Immunomodulation Induced During Interferon-α Therapy Impairs the Anti-HBV Immune Response Through CD24 + CD38 hi B CellsOriginal Research Published on 2020-12-232023-06-03 Journal: Frontiers in Immunology [Category] B형 간염, Fulltext, [키워드] anti-virus function CD24+CD38hi B Chronic hepatitis B virus infection immunomodulatory effects Peg-IFNα-2b [DOI] 10.3389/fimmu.2020.591269 PMC 바로가기 [Article Type] Original Research
Role of Host Immune and Inflammatory Responses in COVID-19 Cases with Underlying Primary Immunodeficiency: A Review기저 면역 결핍이 있는 COVID-19 사례에서 숙주 면역 및 염증 반응의 역할: 검토Review Published on 2020-12-012022-09-12 Journal: Journal of interferon & cytokine research : the of [Category] MERS, 진단, [키워드] acute respiratory syndrome anti-infection Anti-inflammatory Antiviral characterized Comorbidities coronavirus Coronavirus disease 2019 COVID-19 cytokine release Cytokine release syndrome Cytokine storm Cytokine storm syndrome deficiency disease severity higher risk IFNAR2 Immune status immune system immunodeficiency immunomodulatory effects Inflammatory response innate immune innate immune activation Innate immunity interferon regulatory factor interferon signaling Intravenous immunoglobulin IVIG literature review outcome pandemic Patient patient population patients PID Primary Immunodeficiency protective effect protective factor question receptor response review role SARS-CoV-2 SARS-COV-2 infection severe COVID-19 severe infections Signaling Spread suppressed susceptible therapy TLR7 [DOI] 10.1089/jir.2020.0210 PMC 바로가기 [Article Type] Review
Garlic ( Allium sativum L.): a potential unique therapeutic food rich in organosulfur and flavonoid compounds to fight with COVID-19마늘( Allium sativum L.): COVID-19와 싸울 수 있는 유기황 및 플라보노이드 화합물이 풍부한 잠재적인 독특한 치료 식품Letter to the Editor Published on 2020-11-182022-08-31 Journal: Nutrition Journal [Category] 치료제, [키워드] accelerated active site adjuvant therapy Allicin alliin Allium Antibiotics Antiviral Bacteria Compound coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 outbreak COVID-19 pandemic dietary intake dose flavonoid Garlic Health Health crisis healthy hydrogen Hydrogen bond hydrogen bonds immunomodulatory effect immunomodulatory effects IMPROVE inhibit protease quercetin reducing Region responsible SARS-CoV-2 Serine Side effect Side effects spice therapeutic therapeutic drug therapy Toxicity unique Viral viral replication virus viruses with COVID-19 [DOI] 10.1186/s12937-020-00643-8 PMC 바로가기 [Article Type] Letter to the Editor
Physical Exercise as a Multimodal Tool for COVID-19: Could It Be Used as a Preventive Strategy?Review Published on 2020-11-172022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] acute respiratory syndrome anti-inflammatory properties China chronic disease clinical trials Cluster complementary Control coronavirus coronavirus disease COVID-19 COVID-2019 drug effective therapy Efficacy and safety ENhance etiology exercise Health care Human immune protection immune system immunological immunomodulatory effects implementation IMPROVE Inflammation microbial infection modulate nitric oxide Novel coronavirus oxidative stress Pathways Patient physical Physical exercise Pneumonia Quality of life reported SARS-CoV-2 SARS-CoV-2 drug SARS-CoV-2 virus infection stimulate Treatment World Health Organization [DOI] 10.3390/ijerph17228496 PMC 바로가기 [Article Type] Review
Mesenchymal stem cell therapies for COVID-19: Current status and mechanism of actionArticle Published on 2020-09-232023-06-15 Journal: Life sciences [Category] MERS, SARS, [키워드] Cell therapy clinical trials coronavirus Cytokine storm immunomodulatory effects [DOI] 10.1016/j.lfs.2020.118493 PMC 바로가기 [Article Type] Article
Statin Use Is Associated with Decreased Risk of Invasive Mechanical Ventilation in COVID-19 Patients: A Preliminary StudyArticle Published on 2020-09-172022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] adjusted Admission Affect age Analysis analyzed Anti-inflammatory association associations cardiovascular disease chronic pulmonary disease Comorbidity conducted confidence Course COVID-19 COVID-19 patient CVD Decreased demographics diabetes HMG-CoA HMG-CoA reductase inhibitors hospital Hospitalization hospitalized patients ICU immunomodulatory effects implication IMV In-hospital death inhibitor intensive care interval Invasive mechanical ventilation management Mechanical medication medications multivariate logistic regression obesity outcome past medical history Patient patients hospitalized performed pleiotropic Prospective Study Ratio retrospective cohort study Rhode Island risk SARS-CoV2 severe COVID-19 Sex significantly statin statins Support USA were recorded with COVID-19 [DOI] 10.3390/pathogens9090759 PMC 바로가기 [Article Type] Article
Subcutaneous administration of interferon beta-1a for COVID-19: A non-controlled prospective trialArticle Published on 2020-06-072022-10-04 Journal: International immunopharmacology [Category] MERS, SARS, 임상, [키워드] administration Adverse drug reaction age Antiviral clearance clinical Clinical symptoms Combination coronavirus country COVID-19 death demographic dose Effect Epidemic evaluate Hospitalization Hydroxychloroquine imaging immunomodulatory effects include infected cells interferon Interferon beta-1a interferons management maturation New coronavirus Patient patients previous study Prospective trial protein synthesis Pulmonary infection recorded resolved Result Seven shown significant decrease Spread subcutaneous administration subcutaneously Support susceptible Symptom the patient therapeutic effect therapy Trial Trial registration viral replication virological clearance virus [DOI] 10.1016/j.intimp.2020.106688 PMC 바로가기 [Article Type] Article
MSC Therapies for COVID-19: Importance of Patient Coagulopathy, Thromboprophylaxis, Cell Product Quality and Mode of Delivery for Treatment Safety and EfficacyImmunology Published on 2020-05-192022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, [키워드] acute respiratory distress adaptive approved ARDS Blood cause Cell cellular characterized clinical guideline clinical trial coagulation/clotting/thrombosis coronavirus-induced disease 2019 (COVID19) COVID-19 COVID-19 patient COVID-19 patients criteria Critical Critically ill delivery disease Disseminated intravascular coagulation effective effective therapy Express expression fatality hemocompatibility testing high risk hypercoagulable immune immunomodulatory effects Importance Inflammation intensive care unit (ICU) intravascular and intravenous infusion intravenous IV infusion mesenchymal stromal cells (MSC) mitigate mode Mortality MSC MSC therapy MSCs multi-organ failure Numerous organ Patient patient population Pneumonia procoagulant procoagulant tissue factor product promote Quality Registered risk robust Safe Safety safety profile Sepsis severe acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2) shown syndrome Therapies therapy Thromboembolism thrombotic tissue tissue factor (TF/CD142) tissue repair Treatment while [DOI] 10.3389/fimmu.2020.01091 PMC 바로가기 [Article Type] Immunology
Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 feeding enhances humoral immune responses, which are suppressed by the antiviral neuraminidase inhibitor oseltamivir in influenza A virus-infected miceArticle Published on 2019-11-012023-06-24 Journal: Journal of dairy science [Category] 신종인플루엔자, [키워드] immunomodulatory effects influenza A virus infection oseltamivir yogurt culture. [DOI] 10.3168/jds.2019-16268