Humoral immunological kinetics of severe acute respiratory syndrome coronavirus 2 infection and diagnostic performance of serological assays for coronavirus disease 2019: an analysis of global reports중증 급성 호흡기 증후군 코로나바이러스 2 감염의 체액 면역 역학 및 코로나바이러스 질병 2019에 대한 혈청학적 분석의 진단 성능: 글로벌 보고서 분석Review Published on 2022-01-192022-09-11 Journal: International health [Category] SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgM applicability article Blood Characteristics chemiluminescence immunoassay CLIA coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 serology diagnosis of COVID-19 diagnostic diagnostics eligible ELISA epidemiological purposes followed by humoral immune response IgG IgM immunological IMPROVE in some Infection Kinetics Laboratory laboratory diagnosis Laboratory tests lateral flow medical subject heading Medical Subject Headings medRxiv MONITOR pandemic peaked performance POCT point-of-care Postinfection protocol provide reported Research SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 test searched second wave serological Serological assay serological assays serological test serology severe acute respiratory syndrome Coronavirus thresholds total antibodies total antibody was performed Web of Science [DOI] 10.1093/inthealth/ihab005 PMC 바로가기 [Article Type] Review
Development and external validation of prognostic models for COVID-19 to support risk stratification in secondary careInfectious Diseases Published on 2022-01-172022-10-28 Journal: BMJ Open [Category] Coronavirus, Fulltext, SARS, [키워드] 95% CI Admission adverse outcome Area AUROC calculate candidate characteristic clinical utility collected Comorbidities Comorbidity COVID-19 dataset datasets death Demographic variables develop development died electronic medical record evaluated External external validation hospital Hospital admission IMPROVE information Intensive Laboratory tests lack Logistic regression Measures Model Mortality objective outcome measure participant Patient patients with COVID-19 performed physiological predictor predictors Probability prognostic model public health respiratory Result risk stratification secondary care setting Support Symptoms therapy university was performed with COVID-19 [DOI] 10.1136/bmjopen-2021-049506 PMC 바로가기 [Article Type] Infectious Diseases
Machine learning for emerging infectious disease field responsesArticle Published on 2022-01-102022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] age and gender analysed approach biomedical engineering Comorbidity COVID-19 pandemic demonstrated develop Disease progression Effect effective Emerging infectious disease global public health Health services healthcare healthcare facility Hospital admission identify imperative Infectious disease Infectious diseases Laboratory tests machine medical resource minor symptom mortality risk occurred outbreak Patient patients physician protective immunity public health raised response risk Risk factors Spread Vaccination strategy [DOI] 10.1038/s41598-021-03687-w PMC 바로가기 [Article Type] Article
OpenSAFELY NHS Service Restoration Observatory 1: primary care clinical activity in England during the first wave of COVID-19Research Published on 2022-01-092022-10-28 Journal: The British Journal of General Practice [Category] COVID-19, SARS, [키워드] activity affected baseline chronic obstructive clinical clinical activity coded cohort study conducted COVD-19 COVID-19 COVID-19 pandemic declined described Electronic health records England exhibited expected First wave General practice healthcare Infection International Laboratory Laboratory test Laboratory tests less median MOST NHS Observatory OpenSAFELY pandemic Patient primary care Primary Health Care pulmonary disease recorded reduction remained respiratory Respiratory disease respiratory symptom restoration restored Result service sustained term Variation Version Volume working [DOI] 10.3399/BJGP.2021.0380 PMC 바로가기 [Article Type] Research
Circulating levels of calprotectin, a signature of neutrophil activation in prediction of severe respiratory failure in COVID-19 patients: a multicenter, prospective study (CalCov study)Observational Study Published on 2022-01-012022-10-05 Journal: Inflammation research : official journal of the Eu [Category] 임상, [키워드] Accuracy Activation Admission admitted to ICU adult COVID-19 patients Analysis blood sample calprotectin can be used characterized collected COVID-19 COVID-19 patients Critical dysregulated immune response evaluate ICU ICU admission ICU patient independent intensive care unit Intubated Invasive mechanical ventilation involved Laboratory tests multicenter neutrophil neutrophil activation Neutrophil activation. patients predict Primary outcome prospective observational study Prospective Study reflect required ROC AUC secondary outcome serum severe COVID-19 severe respiratory failure severity significantly higher [DOI] 10.1007/s00011-021-01516-4 PMC 바로가기 [Article Type] Observational Study
The impact of COVID-19 on Diabetic Ketoacidosis patientsResearch article Published on 2022-01-012022-10-05 Journal: Diabetes & metabolic syndrome [Category] 바이오마커, [키워드] Admission anion Blood Cohort coronavirus disease 19 COVID-19 COVID-19 severity Critical care Definition demographics diabetes diabetic ketoacidosis DKA emergency medicine excluded Gap greater had more hospital Hospitalization ICU Infectious disease Intervention ketoacidosis Laboratory tests Mortality mortality rate New York City outcome oxygen saturation pandemic participant past medical history Patient PCR testing Prevalence renal Result secondary outcome selected transfer vital signs [DOI] 10.1016/j.dsx.2022.102389 [Article Type] Research article
SARS-CoV-2 Post Vaccinated Adverse Effects and Efficacy in the Egyptian PopulationArticle Published on 2021-12-242022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] administration Adverse adverse effects Anti-spike antibody Antibody titers average collected COVID-19 detect determine dose doses Effect fatigue headache IgG Immunity IMPROVE injection Laboratory tests lethargy Mild MOST much higher no symptom overcome participant Participants Population positive Post-vaccine questionnaire required SARS-CoV-2 SARS-COV-2 infection second dose Sinopharm Sinopharm vaccine Spike protein Symptom vaccination Vaccine [DOI] 10.3390/vaccines10010018 PMC 바로가기 [Article Type] Article
From asymptomatic to critical illness: decoding various clinical stages of COVID-19Article Published on 2021-12-172022-10-29 Journal: Turkish Journal of Medical Sciences [Category] COVID-19, SARS, [키워드] accompanied Acute heart failure Acute liver injury acute renal failure affected age ARDS Arrhythmias Asymptomatic average Bacterial C-reactive protein changes in Chest Chronic diseases Clinical course Clinical features clinical monitoring Clinical stage Coagulopathy Comorbidities Complication complications cough Course COVID-19 Critical D-dimer develop diarrhea disease disease severity disorders element Fatality rate ferritin Fever Fungal infection groups headache Hospitalized hospitalized patient immunosuppressants Immunosuppressed incidence include Insomnia intensive care Laboratory tests lung damage lymphopenia malaise Mild myalgia myocarditis Neuropsychiatric pathological change Patient patients Pneumonia poor prognosis Prognosis prothrombotic reported resulting risk risk factor Risk factors secondary Sepsis Septic shock Shortness of breath shown sore throat steroid Symptom Symptoms the patient therapy Thromboembolic events undergo venous [DOI] 10.3906/sag-2107-137 PMC 바로가기 [Article Type] Article
Harmony COVID-19: A ready-to-use kit, low-cost detector, and smartphone app for point-of-care SARS-CoV-2 RNA detectionResearch Article Published on 2021-12-152022-10-28 Journal: Science Advances [Category] COVID-19, [키워드] Accuracy acute respiratory syndrome amplification Analysis coronavirus coronavirus disease COVID-19 description detect faster harmony Health care worker health worker Infection isothermal amplification Laboratory tests nasal performed point-of-care positive reagents Respiratory pathogens reverse transcription RNA RT-LAMP Saliva SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RNA detection specificity specimen unique Usability [DOI] 10.1126/sciadv.abj1281 PMC 바로가기 [Article Type] Research Article
Pediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 symptoms in IranCase Series Published on 2021-11-262022-10-31 Journal: Future Virology [Category] COVID-19, [키워드] antivirals Combination complications COVID-19 diagnosed discharged Fever healthy hospital Hospitalization immune Inflammatory intravenous Iran irritability IVIG Laboratory tests material pediatric Pediatric patient physician PIMS-TS raised refusal SARS-CoV-2 screened Symptom syndrome the patient treated Treatment [DOI] 10.2217/fvl-2021-0156 PMC 바로가기 [Article Type] Case Series