Student-led curricular approaches in medical education: the educational effects of a virtual fundamentals of COVID-19 courseResearch Published on 2022-03-082022-10-28 Journal: BMC Medical Education [Category] Coronavirus, MERS, SARS, [키워드] 95% CI approach asked Clinical practice Community Complete Composite Course COVID-19 COVID-19 pandemic creating curriculum domain domains Effect effective Effects enrolled Evidence examined finding healthcare implication increase in knowledge Likert scale medical students Medicine notable occurred pandemic provided question response Result School self-assessment statistically significant statistically significant difference student supplementary material Support undergraduate medical education university [DOI] 10.1186/s12909-021-03076-x PMC 바로가기 [Article Type] Research
Task-driven knowledge graph filtering improves prioritizing drugs for repurposingResearch Published on 2022-03-042022-10-27 Journal: BMC Bioinformatics [Category] Coronavirus, Fulltext, MERS, [키워드] Antiviral compound applied average can be used Compound connection disease Diseases domain domains drug Drug repurposing drugs Efficiency example Genes IMPROVE Increases information knowledge Knowledge graph embeddings Knowledge graphs Link prediction predict reduce Result resulting SARS CoV-2 supplementary material target while [DOI] 10.1186/s12859-022-04608-y PMC 바로가기 [Article Type] Research
Task-driven knowledge graph filtering improves prioritizing drugs for repurposing작업 중심의 지식 그래프 필터링은 용도의 약물 우선 순위를 향상시킵니다Research Published on 2022-03-042022-09-10 Journal: BMC Bioinformatics [Category] 신약개발, [키워드] abundance Antiviral compound Antiviral compounds applied average can be used Compound connection disease Diseases domain domains drug Drug repurposing drugs Efficiency example Genes graph IMPROVE incident Increases information knowledge Knowledge graph Knowledge graph embeddings Knowledge graphs lead Link prediction predict reduce Result resulting SARS CoV SARS CoV-2 supplementary material target use cases while [DOI] 10.1186/s12859-022-04608-y PMC 바로가기 [Article Type] Research
Development of Advanced Artificial Intelligence and IoT Automation in the Crisis of COVID-19 DetectionReview Article Published on 2022-03-022022-10-31 Journal: Journal of Healthcare Engineering [Category] COVID-19, MERS, [키워드] accelerated Accuracy activities Analysis artificial artificial intelligence Automation Characteristics cough coughing COVID-19 COVID-19 pandemic crisis detection development diagnosing Diagnosis domains effort Health Service healthcare instances intelligence Internet investigated memory organization Patient predict prenatal quarantine Research Respiratory samples risk the epidemic [DOI] 10.1155/2022/1987917 PMC 바로가기 [Article Type] Review Article
Bayesian-based optimized deep learning model to detect COVID-19 patients using chest X-ray image data흉부 X선 영상 데이터를 이용한 코로나19 환자 검출을 위한 베이지안 기반 최적화 딥러닝 모델Article Published on 2022-03-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 치료기술, [키워드] Accuracy Analysis artefact artificial artificial intelligence assist Bayesian Bayesian optimization changed chest X-ray Chest X-ray image Chest X-ray images CNN components Convolutional neural network coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critical dataset deep deep learning detect domain domains Features globe Image image classification intelligence learning optimization provided recent Recognition Research Research question researchers shown suggested variety [DOI] 10.1016/j.compbiomed.2022.105213 PMC 바로가기 [Article Type] Article
Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core협력 다가 수용체 결합은 SARS-CoV-2 융합 기계 코어의 노출을 촉진합니다Article Published on 2022-02-222022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 ACE2 binding ACE2 receptor ACE2 receptors acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 binding binding affinity Cell conformational Cooperative coronavirus dissociation domains event induce Interaction membrane fusion molecular molecular dynamics Molecular dynamics simulation Population promote Protein Proteins receptor Receptor binding recognize S1 and S2 S1 and S2 domains S1 domain S1/S2 cleavage SARS-CoV-2 severe acute respiratory syndrome Coronavirus spike spike glycoprotein Spike proteins spike trimer spike trimers the SARS-CoV-2 therapeutic tomography variant virus [DOI] 10.1038/s41467-022-28654-5 PMC 바로가기 [Article Type] Article
The relationship between frailty, nutritional status, co-morbidity, CT-body composition and systemic inflammation in patients with COVID-19Research Published on 2022-02-212022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] 30-Day mortality Admission age body composition CFS Clinical outcome co-morbidity collected COPD COVID-19 criteria domains elderly for inclusion frailty majority male marker Mortality NLR nutritional status obesity Patient patients with COVID-19 prognostic Prognostic factor regression analysis remained Result sarcopenic scale Screening significantly study inclusion systemic inflammation Universal variables were assessed with COVID-19 [DOI] 10.1186/s12967-022-03300-2 PMC 바로가기 [Article Type] Research
The emotional side of post-traumatic stress reaction during COVID-19 pandemic: an Italian surveyResearch Published on 2022-02-162022-10-28 Journal: BMC Public Health [Category] COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] age alcohol Analysis approach association Care condition COVID-19 COVID-19 pandemic cross-sectional decrease domain domains emotional females Gender implementation increase increase in independent variable Italian lifestyle mental health modifications Older outcome pandemic physical activity physiological Poisson regression post-traumatic Prevalence Psychological distress questionnaire recruited respondent Result Sleep disturbance Sociodemographic characteristics Stress subject supplementary material was used younger people [DOI] 10.1186/s12889-022-12749-1 PMC 바로가기 [Article Type] Research
Analysis of the Neutralizing Activity of Antibodies Targeting Open or Closed SARS-CoV-2 Spike Protein ConformationsArticle Published on 2022-02-142022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] ACE2 activity analyzed binding binding affinity binding affinity prediction circulating complex conformation conformations contribute COVID-19 domains elicit elicited enzyme Epitopes escape fractions fraction Fractions immune response immunodominant immunogens immunoinformatics in silico infected patients information inhibit mRNA-1273 NAb neutralizing antibody Patient plasma polyclonal polyclonal plasma pre-fusion predict predicted Prevent SARS-CoV-2 SARS-COV-2 infection spike Spike protein Spike protein variants Strains Structure suggested target targeting the spike protein to define trajectory trimer Vaccine Vaccines variant virus [DOI] 10.3390/ijms23042078 PMC 바로가기 [Article Type] Article
Spatial Dynamics and Multiscale Regression Modelling of Population Level Indicators for COVID-19 Spread in MalaysiaArticle Published on 2022-02-132022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Analysis autocorrelation average calculated caused Cluster coast computational method COVID-19 determinant determine domains Dynamics East evaluate incidence indicated Indicator Level Local Malaysia occur Population positive Region regions Regression regression modelling resource SAR Spatial analysis spatiotemporal Spread spread of COVID-19 targeted intervention Transmission [DOI] 10.3390/ijerph19042082 PMC 바로가기 [Article Type] Article