Does lock-down of Wuhan effectively restrict early geographic spread of novel coronavirus epidemic during chunyun in China? A spatial model studyResearch Article Published on 2021-04-292022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, SARS, [키워드] absence Baidu baseline China Chunyun confirmed COVID-19 case coronavirus COVID-19 demonstrated distribution effective response Effectiveness Epidemic facilitated Geographic spread Impact less Lock-down majority Migration Novel coronavirus offset quantified restrict Result Spread spread of COVID-19 supported Travel Wuhan [DOI] 10.1186/s12889-021-10837-2 PMC 바로가기 [Article Type] Research Article
COVID-19 in Immunosuppressed ChildrenPediatrics Published on 2021-04-292022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] adaptive Autoimmune disease bat Cancer children clinical study competent coronavirus disease COVID-19 cytokine expression effective response element feature General population global pandemic hosts Hypothesis Immune-mediated Immunocompromised Immunosuppression Immunosuppressive medication Immunosuppressive treatment increased risk Infection Inflammasome innate immune system Innate immunity interferon kidney transplant liver transplant Manifestations mechanism mice multiorgan injury outcome over-inflammation pathogen clearance Patient pediatric phenotype populations pro-inflammatory signaling receiving reservoirs response rheumatologic diseases SARS-CoV-2 SARS-COV-2 infection SARS–CoV−2 severe COVID-19 Spread the disease the SARS-CoV-2 Tolerance Treatment type I viral clearance [DOI] 10.3389/fped.2021.629240 PMC 바로가기 [Article Type] Pediatrics
Shaping applied epidemiology workforce training to strengthen emergency response: a global survey of applied epidemiologists, 2019–2020Research Published on 2021-04-292022-10-31 Journal: Human Resources for Health [Category] Coronavirus, MERS, SARS, [키워드] Analysis applied basic competent conducted COVID-19 pandemic Critical cross-sectional demonstrated disseminate education effective effective response Emergencies Emergency emergency response English epidemiologists Epidemiology evaluate events field French Health health workforce identify International leadership less Local media outbreak participant Participants Pearson Program public health public health practice question Rapid reported respondent response Result shaping Surveillance survey training variables was used [DOI] 10.1186/s12960-021-00603-1 PMC 바로가기 [Article Type] Research
A small interfering RNA (siRNA) database for SARS-CoV-2Article Published on 2021-04-232022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 치료제, [키워드] Antiviral approaches binding characterized contributing to Coronavirus disease 2019 COVID-19 COVID-19 pandemic Data integration database databases dataset effective response evaluated faster Features global pandemic help Human genome information Laboratory Metadata nucleotide provided RNA RNA genome SARS-CoV-2 SARS-CoV-2 strains sequence siRNA table target target gene the SARS-CoV-2 thermodynamic [DOI] 10.1038/s41598-021-88310-8 PMC 바로가기 [Article Type] Article
The efficiency in the ordinary hospital bed management: A comparative analysis in four European countries before the COVID-19 outbreakResearch Article Published on 2021-03-222022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Analysis complex component Concentration country COVID-19 COVID-19 diffusion COVID-19 emergency COVID-19 outbreak Critical distribution effective response Efficacy Efficiency emergency situation Europe European country France Germany Health help hospital hospitalized patient Italy majority management occupancy rate Patient professionals reduced Region regions resource robust saturated significantly higher Spain Structure the epidemic [DOI] 10.1371/journal.pone.0248867 PMC 바로가기 [Article Type] Research Article
Efficacy and Effect of Inhaled Adenosine Treatment in Hospitalized COVID-19 PatientsImmunology Published on 2021-03-182022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] adenosine Antiviral treatment average COVID-19 COVID-19 patients COVID19 patient CRP level Cytokine storm decrease Effect effective response Efficacy high mortality rate Hospitalization immune system IMPROVE Inflammation Inflammatory mediators Inhaled Length of stay modulate NLR PaO parameters positive Prognosis progression reducing reduction reduction in Regulatory Safe SARS-CoV-2 Therapeutic treatment treated patient Treatment viral infection [DOI] 10.3389/fimmu.2021.613070 PMC 바로가기 [Article Type] Immunology
The prevalence and risk factors for depressive symptoms in frontline nurses under COVID-19 pandemic based on a large cross-sectional study using the propensity score-matched methodResearch Article Published on 2021-03-162022-10-27 Journal: BMC Psychiatry [Category] Coronavirus, COVID-19, SARS, [키워드] 95% confidence interval Characteristics collected conducted COVID-19 outbreak COVID-19 pandemic Critical cross-sectional demographics demonstrated Depression depressive symptom Depressive symptoms effective response enrolled Extensive Factor Factors independent risk factor involved Logistic regression mental health Nurse Nurses Odds ratio optimism participant physical activity Prevalence Protecting Psychological Psychological capital questionnaire Result risk factor Risk factors sleep quality Sleep quality, depression Specific Support [DOI] 10.1186/s12888-021-03143-z PMC 바로가기 [Article Type] Research Article
The prevalence and risk factors for depressive symptoms in frontline nurses under COVID-19 pandemic based on a large cross-sectional study using the propensity score-matched methodResearch Article Published on 2021-03-162022-10-27 Journal: BMC Psychiatry [Category] COVID-19, [키워드] 95% confidence interval Characteristics collected conducted COVID-19 outbreak COVID-19 pandemic Critical cross-sectional demographics demonstrated Depression depressive symptom Depressive symptoms effective response enrolled Extensive Factor Factors independent risk factor involved Logistic regression mental health Nurse Nurses Odds ratio optimism participant physical activity Prevalence Protecting Psychological Psychological capital questionnaire Result risk factor Risk factors sleep quality Sleep quality, depression Specific Support [DOI] 10.1186/s12888-021-03143-z PMC 바로가기 [Article Type] Research Article
Positive Environments and Precautionary Behaviors During the COVID-19 OutbreakPsychology Published on 2021-03-112022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] Behavior buffer can be used challenges COVID-19 COVID-19 pandemic effective response engage Environment Factor FIVE handling Health healthy include information Measures Mental Mexican pandemic participant participated physical positive positive environment precautionary Protective resource resources responsible self-care spread of COVID-19 stimulate Support wellbeing [DOI] 10.3389/fpsyg.2021.624155 PMC 바로가기 [Article Type] Psychology
Antibody Response to the BNT162b2 mRNA COVID-19 Vaccine in Subjects with Prior SARS-CoV-2 InfectionSARS-CoV-2 감염 이전에 BNT162b2 mRNA COVID-19 백신에 대한 항체 반응Clinical Trial Published on 2021-03-052022-08-13 Journal: Viruses [Category] SARS, 임상, 진단, [키워드] all subject all subjects analyzed Anti-spike anti-spike RBD IgG antibody antibody antibody levels Antibody Response Antibody titers BNT162b2 BNT162b2 mRNA BNT162b2 mRNA COVID-19 vaccine booster both groups control subject COVID-19 COVID-19 vaccine COVID-19 vaccines decrease develop domain effective response expected first dose Frequency healthcare worker IgG antibodies IgG antibody immune memory immune memory persist immune response immunogenicity individual induce infected individuals Infection local pain naïve individuals naïve subject naïve subjects natural infection Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers nine no significant difference not significantly different pre-existing immunity rapid increase RBD reactogenicity response SARS-CoV-2 SARS-COV-2 infection Side effects single dose subjects sustained the antibody response the vaccine titers vaccination Vaccine vaccine dose vaccine doses vaccine-associated side effects [DOI] 10.3390/v13030422 PMC 바로가기 [Article Type] Clinical Trial