initial symptoms – Page 4 – Communicable Diseases Research

One-Seventh of Patients with COVID-19 Had Olfactory and Gustatory Abnormalities as Their Initial Symptoms: A Systematic Review and Meta-Analysis

Article

Published on 2020-08-222022-10-29
Journal: International Review of Cell and Molecular Biology [Category] COVID-19,

Quantitative lung lesion features and temporal changes on chest CT in patients with common and severe SARS-CoV-2 pneumonia

Research Article

Published on 2020-07-242022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

Pathological Aspects of COVID-19 as a Conformational Disease and the Use of Pharmacological Chaperones as a Potential Therapeutic Strategy

Pharmacology

Published on 2020-07-102022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] acute respiratory syndrome adaptive addition Administered alveolar epithelial cells antiviral therapy Apoptosis artificial ventilation aspect BiP cardiac troponin cell death cell types cellular damage cellular response chaperone conformational coronavirus Coronavirus disease 2019 Coronavirus-2 cough COVID-19 COVID-19 patient creatinine D-dimer damaged deaths dialysis disorder dysfunction Efficacy Endoplasmic reticulum ER stress excessive immune response fatigue Fever glucocorticoid host cell IL-6 increase increase in induce Infection Infectious disease Inflammation initial symptoms interleukin-6 Johns Hopkins University liver enzymes Lymphocytes mechanism membrane multiple organ failure myalgia neuronal cells occur occurred organ support Oxygen therapy Oxygenation pathological pharmacological pharmacological chaperone Pneumonia Potential progressed Protein Proteostasis renal tubular cells Replication reported required SARS-CoV-2 serum severe cases severely ill patients Spread sputum production Strategy survival rate the disease therapy treat unfolded protein response unfolded protein response (UPR) vascular endothelial cells viral infection viral proliferation Wuhan, China
[DOI] 10.3389/fphar.2020.01095 PMC 바로가기 [Article Type] Pharmacology

Clinical characteristics of 82 cases of death from COVID-19

코로나19 사망자 82명의 임상적 특징

Research Article

Published on 2020-07-092022-08-13
Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS,

[키워드] Admission age Alanine alanine aminotransferase aspartate Aspartate aminotransferase association C-reactive protein Cancer cardiac failure cause of death caused Cerebrovascular disease Characteristics clinical Clinical characteristics Clinical data Comorbidities Comorbidity COVID-19 cytokine cytokine release Cytokine release syndrome D-dimer Data collection death death case detected patients develop diabete diabetes diagnosed died disease electronic medical record followed by forms heart disease hemorrhage Hemorrhagic hemorrhagic damage hypertension ICU IL-6 initial symptom initial symptoms IQR laboratory-confirmed Lactate lactate dehydrogenase Local lymphocyte lymphopenia male mechanical ventilation support median age median time medical records MOST Most patient Most patients neutrophil Neutrophil-to-lymphocyte ratio neutrophilia Older on admission other organs oxygen Patient patients Pneumonia proportion remained renal renal damage renal failure respiratory Respiratory failure SARS-CoV-2 SARS-COV-2 infection Sepsis severe disease single center Spread systemic immune-inflammation index the median the patient thrombocytopenia treated virus Wuhan Wuhan local hospital’ Wuhan, China
[DOI] 10.1371/journal.pone.0235458 PMC 바로가기 [Article Type] Research Article

Analysis of clinical features and early warning signs in patients with severe COVID-19: A retrospective cohort study

Research Article

Published on 2020-06-262022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

[키워드] 95% CI absolute lymphocyte Analysis assigned C-reactive protein characteristic China clinical feature collected Coronavirus disease 2019 COVID-19 COVID-19 patients demographic described determine died discharged effective intervention electronic medical record enrolled extracorporeal membrane oxygenation groups High-flow oxygen higher risk hospital identify implementation indicated information initial symptoms Invasive mechanical ventilation less Logistic Logistic regression analysis morbidity multivariate non-severe group noninvasive Odds ratio Patient predictor previous study renal replacement therapy retrospective cohort study risk severe COVID-19 threshold Treatment was performed was used Wuhan, China
[DOI] 10.1371/journal.pone.0235459 PMC 바로가기 [Article Type] Research Article

Clinical and epidemiological characteristics of pediatric SARS-CoV-2 infections in China: A multicenter case series

Research Article

Published on 2020-06-162022-10-29
Journal: PLoS Medicine [Category] COVID-19, SARS,

[키워드] acute respiratory syndrome addition Admission Adults All the patient Analysis analyzed case sery Characteristics chest computed tomographic children China clinical Clinical data clinical feature clinical presentation Cluster collected Computed tomography coronavirus cough Course COVID-19 death decrease demographic data described diagnosed diarrhea discharged duration of hospitalization early diagnosis effective Epidemic epidemiological Evidence expectoration feature Features Fever Final Follow-up form ground-glass opacity High-sensitivity C-reactive protein hospital Infection inflammatory markers information initial symptom initial symptoms interquartile range Intervention Laboratory tests lack lactate dehydrogenase lesion lesions male median Mild mixed infection moderate multicenter offer outcomes Patient patients patients with COVID-19 pediatric pediatric cases Pediatric patient performed physician progression proportion radiologic radiological Rapid reported researcher respiratory pathogen retrospective risk SARS-CoV-2 SARS-COV-2 infection serum amyloid significant increases in small sample size Spread Symptom Symptoms systemically the disease the epidemic the median the patient Transmission Treatment virus vomiting was performed West with COVID-19 α-Hydroxybutyrate dehydrogenase
[DOI] 10.1371/journal.pmed.1003130 PMC 바로가기 [Article Type] Research Article

COVID-19 and ECMO: the interplay between coagulation and inflammation—a narrative review

Review

Published on 2020-05-082022-11-01
Journal: Critical Care [Category] COVID-19, MERS, SARS,