Impact of vaccination on hospitalization and mortality from COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experienceArticle Published on 2022-09-232022-11-15 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, 치료기술, 치료제, [키워드] Antiviral B.1.1.529 changed cohorts cohorts of patient COVID-19 COVID-19 in patient CVID dominant early stage elevated Fatality rate General population Hospitalization immunodeficiency immunodeficient patient Impact improvement inborn errors of immunity individual Intervention monoclonal antibody morbidity and mortality Mortality MOST naïve nasopharynx omicron outcome pandemic Patient patients PCR PID Primary Immunodeficiency reduced risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine secondary immunodeficiency serological response severe COVID-19 shown significantly significantly increased the SARS-CoV-2 Treatment treatment strategy United Kingdom vaccination vaccine dose variant Viral detection viral variant widespread [DOI] 10.3389/fimmu.2022.984376 PMC 바로가기
Issues regarding COVID-19 in kidney transplantation in the ERA of the Omicron variant: a commentary by the ERA Descartes Working GroupArticle Published on 2022-09-222022-11-15 Journal: Nephrology, dialysis, transplantation : official p [Category] SARS, 변종, 치료제, [키워드] acute respiratory syndrome ambulatory patients Antiviral Antiviral agents antiviral drug Breakthrough infection Clinical practice concerning coronavirus coronavirus disease COVID-19 criteria Deceased depleting Developing dominant donors drug-to-drug interactions education Efficacy European group immunization Immunosuppression implementation Infection issue kidney kidney donation kidney transplant recipient kidney transplant recipients Kidney transplantation management omicron Prophylactic question raised recommendation risk SARS-CoV-2 Science severe disease shielding T cell transplantation Treatment treatment strategy vaccination variant widespread with COVID-19 working [DOI] 10.1093/ndt/gfac203 PMC 바로가기
Outcome and effect of vaccination in SARS-CoV-2 Omicron infection in hemodialysis patients: a cohort studyArticle Published on 2022-09-222022-11-16 Journal: Nephrology, dialysis, transplantation : official p [Category] SARS, 변종, [키워드] adjusted Admissions age analyzed clinical epidemiology cohort study Comorbidity Course COVID-19 Cox proportional hazard dialysis died disease severity dissemination dominant dose doses driven by Efficacy first dose Hemodialysis high risk Hospitalized incidence Infection information less majority Mild observation period omicron Patient positive predictor variable provided reducing reduction in Regression model risk SARS-CoV-2 SARS-COV-2 infection second dose Severity of infection the epidemic vaccination Vaccine vaccine doses variant [DOI] 10.1093/ndt/gfac209 PMC 바로가기
SARS-CoV-2 antibody dynamics in blood donors and COVID-19 epidemiology in eight Brazilian state capitals: A serial cross-sectional studyArticle Published on 2022-09-222022-11-15 Journal: eLife [Category] SARS, 변종, 진단, [키워드] age antibody waning attack rate Blood blood donor Blood donors Brazil circulating complex country COVID-19 COVID-19 situation CrI cross-sectional disease dominant Donor eight Epidemic Epidemics Epidemiology fatality Fatality rate Fazer foundation Gamma Gate global health health system heterogeneity highlight hospitalisation IFR IgG antibody Infection Infection fatality rate JBS Medical Research Council morbidity Older outbreak ranged respiratory pathogen SARS-CoV-2 SARS-CoV-2 antibody second wave sensitivity Seroprevalence Serosurveillance significantly Society specificity Spread supported tested understanding utility variant viruses VoC Weekly Wellcome Trust were used women [DOI] 10.7554/eLife.78233 PMC 바로가기
Single-Cell Gene Expression Analysis Revealed Immune Cell Signatures of Delta COVID-19Article Published on 2022-09-212022-11-16 Journal: Cells [Category] SARS, 변종, 유전자 메커니즘, [키워드] accompanied accompany adaptive B.1.617 Blood caused Characteristics contribute coronavirus disease correlated COVID-19 COVID-19 pathogenesis Cytokine storm Delta delta variant diagnostic dominant Factor Gene Expression gene expression signature high mortality highlight immune immune component immune response immune system Immunity immunological individual Infection Lineage lymphoid molecular monocyte Monocytes mononuclear cell Multiple myeloid cells pathway performed proinflammatory required Revealed risk SARS-CoV-2 SARS-CoV-2 lineage severity signature significant changes in single-cell syndrome targeted therapy therapeutic Transcriptome understanding variant virus with COVID-19 [DOI] 10.3390/cells11192950 PMC 바로가기
Virological features and pathogenicity of SARS-CoV-2 Omicron BA.2Article Published on 2022-09-202022-10-06 Journal: Cell Reports Medicine [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome antibody BA.1 BA.2 Body weight loss circulating coronavirus COVID-19 Critical dependent on dominant feature in vitro in vivo models indicate investigated K18-hACE2 mice less lung Lungs nasal turbinate nasal turbinates omicron pathogenicity protease public health recent replicate Replication SARS-CoV-2 SARS-CoV-2 variant serine 2 survival TMPRSS2 transmembrane Virological virus entry [DOI] 10.1016/j.xcrm.2022.100743 PMC 바로가기 [Article Type] Article
Prevalence, incidence and longevity of antibodies against SARS-CoV-2 among primary healthcare providers in Belgium: a prospective cohort study with 12 months of follow-upArticle Published on 2022-09-192022-11-15 Journal: BMJ Open [Category] SARS, 변종, 진단, [키워드] 95% CI age antibody asked Belgium booster vaccination Care circulation cohort study Complete COVID-19 COVID-19 infection dominant eight eligible Epidemiology Follow-up general medicine (see internal medicine) Health Healthcare provider IgM and IgG incidence internal Longevity measure natural infection participant Participants participated Patient patients physically Prevalence primary care Prospective prospective cohort study provided questionnaire reached Receptor binding domain Registered SARS-CoV-2 SARS-CoV-2 antibody secondary outcome serological test supported vaccination variant virus women [DOI] 10.1136/bmjopen-2022-065897 PMC 바로가기
Understanding spatiotemporal symptom onset risk of Omicron BA.1, BA.2 and hamster-related Delta AY.127Article Published on 2022-09-162022-11-16 Journal: Frontiers in Public Health [Category] SARS, 변종, [키워드] acute respiratory syndrome Analysis booster booster vaccination concerning contribute contributed coronavirus country Delta dominant Effect faster full vaccination hamster-related Delta AY.127 help Hong Kong Identified increase in intrinsic Invasion investigation joint omicron Omicron BA.1 and BA.2 pandemic promote provide provided reduction reduction in reduction in area Region risk SARS-CoV-2 spatiotemporal spatiotemporal symptom onset risk. Spread symptom onset symptomatic symptomatic infections Transmissibility understanding vaccination vaccination rate variants variants of concern virus genomes [DOI] 10.3389/fpubh.2022.978052 PMC 바로가기
Regional importation and asymmetric within-country spread of SARS-CoV-2 variants of concern in the NetherlandsArticle Published on 2022-09-132022-11-15 Journal: eLife [Category] SARS, 변종, 치료기술, 치료제, [키워드] asymmetric Beta bidirectional caused circulating collected connection country COVID-19 Delta VOC dominant Effectiveness effort Epidemiology European Gamma global health highlight impacted Infection Infectious disease information International introduced Lineage Measures Microbiology National Netherland Netherlands occurred outbreak pandemic performed Phylogenetic analysis public health Region Regional robust SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 surveillance SARS-CoV-2 variant Spread Surveillance Transmission Travel variant viruses VoC VOCs [DOI] 10.7554/eLife.78770 PMC 바로가기
Surface Inactivation of Highly Mutated SARS-CoV-2 Variants of Concern: Alpha, Delta, and OmicronArticle Published on 2022-09-122022-11-16 Journal: Biomacromolecules [Category] SARS, 변종, [키워드] adaptive Alpha Antiviral Complete Degradation Delta dominant effective Evolution Face mask glycosylated inactivation independent induce Infection ingestion Mask mice mutations non-toxic omicron Omicron variant pandemic physical barrier Polymer reduction SARS-CoV-2 SARS-CoV-2 transmission Spike protein Spread surface Transmission Vaccine variant variants variants of concern viral genome viral membrane virion virulence virus VoC VOCs waning immunity [DOI] 10.1021/acs.biomac.2c00801 PMC 바로가기