Diagnosis of Feline Infectious Peritonitis: A Review of the Current LiteratureReview Published on 2019-11-152022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Abnormalities antibody change Clinical practice Clinical sign coronavirus current definitive diagnosis Diagnosis diagnostic diagnostic methods diagnostic test facilitate fatal disease Feline infectious peritonitis FIP help ICC IHC immunocytochemistry immunohistochemistry Interpretation Laboratory limitations literature non-specific performed raise reported review RT-PCR Sensitivity and specificity virulence virus [DOI] 10.3390/v11111068 PMC 바로가기 [Article Type] Review
Mucosal Immune Response to Feline Enteric Coronavirus InfectionArticle Published on 2019-09-272022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] abnormality biopsy caused collected Colon Control convalescent coronavirus enteric expression fatal disease fecal Fecal sample feline enteric coronavirus Feline infectious peritonitis groups histologic humoral IFNγ IgG Infection inflammatory state investigated lymphocyte subpopulation mucosa mucosal mucosal IgA response mucosal immune mucosal immunity mutant virus organ pathogenic Perturbation phenotype proliferation response Result Significant suggested T cell three groups virus virus clearance [DOI] 10.3390/v11100906 PMC 바로가기 [Article Type] Article
Characterization of antiviral T cell responses during primary and secondary challenge of laboratory cats with feline infectious peritonitis virus (FIPV)Research Article Published on 2019-05-222022-10-28 Journal: BMC veterinary research [Category] Coronavirus, MERS, [키워드] acute infection adaptive Antiviral Antiviral T cell responses Blood Cell-mediated immunity cellular immunity characterization Clinical outcome demonstrated develop difference disease Disease progression early phase early stage experimental group Feline infectious peritonitis Feline infectious peritonitis virus healthy Host Immunity implicated Infection Interaction Laboratory later phase Lymph node lymphocyte outcome pathogen pathogenic Predictive Primary infection progression proliferation provided Result robust SPF subset suggested survived T cell T cell depletion T cell response T cell subset tested viral antigens virus WBC White blood cell [DOI] 10.1186/s12917-019-1909-6 PMC 바로가기 [Article Type] Research Article
Preliminary investigation on feline coronavirus presence in the reproductive tract of the tom cat as a potential route of viral transmissionOriginal Articles Published on 2019-03-222022-10-29 Journal: Journal of Feline Medicine and Surgery [Category] Coronavirus, MERS, [키워드] appear association Blood blood sample cattery management Contact coronavirus correlated disorder Feline coronavirus Feline infectious peritonitis histology immune-mediated disease immunohistochemistry Infection initiated male molecular objective PCR performed positive prevention Probability quantitative PCR reproductive Result reverse transcriptase PCR RT-PCR RT-qPCR Semen Semen samples Seroconversion serology serum serum sample serum samples testicle tom cat reproduction transcriptase Transmission unlikely Viral load Viral RNA Viral transmission virus was performed [DOI] 10.1177/1098612X19837114 PMC 바로가기 [Article Type] Original Articles
Reverse Genetics for Type I Feline Coronavirus Field Isolate To Study the Molecular Pathogenesis of Feline Infectious PeritonitisResearch Article Published on 2018-07-312022-10-29 Journal: mBio [Category] Coronavirus, MERS, [키워드] acquisition can be used caused Cell cell culture system coronavirus Course Culture facilitate feline coronavirus field isolates Feline infectious peritonitis field function gene product genetic change genetic manipulation genetics Genome in vitro in vivo Infection infections isolate knowledge lack less lethal infection molecular Mutation other coronavirus Pathogenesis peritonitis predicted previous study progression of disease provide Research responsible reverse genetics RNA virus serotype shown specific mutations strain subsequent suggested Type virus virus stock [DOI] 10.1128/mBio.01422-18 PMC 바로가기 [Article Type] Research Article
Nanoparticulate vacuolar ATPase blocker exhibits potent host-targeted antiviral activity against feline coronavirusArticle Published on 2017-10-122022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] addition administration Alter Antibody-dependent enhancement antiviral activity Antiviral effect ATPase caused cells cellular coronavirus cytoplasmic disease downstream effective Endosomal acidification exhibit Experimental result Feline infectious peritonitis High-dose highlight in vitro model incurable Infection inhibit inhibitory activity intravenous investigated mechanism mice mutated pathogenic safety profile susceptibility therapeutic potential Treatment Vaccine vacuolar viral disease virus virus replication [DOI] 10.1038/s41598-017-13316-0 PMC 바로가기 [Article Type] Article
Limitations of using feline coronavirus spike protein gene mutations to diagnose feline infectious peritonitisResearch Article Published on 2017-10-052022-10-28 Journal: Veterinary Research [Category] Coronavirus, [키워드] Analysis Antigen coronavirus coronavirus spike protein determine diagnose Diagnosis faece Faeces fatal disease Feline infectious peritonitis gene mutation healthy histopathological identification immunohistochemistry implicated IMPROVE Infection limitation mutated Mutation positive Post-mortem Primers purified RNA RT-qPCR S gene Sample sensitivity Sequencing specificity Spread supplementary material tissue tissue sample viral spike was performed [DOI] 10.1186/s13567-017-0467-9 PMC 바로가기 [Article Type] Research Article
Identification and characterization of a Golgi retention signal in feline coronavirus accessory protein 7bResearch Article Published on 2017-08-312022-10-30 Journal: The Journal of General Virology [Category] Coronavirus, MERS, [키워드] accessory protein addition approach C-terminal C-terminus cause cells cellular cellular trafficking changes in cleavage site Control coronavirus coronavirus accessory proteins Effect Endoplasmic reticulum expressing expression Feline coronavirus Feline infectious peritonitis FIVE FLAG-tagged form functions Genetic glycosylation Golgi Golgi retention identification information investigated motif mutant N-terminal predicted processed Protein Proteins provide purified recombinant residues resulting retained retention signal reverse genetics secretion sequence Sequence analysis Substitution virus [DOI] 10.1099/jgv.0.000879 PMC 바로가기 [Article Type] Research Article
Feline coronavirus replication is affected by both cyclophilin A and cyclophilin BResearch Article Published on 2017-02-132022-10-30 Journal: The Journal of General Virology [Category] Coronavirus, [키워드] active site active sites affected affinity Alter analysed Animal coronaviruses cause Cell cells coronavirus Coronavirus replication cyclophilin cyclosporin effective vaccine expressed fatal disease Feline coronavirus Feline infectious peritonitis in vitro in vivo incurable inhibit inhibited inhibition inhibitor knockdown less mechanism Mutation peptidyl-prolyl cis-trans isomerase predicted Protein reduced Regulation Replication required Treatment [DOI] 10.1099/jgv.0.000663 PMC 바로가기 [Article Type] Research Article
Feline Coronavirus 3c Protein: A Candidate for a Virulence Marker?Research Article Published on 2016-05-032022-10-27 Journal: BioMed Research International [Category] Coronavirus, MERS, [키워드] addition asymptomatic infections candidate cause clone coronavirus demonstrated fatal disease Feline infectious peritonitis genetic diversity genetic marker M gene marker mutant spectrum producing Protein responsible sequenced strain suggested unique virulent virus widespread [DOI] 10.1155/2016/8560691 PMC 바로가기 [Article Type] Research Article