Computational characterization of inhaled droplet transport to the nasopharynxArticle Published on 2021-03-232022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] airway biomedical engineering COVID-2019 determine distribution domain droplet Fluid dynamics help hospitalized COVID-19 patient Infection infectious dose Inhaled initial nasopharyngeal nasopharynx proceed question Respiratory tract diseases reveal sputum subject susceptibility the disease the SARS-CoV-2 Translational research Transmission transmission of SARS-CoV-2 Transport virion [DOI] 10.1038/s41598-021-85765-7 PMC 바로가기 [Article Type] Article
Puerarin enhances intestinal function in piglets infected with porcine epidemic diarrhea virusArticle Published on 2021-03-222022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] 16S rRNA activity addition Administered alanine aminotransferase alkaline phosphatase alleviate Anti-inflammatory antimicrobial agent antioxidant applied Aspartate aminotransferase Blood caecum Clostridium collected Concentration Culture determine diamine oxidase dismutase dosage Drug discovery ENhance Enterobacteriaceae Enterococcus epidemic diarrhea fatty Heat shock hydrogen peroxide Infection infectious dose inoculated interleukin-6 intestinal intestinal injury intestine lactobacillus Microbiology Molecular biology morbidity mRNA level myeloperoxidase Neutrophils nuclear PEDV peroxidase plasma plasma concentration Protein protein concentration puerarin reduced reported Result serum TCID tissue Trial tumor necrosis factor-α virus White blood cell [DOI] 10.1038/s41598-021-85880-5 PMC 바로가기 [Article Type] Article
Indoor Model Simulation for COVID-19 Transport and ExposureArticle Published on 2021-03-122022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] acute respiratory syndrome aerosol airways Combined complex coronavirus Correcting COVID-19 distribution dose expiratory droplet exposure female indoor aerosol modeling Infection infectious dose inhalation Inhaled inhaled dose male Model novel coronavirus disease Particles recipients reduced respiratory tract respiratory virus risk SARS-CoV-2 Simulation susceptible Transmission Transport Ventilated Ventilation virus [DOI] 10.3390/ijerph18062927 PMC 바로가기 [Article Type] Article
Rapid Assessment of SARS-CoV-2 Transmission Risk for Fecally Contaminated River WaterArticle Published on 2021-02-222022-10-28 Journal: ACS Es&t Water [Category] COVID-19, [키워드] acute respiratory syndrome approach approaches assessment available data Contaminated coronavirus country Critical decrease Dilution droplet Epidemiology example Fecal–oral transmission fecal−oral identifying in vitro data infection rate infectious dose outbreak Outbreaks Rapid recommendation Research risk risk of transmission river SARS-CoV-2 sewage survival temperature Transmission transmission route used to evaluate Viral load water water transmission [DOI] 10.1021/acsestwater.0c00246 PMC 바로가기 [Article Type] Article
Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infectionResearch Article Published on 2020-12-252022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] adaptive age approved caused Course COVID-19 COVID-19 patients death disease Disease model FIVE hamster immune Infection infection model infectious dose interleukin 2 intranasal lung Mild moderate pandemic Particles Pneumonia receptor responsible SARS-CoV-2 SARS-COV-2 infection Severity of disease Sex Spread susceptibility susceptible Treatment Vaccine viral persistence virus [DOI] 10.1080/22221751.2020.1858177 PMC 바로가기 [Article Type] Research Article
Assessment of Air Contamination by SARS-CoV-2 in Hospital SettingsResearch Published on 2020-12-232022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome analyzed article assessment Care Concentration conducted Contamination coronavirus coronavirus disease cross-sectional Culture cultures database described distill distribution equipment Evidence extension Factor finding greater high viral load hospital Importance infectious dose intensive care interquartile range item less median no difference objective observational study Particle Patient patients performed Point positive Relevance Reporting review SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 viral RNA setting significantly higher systematic review TCID50 tissue transmission route Ventilation viability viral culture Viral load virus viruses Web of Science [DOI] 10.1001/jamanetworkopen.2020.33232 PMC 바로가기 [Article Type] Research
Analyzing the dominant SARS-CoV-2 transmission routes toward an ab initio disease spread modelARTICLES Published on 2020-12-012022-10-28 Journal: Physics of Fluids [Category] COVID-19, [키워드] analyzed average basic reproduction number calculate calculated caused Combination Combined Contact cough determine Dilution disease spread dominant droplet droplets encapsulate Evolution Frequency highest identifying Infection infection rate infectious dose Inhaled initial molecular nuclei pandemic physical Probability reduce Research SARS-CoV-2 transmission sensitivity shown susceptible the SARS-CoV-2 virus Transmission transmission route Variation Viral load virion virus while [DOI] 10.1063/5.0034032 PMC 바로가기 [Article Type] ARTICLES
Risk for Hepatitis E Virus Transmission by Solvent/Detergent–Treated PlasmaArticle Published on 2020-12-012023-06-09 Journal: Emerging Infectious Diseases [Category] E형 간염, Fulltext, [키워드] Blood donors France hepatitis E virus HEV infectious dose plasma Retrospective study solvent/detergent–treated plasma Transmission viruses zoonoses [DOI] 10.3201/eid2612.191482 PMC 바로가기
Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020Research Published on 2020-04-232022-10-31 Journal: Eurosurveillance [Category] COVID-19, SARS, [키워드] acute respiratory syndrome antibody approach Assessing attack rate carried Combination controls coronavirus coronavirus disease COVD19 COVID-19 Critical cross-reactivity Culture detect detectable develop disease severity dose ELISA evaluate evaluated health systems healthy controls IgG and IgM IgG ELISA illness onset Immunity Impact Infection infectious dose Interpretation neutralisation test neutralization pandemic Patient plasma positive PRNT public health Public health interventions RBD RBD ELISA real time Receptor binding domain reduce reduction Result SARS-CoV-2 SARS-CoV-2 antibody Sensitivity and specificity sera Serological assay serology shown the RBD the receptor-binding domain the spike protein tissue virus [DOI] 10.2807/1560-7917.ES.2020.25.16.2000421 PMC 바로가기 [Article Type] Research
Quantitative Proteomic Analysis Reveals Antiviral and Anti-inflammatory Effects of Puerarin in Piglets Infected With Porcine Epidemic Diarrhea VirusImmunology Published on 2020-02-262022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, MERS, [키워드] activities addition Administered African green monkey analyses Analysis Anti-inflammatory anti-inflammatory effect Anti-viral Antiviral assigned Blood caused Cell cell proliferation Chinese collected conducted Control control group control level Culture cytokine determine Effect effective epidemic diarrhea expression group growth IL-8 in vitro in vivo Infection infectious dose inhibited interferon-stimulated gene intestinal kidney mechanism multiplicity of infection Neonatal NF-κB activation PEDV pharmacological Piglets Porcine epidemic diarrhea virus Protein Proteins proteomic proteomics puerarin Randomly reductions in Replication restored serum-free DMEM sterile saline TCID three group tissue treated Trial two group upregulated Vero Vero Cell virus Volume were infected Western blot analysis [DOI] 10.3389/fimmu.2020.00169 PMC 바로가기 [Article Type] Immunology