Risk Diagrams Based on Primary Care Electronic Medical Records and Linked Real-Time PCR Data to Monitor Local COVID-19 Outbreaks During the Summer 2020: A Prospective Study Including 7,671,862 People in Catalonia2020년 여름 동안 지역 COVID-19 발병을 모니터링하기 위한 1차 진료 전자 의료 기록 및 연결된 Real-Time PCR 데이터를 기반으로 하는 위험 다이어그램: 카탈로니아의 7,671,862명을 포함한 전향적 연구Public Health Published on 2021-07-052022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 치료기술, [키워드] 95% confidence interval Admission Care CMAs Cohort community transmission COVID-19 cumulative Diagram effective electronic medical record EMR estimate growth hospital Hospital admissions Hospitalization ICU ICU admission ICU admissions incidence Including Increases increases in Increasing intensive care interquartile range Local local outbreak local outbreaks management Measures median medical records monitoring Mortality nursing home outbreak outbreak detection PCR PCR tests PCR-confirmed PCRs population-based cohort Precision primary care Prospective provided public health Record sentinel subsequent summer Surveillance Transmission was obtained Weekly were excluded [DOI] 10.3389/fpubh.2021.693956 PMC 바로가기 [Article Type] Public Health
Renin-angiotensin system inhibitors effect before and during hospitalization in COVID-19 outcomes: Final analysis of the international HOPE COVID-19 (Health Outcome Predictive Evaluation for COVID-19) registryObservational Study Published on 2021-07-012022-10-04 Journal: American heart journal [Category] SARS, 임상, [키워드] adjusted Admission all-cause mortality Analysis Comorbidity complications coronavirus disease COVID-19 COVID19 dead death discharged eligible event heart failure high-risk population hospital Hospitalization hospitalized COVID-19 patients ICU admission ICU admissions In-hospital inhibitor International investigator-initiated Italy less male mechanical ventilation Mortality Older outcomes Patient patients Probability receiving renal Sepsis significantly SIRS Spain survival target receptor Treatment with COVID-19 worse prognosis [DOI] 10.1016/j.ahj.2021.04.001 PMC 바로가기 [Article Type] Observational Study
The protective association between statins use and adverse outcomes among COVID-19 patients: A systematic review and meta-analysisResearch Article Published on 2021-06-242022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Administered Admitted Patient adverse outcome adverse outcomes analyzed association cohorts COVID-19 COVID-19 diagnosis COVID-19 hospitalization COVID-19 patient Cytokine storm did not reduce hazard ratio ICU ICU admissions identify individual literature lower risk mechanical ventilation mechanism Meta-analysis Mortality non-ICU non-ICU patients Odds ratio patients Protective reduce reported Result risk searched Severe COVID-19 pneumonia statin subgroup systematic review [DOI] 10.1371/journal.pone.0253576 PMC 바로가기 [Article Type] Research Article
Diabetes and COVID19: a bidirectional relationshipMini Review Published on 2021-06-232022-10-31 Journal: European journal of clinical nutrition [Category] COVID-19, MERS, SARS, [키워드] addition bidirectional relationship clinical care Comorbidity coronavirus Corticosteroid Course COVID19 Cytokine storm demonstrated diabete diabetes Diabetes complications drug glycemic control healthy hyperglycemia ICU admissions increased risk Infection insulin lockdowns mechanical ventilation medication Mild Mortality MOST outcome outcomes pancreatic damage pandemic Patient public health measure severe disease Spread Stress switching Treatment virus while worsening [DOI] 10.1038/s41430-021-00961-y PMC 바로가기 [Article Type] Mini Review
Diabetes and coronavirus (SARS-CoV-2): Molecular mechanism of Metformin intervention and the scientific basis of drug repurposing당뇨병 및 코로나바이러스(SARS-CoV-2): 메트포르민 개입의 분자 메커니즘 및 약물 용도 변경의 과학적 근거Review Published on 2021-06-222022-09-10 Journal: PLoS Pathogens [Category] MERS, 신약개발, 치료제, [키워드] acute respiratory syndrome coronavirus administration adverse outcomes affected Anti-inflammatory antidiabetic drug Antidiabetic drugs antioxidant Antiviral blood glucose Cardiopulmonary caused complications contribute coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patients detrimental effect detrimental effects Diabetic disease severity Effect explain Glucose ICU admissions immunomodulatory increased risk individual individuals insulin Intervention maintaining mechanism metformin molecular mechanism molecular mechanisms Mortality mortality rate new strain new strain of coronavirus pandemic reduced reduction in respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Treatment Vascular WHO [DOI] 10.1371/journal.ppat.1009634 PMC 바로가기 [Article Type] Review
Safety and efficacy of Favipiravir in moderate to severe SARS-CoV-2 pneumonia중등도에서 중증 SARS-CoV-2 폐렴에서 Favipiravir의 안전성 및 효능Randomized Controlled Trial Published on 2021-06-012022-09-11 Journal: International immunopharmacology [Category] 임상, 치료제, [키워드] 95% CI Adding addition changes in Chest chest computerized tomography scan clinical clinical recovery clinical trial Computerized tomography COVID19 CT scan deaths did not reduce Efficacy enrolled examined Favipiravir ground glass group groups Hospital mortality Hospital stay Hydroxychloroquine ICU admission ICU admissions in-hospital mortality Infection intubation intubations less Lopinavir Lopinavir/ritonavir mean hospital stay moderate moderate to severe Mortality multicenter not different not significantly different oxygen oxygen saturation Patient Pneumonia quantified Randomized Randomly regimen Ritonavir Safety SARS-CoV-2 Severe case severe SARS-CoV-2 standard care supplemental oxygen time Treatment Treatment protocol treatment regimen treatment regimens two groups [DOI] 10.1016/j.intimp.2021.107522 PMC 바로가기 [Article Type] Randomized Controlled Trial
A Discrete-Event, Simulated Social Agent-Based Network Transmission (DESSABNeT) model for communicable diseases: Method and validation using SARS-CoV-2 data in three large Australian citiesResearch Article Published on 2021-05-212022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] agent behavioural coast Combination communicable complex Contact tracing contribute COVID-19 vaccine died disease disease transmission epidemiological gold Health Service hospital hospitalisation ICU admissions Importance incidence incidence of COVID-19 Interaction Melbourne Model network novel virus objective outcome Pandemics physical distancing platform predict predicted Result SARS-CoV-2 spread of COVID-19 vaccination [DOI] 10.1371/journal.pone.0251737 PMC 바로가기 [Article Type] Research Article
The Use of Venovenous Extracorporeal Membrane Oxygenation in COVID-19 Infection: One Region’s Comprehensive ExperienceObservational Study Published on 2021-05-012022-10-04 Journal: ASAIO journal (American Society for Artificial Int [Category] SARS, 임상, [키워드] 95% CI acute respiratory distress ARDS Care center cohort study Comprehensive coronavirus disease COVID-19 COVID-19 case COVID-19 hospitalization COVID-19 infection demonstrated described discharge ECMO evaluated expected experience Extracorporeal extracorporeal membrane oxygenation Frequency highest hospital ICU ICU admissions ICU patient Infection Intensive intensive care Intervention intubation LOS management outcome Patient patients with ARDS Pneumonia positive recent Region resource secondary selected severe ARDS study period Support supported survival survived syndrome the patient V-V ECMO with COVID-19 [DOI] 10.1097/MAT.0000000000001403 PMC 바로가기 [Article Type] Observational Study
Global Sex Disparity of COVID-19: A Descriptive Review of Sex Hormones and Consideration for the Potential Therapeutic Use of Hormone Replacement Therapy in Older AdultsReview Published on 2021-04-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] Adults adverse effect adverse outcomes affected age and sex approved Care clinical trial confirmed case Coronavirus-2 COVID-19 death disparity drug elderly patients Evidence FDA food healthcare hormone hospitalizations hospitals ICU admissions immune system knowledge male Older Older adults outcome pandemic Patient performed positive Potential progesterone reducing replacement review SARS-CoV-2 SARS-COV-2 infection Sex sex hormone Sex hormones sexual disparity significantly stages Steroids therapeutic option treating COVID-19 vaccine for COVID-19 [DOI] 10.14336/AD.2020.1211 PMC 바로가기 [Article Type] Review
Characteristics and comparative clinical outcomes of prisoner versus non-prisoner populations hospitalized with COVID-19Article Published on 2021-03-222022-10-04 Journal: Scientific Reports [Category] SARS, 임상, [키워드] 30-Day mortality 95% CI 95% confidence interval adjusted age clinical Clinical outcome Cohort confirmed case COVID-19 COVID-19 case Diseases elevated Fever hazard ratio Henry Ford hospital Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients Hypoxemia ICU ICU admissions In-hospital death in-hospital mortality incarcerated individuals inflammatory markers intensive care Intubated intubation Intubation rates Logistic regression males Medical research Mortality Odds ratio outcome patients patients hospitalized paucity of data Population Primary outcome Primary outcomes prison Prisoner required Risk factors System tachypnea the United State Vasopressor were used with COVID-19 [DOI] 10.1038/s41598-021-85916-w PMC 바로가기 [Article Type] Article