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[키워드] 30-Day mortality absence activities approved Arm blinded calculated Chest clinic clinical co-morbidities co-morbidity comparator coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 symptom Data collection death dissemination doctor ECMO Effectiveness element Endpoint enrolment Evidence evidence of excluded FIVE GRADE Grade 1 grade 3 Grade 5 group groups high resolution high resolution CT high-flow oxygen therapy Hospitalized HRCT Infection institutional review board Intention Invasive mechanical ventilation Ivermectin lung lobe mechanical ventilation morbidities nasal no evidence of noninvasive normal saline number objective outcome outcome assessor outcome assessors oxygen Oxygen therapy oxygen) Pakistan participant Patient patient recruitment patients with moderate PCR Physicians Placebo placebo group placebo-controlled positive pregnant women presence or absence primary care primary endpoints protocol radiological improvement randomisation randomised randomised controlled trial Randomized randomized clinical trial Randomly receive recorded Registered reported requiring supplemental oxygen Sample size SARS-CoV-2 SARS-CoV-2 clearance secondary endpoint seven-point scale severe respiratory syndrome severity Standard standard care status Study protocol Subcutaneous Ivermectin supplemental oxygen supplementary material symptomatic synergy Trial website Zinc
[DOI] 10.1186/s13063-021-05487-z PMC 바로가기 [Article Type] Letter