Infectious viral shedding of SARS-CoV-2 Delta following vaccination: A longitudinal cohort studyArticle Published on 2022-09-122022-11-15 Journal: PLoS Pathogens [Category] SARS, 치료기술, [키워드] 95% CI Adults analyzed correlated Delta enrolled faster infections infectious titer Infectious virus longitudinal cohort study median nasal no difference participant Probability reduced RNA SARS-CoV-2 SARS-CoV-2 RNA specimen stratified symptom onset tested the median vaccination Viral RNA shedding viral shedding was reduced while [DOI] 10.1371/journal.ppat.1010802 PMC 바로가기
SARS-CoV-2 Production, Purification Methods and UV Inactivation for Proteomics and Structural StudiesArticle Published on 2022-09-082022-11-16 Journal: Viruses [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome biosafety can be used cell activation conditions core Coronavirus-2 COVID-19 died downstream effective experiments faster handling inactivated inactivation Laboratory Microscopy pandemic pathogenicity Production purification resulting SARS-CoV-2 Sequencing Seven significantly size exclusion structural studies. sucrose cushion ultracentrifugation UV inactivation virus [DOI] 10.3390/v14091989 PMC 바로가기
Right dose, right now: bedside, real-time, data-driven, and personalised antibiotic dosing in critically ill patients with sepsis or septic shock-a two-centre randomised clinical trialRandomized Controlled Trial Published on 2022-09-052022-10-05 Journal: Critical Care [Category] 임상, [키워드] Acute kidney injury Adequate Adult patient antibiotic Antibiotics clinical Clinical decision support clinical trial control group COVID-19 pandemic Critically ill patient critically ill patients data-driven dose Efficacy eligible Endpoint EudraCT European evaluate faster feasibility feasible for inclusion ICU implementation IMPROVE incidence Inclusion increased mortality Infection intervention group Lactate Mortality Netherland not significantly different outcome patients personalised pharmacokinetic pharmacokinetics Primary outcome randomisation randomised Registered renal right Safe Sepsis Septic shock significantly Support Therapeutic Drug Monitoring Trial was obtained [DOI] 10.1186/s13054-022-04098-7 PMC 바로가기 [Article Type] Randomized Controlled Trial
Anti-Inflammatory Activity of CIGB-258 against Acute Toxicity of Carboxymethyllysine in Paralyzed Zebrafish via Enhancement of High-Density Lipoproteins Stability and FunctionalityArticle Published on 2022-09-042022-11-15 Journal: International Journal of Molecular Sciences [Category] 진단, [키워드] activity aggregation ameliorated anti-inflammatory activity Autoimmune disease carboxymethyllysine (CML) cascade caused cholesterol CIGB-258 (Jusvinza) CML co-injection coronavirus disease COVID-19 cytokine Cytokine storm death death rate decrease developmental Efficacy Embryo enhancement exhibited faster ferrous ion Final HDL Heat shock high-density high-density lipoproteins (HDL) highest Hsp60 hyperinflammation infiltration Inflammation Inflammatory inflammatory cells infliximab inhibit injected injection kDa Ligand lipoprotein lowest mechanism neutrophil Pain paralysis Particle peptide plasma protective effect Protein resulting stability Stress Survivability systemic inflammation tissue treated Triglyceride was tested zebrafish [DOI] 10.3390/ijms231710130 PMC 바로가기
Influence of Effort-based Reward Training on Neuroadaptive Cognitive Responses: Implications for Preclinical Behavioral Approaches for Depressive SymptomsResearch article Published on 2022-09-012022-10-05 Journal: Neuroscience [Category] 비임상, [키워드] approach approaches assigned BDNF brain-derived neurotrophic factor (BDNF) cognitive Dehydroepiandrosterone (DHEA) depressive depressive symptom Depressive symptoms disorder Efficacy Effort-based Reward (EBR) examination exhibited faster female group immunoreactivity incidence rate influence lack Lateral habenula (LHb) male males mechanism mechanisms no significant effect offer Preclinical Preclinical model of depression prevented provide response therapeutic intervention Therapies training Trial trials were assessed [DOI] 10.1016/j.neuroscience.2022.08.002 [Article Type] Research article
Evaluation of a new “all in one” SARS-CoV-2 antigen-detecting rapid diagnostic test and self-test: Diagnostic performance and usability in child and adult populations새로운 "올인원" SARS-CoV-2 항원 검출 신속 진단 테스트 및 자가 테스트 평가: 어린이 및 성인 인구의 진단 성능 및 유용성Multicenter Study Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] Adults age Antigen antigen testing Chain Reaction children children COVID testing classic COVID COVID-19 diagnostic diagnostic test diagnostic testing diagnostic tests Epidemics evaluate evaluated faster Health health priorities investigated less majority multicenter multicenter study multiplex nasal Nasal sampling nasal swab nasopharyngeal sample Nasopharyngeal samples Other respiratory viruses participant performed Perspective point-of-care polymerase chain polymerase chain reaction Population Rapid diagnostic test respiratory infections respiratory viruses reverse transcriptase Reverse transcriptase polymerase chain reaction risk RT-PCR Saliva SARS-CoV-2 Self-test specificity switching transcriptase trauma Usability [DOI] 10.1002/jmv.27812 PMC 바로가기 [Article Type] Multicenter Study
Effectiveness of rapid antigen testing for screening of asymptomatic individuals to limit the transmission of SARS-CoV-2: A rapid reviewArticle Published on 2022-09-012022-11-15 Journal: Reviews in Medical Virology [Category] SARS, 치료기술, [키워드] Antigen antigen detection Asymptomatic asymptomatic individual Asymptomatic individuals Care Cochrane Library COVID-19 Effectiveness Europe Evidence examined faster good quality Google Scholar Isolation limit Methodological quality offer PMC polymerase chain positive quarantine Rapid rapid testing required Research reverse transcription RT-PCR SARS-CoV-2 Schools Screening Study design Surveillance Transmission transmission of SARS-CoV-2 widespread [DOI] 10.1002/rmv.2350 PMC 바로가기
Rapid and qualitative identification of SARS-CoV-2 mutations associated with variants of concern using a multiplex RT-PCR assay coupled with melting analysisArticle Published on 2022-09-012022-11-16 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] amplified Analysis Beta characterized Complete Concordance contributing to Delta detect Direct E484K examined expected faster Gamma Genetic variant L452R melting Melting analysis multiplex Mutation mutations N501Y Nasopharyngeal swab nasopharyngeal swabs omicron positive public health Rapid Rapid identification RT-PCR RT-PCR assay Sanger method Sanger sequencing SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 variants sensitivity Sensitivity and specificity Seven specificity Spread Surveillance the SARS-CoV-2 variant variants of concern Viral load was performed [DOI] 10.1016/j.ijid.2022.06.032 PMC 바로가기
Abbott® ID NOW™ COVID-19 rapid molecular assay versus Hologic® Panther Aptima™ SARS-CoV-2 assay in nasopharyngeal specimens: results from 1-year retrospective study in an emergency department비인두 표본에서 Abbott® ID NOW™ COVID-19 Rapid 분자 분석 대 Hologic® Panther Aptima™ SARS-CoV-2 분석: 응급실에서 1년 후향적 연구 결과Article Published on 2022-09-012022-09-11 Journal: Diagnostic microbiology and infectious disease [Category] COVID19(2023년), SARS, 치료기술, [키워드] Care COVID-19 Device emergency department facilitate faster Hologic Panther Point of care device ID NOW implementation infection control Measures molecular nasopharyngeal Patient Point positive Retrospective study SARS-CoV-2 [DOI] 10.1016/j.diagmicrobio.2022.115742 PMC 바로가기 [Article Type] Article
Directional mutation and crossover boosted ant colony optimization with application to COVID-19 X-ray image segmentationResearch article Published on 2022-09-012022-10-05 Journal: Computers in biology and medicine [Category] 변종, 치료기술, [키워드] Accuracy ACO Algorithm Ant colony optimization competing COVID-19 COVID-19 X-ray directional ENhance experiment experiments faster Image segmentation IMPROVE increase Local Mutation optimization Other Swarm intelligence threshold two-dimensional Validity were used X-ray [DOI] 10.1016/j.compbiomed.2022.105810 [Article Type] Research article