SARS-CoV-2 infection dynamics in Denmark, February through October 2020: Nature of the past epidemic and how it may develop in the futureResearch Article Published on 2021-04-092022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] adjusted antibody assessment Asymptomatic average calculated Care contagious country Course COVID-19 COVID-19 epidemic COVID-19 pandemic death Denmark develop Diagnosis Epidemic error estimate evaluate expected Fatality rate Frequency General population Health Healthcare system hospital Hospitalization immunological include infected individual Infection initial Initially lock-down period majority mathematical National Nature occur occurred pandemic parameter Patient Population predicted Prevalence Rate Region Result robust SARS-COV-2 infection scaled shown Spain square Steady state symptomatic symptomatic and asymptomatic Symptoms the epidemic transmission rate Treatment USA [DOI] 10.1371/journal.pone.0249733 PMC 바로가기 [Article Type] Research Article
Hospital load and increased COVID-19 related mortality in IsraelArticle Published on 2021-03-262022-10-04 Journal: Nature Communications [Category] SARS, 치료법, [키워드] caused changes in Characteristics Computational models coronavirus disease 19 COVID-19 COVID-19 patient COVID-19 related mortality defined Epidemiology error Healthcare system hospital Hospitalized in-hospital mortality in-hospital mortality rate independent Ministry of Health moderate morbidity mortality rate Patient Patient care patients with COVID-19 SARS-CoV-2 significantly increased Spread Standard the patient Treatment viral infection [DOI] 10.1038/s41467-021-22214-z PMC 바로가기 [Article Type] Article
Clinical Trial Data Sharing for COVID-19–Related ResearchCOVID-19 관련 연구를 위한 임상 시험 데이터 공유Viewpoint Published on 2021-03-122022-09-10 Journal: Journal of Medical Internet Research [Category] SARS, 임상, [키워드] absence adjust approaches assessment assumption baseline bias challenge clinical Clinical research clinical trial clinical trials conducted control group cooperation COVID-19 COVID-19 pandemic Culture data data-sharing dataset Definition develop Diseases error event false-negative False-positive feasibility group heterogeneity Inconclusive interoperability Intervention lack likelihood linear Meta-analysis outcome measures outcomes pandemic Patient Perspective plethora privacy public health random-effect recruitment reductions in Registered registry reported Research risk factor sample size calculation Sample size calculations Scientific community security service statistical Statistical power statistically Structure total sample size Treatment Trial trials [DOI] 10.2196/26718 PMC 바로가기 [Article Type] Viewpoint
Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escapeSARS-CoV-2 스파이크 당단백질 드라이브 항체 탈출의 반복적인 결실Report Published on 2021-03-122022-09-10 Journal: Science (New York, N.y.) [Category] MERS, SARS, 변종, 진단, [키워드] accelerate acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive alteration Amino acid amino acids antibody antibody epitopes antigenic evolution antigenic sites antigenicity can not caused convergent evolution coronavirus defined Deletion Deletion variants deletions descendant descendants Epitopes error evade Evolution explain Genetic human host human populations human-to-human transmission immune pressure Immunity infected individual Infection Influenza influenza viruses initiated lineages Neutralizing antibodies overcome Pandemics persistent infection polymerase polymerases prevalent Proofreading RDR RDRs Recurrent Region related virus related viruses respiratory RNA viruses RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 genome Science severe acute respiratory syndrome Coronavirus spike glycoprotein Spike protein spike protein of SARS-CoV-2 Structure structures Substitution substitutions susceptible the SARS-CoV-2 the spike protein these viruses variant virus viruses [DOI] 10.1126/science.abf6950 PMC 바로가기 [Article Type] Report
COVID-19 mortality rate prediction for India using statistical neural networks and gaussian process regression modelArticles Published on 2021-03-012022-10-27 Journal: African Health Sciences [Category] COVID-19, [키워드] applied Basis Confirmed COVID-19 COVID-19 mortality dataset develop error evaluated function Generalized GPR GRNN GRP Hyperparameter tuning identify independent India mortality prediction mortality rate network Neural prediction Process Radial Rate RBFNN Regression Regression model regression models Research root Sery statistical time [DOI] 10.4314/ahs.v21i1.26 PMC 바로가기 [Article Type] Articles
COVID-19 mortality rate prediction for India using statistical neural networks and gaussian process regression modelArticles Published on 2021-03-012022-10-27 Journal: African Health Sciences [Category] Coronavirus, COVID-19, SARS, [키워드] applied Basis Confirmed COVID-19 COVID-19 mortality dataset develop error evaluated function Generalized GPR GRNN GRP Hyperparameter tuning identify independent India mortality prediction mortality rate network Neural prediction Process Radial Rate RBFNN Regression Regression model regression models Research root Sery statistical time [DOI] 10.4314/ahs.v21i1.26 PMC 바로가기 [Article Type] Articles
[Methods of SARS-CoV-2 detection in tissue][조직 내 SARS-CoV-2 검출 방법]Review Published on 2021-03-012022-09-11 Journal: Der Pathologe [Category] SARS, 치료기술, [키워드] alteration Antigen antigens approach Autopsies autopsy studies biopsies Chain Reaction choice COVID-19 COVID-19 patient curated database death detection diagnostic dominant electron electron microscopy English error evaluated feature fixation Fluorescence Fluorescence in situ hybridization histopathological finding immunofluorescence immunohistochemistry IMPROVE In situ hybridization information Interpretation interval less material Microscopy Morphological oder pathophysiology phase polymerase chain polymerase chain reaction preanalytical phase processing Protein reverse transcriptase Reverse transcriptase polymerase chain reaction RNA RT-PCR sample collection SARS-CoV-2 detection SARS-CoV‑2 sensitivity Sensitivity and specificity significantly higher source of error specificity surgical specimen surgical specimens the disease tissue tissues validation study [DOI] 10.1007/s00292-021-00919-8 PMC 바로가기 [Article Type] Review
Estimating the cumulative incidence of SARS-CoV-2 with imperfect serological tests: Exploiting cutoff-free approaches불완전한 혈청 검사로 SARS-CoV-2의 누적 발생률 추정: 차단 없는 접근 방식 활용Research Article Published on 2021-02-262022-09-12 Journal: PLoS Computational Biology [Category] MERS, 진단, [키워드] Accuracy antibody Antibody Response Antibody responses approach Asymptomatic asymptomatic infection Blood can be used circumvent confirmed case confirmed cases controls cumulative cumulative incidence Cutoff determine distribution elicit error estimate estimation False negative false negative results False positive fraction Guidance identify incidence individual individuals Infection leads less marker measure Measures Mild mixture model outperform pandemic parameter pathogen Pathogens Population Prevalence provided quantitative test required SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 pandemic SARS-CoV-2 specific antibodies SARS-CoV-2 specific antibody Sensitivity and specificity sera serological serological test Serological testing Serological tests seropositive seropositive individual seropositive individuals Serosurvey Serosurveys serum specific antibodies specific type specific types statistical statistical inference the SARS-CoV-2 to define yielding [DOI] 10.1371/journal.pcbi.1008728 PMC 바로가기 [Article Type] Research Article
Diagnostic bias during the COVID-19 era: COVID-19 or renal abscess?COVID-19 시대의 진단 편향: COVID-19 또는 신장 농양?Case Reports Published on 2021-02-072022-09-01 Journal: Urologia [Category] MERS, SARS, 진단, [키워드] abscess affected appear Case report chest CT scan coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 patient CT scan Diagnosis differential diagnosis discharged disease error fatigue Fever Health Organization hospital kidney tumor lead life-threatening Mild pandemic Patient performed positive swab presenting renal renal abscess SARS-CoV-2 Symptom Symptoms the patient treated Triage Tumor weight loss WHO World Health Organization [DOI] 10.1177/0391560321993592 PMC 바로가기 [Article Type] Case Reports
Interoperable Platform to Report Polymerase Chain Reaction SARS-CoV-2 Tests From Laboratories to the Chilean Government: Development and Implementation StudyOriginal Paper Published on 2021-01-202022-10-31 Journal: JMIR Medical Informatics [Category] COVID-19, [키워드] chain Chilean Community country COVID-19 COVID-19 pandemic defined develop development end point error generate Government HL7 FHIR implementation infected with SARS-CoV-2 information interoperability Isolation Laboratory laboratory information system lack management methodology Ministry of Health Notation object objective PCR platform polymerase chain positive Probability programming reaction reduce report Result SARS-CoV-2 SARS-CoV-2 test SARS-CoV-2 tests secure Test tested Testing was tested Web World Health Organization [DOI] 10.2196/25149 PMC 바로가기 [Article Type] Original Paper