Computational Analysis of Mutations in the Receptor-Binding Domain of SARS-CoV-2 Spike and Their Effects on Antibody Binding
Article
[키워드] ACE2
ACE2 binding
ACE2 receptor
administration
amino acid replacement
Analysis
analyzed
antibody
antigenic
antigenic escape
approaches
binding
binding affinity
binding free energy
bioinformatics
Cluster
complexes
computational analysis
computational mutagenesis
coronavirus disease
Coronaviruses
COVID-19
Deleterious
Effect
epitope
Epitopes
feature
hACE2
human ACE2 receptor
human cell
identify
impairment
indicate
Infection
Interaction
monoclonal
multiple mutation
multiple mutations
Mutation
Neutralizing
neutralizing antibody
Pandemics
performed
produced
Protein
RBD
RBD mutation
RBD variant
reduce
resolved
responsible
S-protein
SAR-CoV-2
SARS-CoV-2
sequence
spike
Strains
Structure
the RBD
the receptor-binding domain
the SARS-CoV-2
the vaccine
Trigger
Vaccines
variants of SARS-CoV-2
virus–host interactions
[DOI] 10.3390/v14020295 PMC 바로가기 [Article Type] Article
[DOI] 10.3390/v14020295 PMC 바로가기 [Article Type] Article