Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquitoArticle Published on 2021-06-012024-08-28 Journal: Microbial Cell Factories [Category] 말라리아, [키워드] Anopheles CRISPR-Cas gene drive Off-Target vector control
Intrinsic signal amplification by type III CRISPR-Cas systems provides a sequence-specific SARS-CoV-2 diagnostic유형 III CRISPR-Cas 시스템에 의한 고유 신호 증폭은 서열 특이적 SARS-CoV-2 진단을 제공합니다Report Published on 2021-05-272022-09-10 Journal: Cell Reports Medicine [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] Abstract activate Activation amplification amplified product ATP clinically complementary complex conserved conserved regions COVID-19 CRISPR CRISPR Dx CRISPR-Ca CRISPR-Cas decrease detect detectable diagnostic domain followed by generate guide RNA IMPROVE less limit of detection Multiplexing oligonucleotides Patient point-of-care diagnostics polymerase proton protons provide Recognition Region RNA RT-LAMP SARS-CoV-2 SARS-CoV-2 genomes SARS-CoV-2 RNA sensitivity Trigger triggers type III viral diagnostics viruses [DOI] 10.1016/j.xcrm.2021.100319 PMC 바로가기 [Article Type] Report
COVID-19 one year later: a retrospect of CRISPR-Cas system in combating COVID-191년 후의 COVID-19: COVID-19 퇴치를 위한 CRISPR-Cas 시스템의 회고Review Published on 2021-05-132022-09-10 Journal: International Journal of Biological Sciences [Category] SARS, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adaptive immune system application caused combating coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis COVID-19 pandemic CRISPR CRISPR-Ca CRISPR-Cas Diagnosis Disease diagnosis Drug discovery effective therapy Emergency evaluated focus gene editing hidden human gene imperative Infectious disease limitation mechanism research Palindromic Perspective Prevent Protein Rapid Repeat respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread Therapeutics therapy transmission of SARS-CoV-2 Treatment Viral Viral RNA [DOI] 10.7150/ijbs.60655 PMC 바로가기 [Article Type] Review
Biosensing Detection of the SARS-CoV-2 D614G MutationArticle Published on 2021-04-012023-07-13 Journal: Trends in genetics : TIG [Category] SARS, [키워드] CRISPR-Cas hybridization Loop-mediated isothermal amplification (LAMP) Nanopore restriction endonucleases spike [DOI] 10.1016/j.tig.2020.12.004 PMC 바로가기
Recent trends in analytical and digital techniques for the detection of the SARS-Cov-2SARS-Cov-2 탐지를 위한 분석 및 디지털 기술의 최근 동향Review Published on 2021-03-012022-09-11 Journal: Biophysical chemistry [Category] SARS, 치료기술, [키워드] antigens biosensors chain Chain Reaction Clinical diagnosis colorimetric detection system component confirmation COVID-19 CRISPR CRISPR-Ca CRISPR-Cas detect detection technique develop disease exhibiting fluorescent followed by gold gold standard gravity immune response immunosensor management Microarray next generation sequencing Next-generation sequencing Nucleic-acid amplification outbreak PCR platform point of care polymerase chain reaction reaction real time Polymerase Chain Reaction recent risk RT-PCR RT-PCR detection SARS-CoV-2 Sensitivity and specificity serological test susceptible the disease the SARS-CoV-2 Viral Viral RNA [DOI] 10.1016/j.bpc.2020.106538 PMC 바로가기 [Article Type] Review
Enlarging the Toolbox Against Antimicrobial Resistance: Aptamers and CRISPR-CasMicrobiology Published on 2021-02-192022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] Against alternative treatments antimicrobial antimicrobial resistance approaches aptamer Bacterial infections Characteristics CRISPR-Ca CRISPR-Cas diagnostic diagnostics highlight molecular molecular diagnostic practicality researcher robust Support targets Treatment variety [DOI] 10.3389/fmicb.2021.606360 PMC 바로가기 [Article Type] Microbiology
Detection of severe acute respiratory syndrome coronavirus 2 and influenza viruses based on CRISPR-Cas12aArticle Published on 2020-11-052023-06-14 Journal: Experimental Biology and Medicine [Category] MERS, SARS, [키워드] CRISPR-Cas detection influenza A influenza B RT-RPA SARS-CoV-2 [DOI] 10.1177/1535370220963793 PMC 바로가기
CRISPR-Based Diagnosis of Infectious and Noninfectious DiseasesReview Published on 2020-09-142022-10-27 Journal: Biological Procedures Online [Category] COVID-19, [키워드] adaptive assays Bacterial Cancer Cas9 cleavage cleaving COVID-19 CRISPR CRISPR-Ca CRISPR-Cas detect DETECTR diagnosed Diagnosis diagnosis of COVID-19 diagnostic test Diseases DNA enzyme Enzymes foreign DNA Genetic Genome Human genome Immunity initial interest Laboratory lateral flow mechanism medical diagnostics microorganism non-infectious non-infectious disease Patient performed reagent reduce resolved RNA SARS-CoV-2 virus Scientific community SHERLOCK shown Side effect significantly Single guide RNA (sgRNA) subtype variety while [DOI] 10.1186/s12575-020-00135-3 PMC 바로가기 [Article Type] Review
Insertion sequences in the CRISPR-Cas system regulate horizontal antimicrobial resistance gene transfer in Shigella strainsarticle Published on 2019-02-282024-09-01 Journal: International Journal of Antimicrobial Agents [Category] 세균성이질, [키워드] antimicrobial resistance CRISPR-Cas Horizontal gene transfer insertion sequence IS600 Shigella [Article Type] article
Comparative genomics of Salmonella enterica serovar Montevideo reveals lineage-specific gene differences that may influence ecological niche association살모넬라 엔테리카 세로바르 몬테비데오의 비교 유전체학은 생태적 니치 연관성에 영향을 미칠 수 있는 계통 특이적 유전자 차이를 드러냅니다.Article Published on 2018-08-272024-07-29 Journal: Microbial Genomics [Category] 살모넬라증, [키워드] cattle Comparative genomics CRISPR-Cas Phylogenetic Salmonella enterica serovar Montevideo [DOI] 10.1099/mgen.0.000202 PMC 바로가기