Profiling of Substrate Specificities of 3C-Like Proteases from Group 1, 2a, 2b, and 3 CoronavirusesResearch Article Published on 2011-11-022022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] 3CL pro acute respiratory syndrome Betacoronavirus cleaved coronavirus correlated CoV CoVs different finding Gln group human CoV hydrophobic residue hydrophobicity IBV Infection Infectious Bronchitis Virus inhibitor NL63 OC43 polyprotein Profiling protease Proteases protein sequences Proteolytic processing residue residues SARS-CoV secondary structure sequence similarity Specificities specificity structural property Substitution substrate variant viral replication Volume [DOI] 10.1371/journal.pone.0027228 PMC 바로가기 [Article Type] Research Article
Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike proteinArticle Published on 2006-04-172022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] affected Anti-viral antiviral activity Asia Atypical cell cytotoxicity Class I viral fusion protein Concentration concentrations coronavirus CoV domain dose-dependent Effect Europe fusion peptide fusion protein glycoprotein heptad repeat hydrophobicity IC50 identify inhibited inhibition inhibitor membrane membrane fusion MHV murine hepatitis virus N-terminus North America peptide Peptide inhibitor Pneumonia provide recent Receptor binding Region regions responsible S2 subunit SARS-CoV severe Severe acute respiratory syndrome-associated coronavirus six-helix bundle tested the S protein viral infectivity viral spike viral spike protein was used white [DOI] 10.1016/j.virusres.2006.03.001 PMC 바로가기 [Article Type] Article
Molecular analysis of the S1 subunit of the spike glycoprotein of respiratory and enteric bovine coronavirus isolatesArticle Published on 2002-01-302022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] Allelic variation alteration Amino acid amino acid change amino acid substitution Analysis analyzed antigenic Bovine coronavirus Characteristics classical cleavage site Clustering compared diarrhea different Genetic group hydrophobicity isolate isolates led to nucleotide Phylogenetic analysis polymorphism predicted Probability Protein residue Respiratory and enteric BoCV S glycoprotein S1 subunit secondary structure sequence Sequencing significant changes in spike glycoprotein strain Strains the S1 subunit two subgroups variations [DOI] 10.1016/S0168-1702(02)00004-7 PMC 바로가기 [Article Type] Article