 감염의 영향으로 부정적인 출생 결과Article Published on 2022-07-012022-09-12 Journal: American journal of obstetrics & gynecology MFM [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% confidence interval adjusted adjusted analyses adjusted relative risk analyzed Asian association black blood sample body mass index Clustering Community COVID-19 COVID-19 mortality COVID-19 pandemic database dependent variable enzyme-linked immunosorbent evaluated Factor highest increase increased risk independent Infants Infection joint lowest maternal age measure Model neighborhood New York City Newborn no interaction obese outcome outcomes pandemic Patient Pregnancy pregnant Preterm birth prospective cohort quartile racism reduce risk robust SARS-CoV-2 SARS-COV-2 infection seropositive small-for-gestational-age standard error Stress synergistic unemployment was performed white zone [DOI] 10.1016/j.ajogmf.2022.100649 PMC 바로가기 [Article Type] Article
Human ACE2 Polymorphisms from Different Human Populations Modulate SARS-CoV-2 Infection다양한 인간 집단의 인간 ACE2 다형성이 SARS-CoV-2 감염을 조절합니다Article Published on 2022-06-302022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 ACE2 variant ACE2 variants acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect Asian caused cell entry receptor cells contrary coronavirus COVID-19 COVID-19 mortality COVID-19 pandemic COVID-19 symptom COVID-19 symptoms death determinant E35K ENCODE environmental factor Ethnic groups expression Genetic genetic determinant hACE2 high variability Host Human human ACE2 Human genome human population Infection modulate pandemic polymorphism Polymorphisms Population populations PROTECT Protective protective effect reduced risk SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe COVID-19 severity of COVID-19 surface expression susceptibility Symptoms two allele Two alleles variant virus infection wild-type [DOI] 10.3390/v14071451 PMC 바로가기 [Article Type] Article
Overhydration Assessed Using Bioelectrical Impedance Vector Analysis Adversely Affects 90-Day Clinical Outcome among SARS-CoV2 Patients: A New Approach생체 전기 임피던스 벡터 분석을 사용하여 평가된 과수화는 SARS-CoV2 환자의 90일 임상 결과에 부정적인 영향을 미칩니다: 새로운 접근 방식Article Published on 2022-06-302022-09-11 Journal: Nutrients [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] 95%CI Admission Affect assessment assist Biomarker body water Care clinical clinical assessment COVID-19 COVID-19 mortality COVID-19 patient COVID-19 patients creatinine cut-off value determine Extracellular extracellular water greater highest Hospital admission Hydration hydration fat-free mass hydration status ICU identify impedance increased mortality indicated Inflammation intensive care unit Laboratory marker measure Medical care medical condition Mortality Multivariate analysis New offer Overhydration pandemic parameters Patient poor prognosis prealbumin predict Predictive predictor prognostic Prognostic factors proportion Research risk risk factor SARS-CoV2 sensitivity significantly significantly higher specificity survival survival and mortality analysis total body total body water total body water. vector water [DOI] 10.3390/nu14132726 PMC 바로가기 [Article Type] Article
Glycaemic variability is associated with all-cause mortality in COVID-19 patients with ARDS, a retrospective subcohort study Research Published on 2022-06-142022-10-05 Journal: Scientific Reports [Category] 바이오마커, 임상, 치료법, [키워드] Aachen acute respiratory distress adjusted all-cause mortality ARDS caused clinically cohort study confounders Continuous coronavirus disease COVID-19 COVID-19 mortality COVID-19 patient death diabete diabetes elevated Factor Germany Glucose high mortality ICU ICU admission increase in intensive care Kaplan–Meier estimator likelihood mechanical ventilation median Metrics moderate Mortality mortality risk P/F ratio Patient patients with COVID-19 plasma procalcitonin retrospective severe ARDS significant increase statistically significant difference survival syndrome university Variability with COVID-19 [DOI] 10.1038/s41598-022-13816-8 [Article Type] Research
International comparisons of laboratory values from the 4CE collaborative to predict COVID-19 mortality Research Published on 2022-06-132022-10-05 Journal: NPJ Digital Medicine [Category] 유전자 메커니즘, [키워드] Admission age albumin Algorithm approach AST baseline Cohort Combination Comorbidity comparison country covariate COVID-19 hospitalization COVID-19 mortality Cox model Cox regression model CRP demographics died Europe evaluated feature Generalizability Healthcare system Healthcare systems highlighting hospitalized patient Laboratory male Model Mortality nine patients hospitalized predict predicted Predictive White blood cell with COVID-19 [DOI] 10.1038/s41746-022-00601-0 [Article Type] Research
SCD14-ST and New Generation Inflammatory Biomarkers in the Prediction of COVID-19 OutcomeCovid-19 결과의 예측에서 SCD14-ST 및 신세대 염증 바이오 마커Article Published on 2022-06-132022-08-31 Journal: Biomolecules [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] addition Biomarker Biomarkers canonical clinical feature Clinical features COVID-19 COVID-19 mortality COVID-19 positive patients CRP cytokine Cytokine storm Cytokines cytokines IL-6 died discharged disease Generation ICU ICU Patients IL-10 IL-6 immune immune biomarkers Infection inflammatory biomarkers Inflammatory marker inflammatory markers inflammatory parameters Laboratory Longitudinal evaluation longitudinal study New new infection outcome Patient plasma-EDTA predict prediction prediction of disease. prognostic SARS-CoV-2 SCD14-ST severity significantly higher suPAR the disease to define were measured [DOI] 10.3390/biom12060826 PMC 바로가기 [Article Type] Article
Estrogen hormone is an essential sex factor inhibiting inflammation and immune response in COVID-19에스트로겐 호르몬은 COVID-19에서 염증과 면역 반응을 억제하는 필수 성 인자입니다Article Published on 2022-06-082022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 신약개발, 유전자 메커니즘, 임상, 진단, 치료법, 치료제, [키워드] age approved caused COVID-19 COVID-19 mortality COVID-19 patient COVID-19 patients COVID-19 treatment death drug effective ESR1 ESR2 estradiol estriol Estrogen Estrogens estrone evaluated Factor Fatality rate female Genetic genetic factors Host host cells immune response increase indicated infected with SARS-CoV-2 Inflammation inhibit SARS-CoV-2 inhibiting lack male mechanism medication medications men Mortality mortality rate network analysis proportion PROTECT receptors reduce SARS-COV-2 infection Sex Signaling signaling pathway signaling pathways significantly synergistic target targets Treatment unique Vaccine with COVID-19 women [DOI] 10.1038/s41598-022-13585-4 PMC 바로가기 [Article Type] Article
Clinical Characteristics and Prognosis of COVID-19 patients in Syria: A cross-sectional multicenter studyResearch article Published on 2022-06-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 바이오마커, 유전자 메커니즘, [키워드] advanced age age Biomarker Care clinical Clinical characteristics Clinical data Clinical outcome collected Comorbidities Comorbidity COVID-19 COVID-19 mortality COVID-19 patient cross-sectional demographic Diabetes Mellitus died discharged elevated Fever global pandemic Healthcare system high-risk patient highest hospital hypertension International lactate dehydrogenase lung lymphocyte counts majority male material Mortality multicenter multiple comorbidity multivariable analysis National normalized outcome Patient patients polymerase chain positive predictive power Prevalence Prognosis prognostic indicator Prospective Study reduce reported Respiratory failure respiratory rate Result risk risk factor Shortness of breath significantly Stage strained Symptom Syria the disease university hospital White blood cell [DOI] 10.1016/j.amsu.2022.103816 [Article Type] Research article