log-rank test – Page 4 – Communicable Diseases Research

Continuous positive airway pressure for respiratory support during COVID-19 pandemic: a frugal approach from bench to bedside

Research

Published on 2021-03-022022-10-28
Journal: Annals of Intensive Care [Category] COVID-19,

Effectiveness of mid-regional pro-adrenomedullin (MR-proADM) as prognostic marker in COVID-19 critically ill patients: An observational prospective study

COVID-19 중환자에서 예후 마커로서 중부 프로아드레노메둘린(MR-proADM)의 효과: 관찰 전향 연구

Observational Study

Published on 2021-02-082022-08-13
Journal: PLoS ONE [Category] Biochemistry, MERS, 바이오마커, 임상,

[키워드] 48 hour 48 hours 95% confidence interval adjusted Admission age AUC best Biomarkers C-reactive protein cardiovascular disease characterized COVID-19 COVID-19 adult patient COVID-19 ICU-patients COVID-19 patients COVID-19-ICU-patients Critically ill CRP CRP level CRP levels cut-off D-dimer diabetes Diabetes Mellitus dying patient dying patients effective Effectiveness enrolled explain Gender group higher mortality characterized patients ICU ICU admission increase in Laboratory Laboratory test Lactate lactate dehydrogenase LDH log-rank test logistic regression model lymphocyte Lymphocytes lymphocytopenia mechanism mid-regional pro-adrenomedullin Mortality MR-proADM MR-proADM measurement non-survivor NT-pro-BNP objective Odds ratio overall mortality Patient patients PCT predict Predictive procalcitonin Prognostic marker Prospective Study receiver-operating characteristics curves Referral responsible Result significantly Support survival curve Survival curves surviving and non-surviving patients tested university hospital were measured
[DOI] 10.1371/journal.pone.0246771 PMC 바로가기 [Article Type] Observational Study

Decreased CO 2 Levels as Indicators of Possible Mechanical Ventilation-Induced Hyperventilation in COVID-19 Patients: A Retrospective Analysis

COVID-19 환자의 기계적 환기로 인한 과호흡 가능성의 지표로서의 CO 2 수준 감소: 후향적 분석

Public Health

Published on 2021-01-082022-09-11
Journal: Frontiers in Public Health [Category] MERS, 바이오마커,

[키워드] 95% CI adjusted hazard ratio adjusted hazard ratios adjusted odds ratio Analysis caused clinical experience Clinical treatment CO₂ collected Computed tomography conducted confidence interval coronavirus coronavirus disease correlated correlation COVID-19 COVID-19 patient COVID-19 patients COVID-19 progression Cox regression Cox regression analysis Curve Decreased demonstrated determine disease severity higher risk hyperventilation Indicator Infectious disease information Kaplan-Meier curve Kaplan-Meier survival curve Kaplan-Meier survival curves Level log-rank test Mechanical mechanical ventilation medical record medical records Mortality mortality risk outbreak pandemic Patient Pneumonia Prognosis provide recommendations Survival curves the log-rank test the patient was used Wuhan
[DOI] 10.3389/fpubh.2020.596168 PMC 바로가기 [Article Type] Public Health

Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia

코로나19 폐렴으로 입원한 환자의 토실리주맙

Randomized Controlled Trial

Published on 2021-01-072022-09-11
Journal: The New England Journal of Medicine [Category] Fulltext, MERS, 임상, 진단,

[키워드] 95% CI 95% confidence interval Alaska antibody assigned black body weight clinical coronavirus disease Coronavirus disease 2019 COVID-19 pneumonia cumulative death died dose Efficacy EMPACTA ethnic group Genentech hazard ratio Hispanic Hospitalized hospitalized patient hospitalized patients hyperinflammation IMPROVE incidence Inclusion intravenously kilogram Latino likelihood log-rank test mechanical ventilation modified intention-to-treat Native occurred outcome Patient patients hospitalized Placebo placebo group Pneumonia Population populations Primary outcome progression Racial randomization Randomly receive receiving receptor reduced safety population Serious Adverse Event Serious Adverse Events Site standard care survival the log-rank test the patient the placebo group time-to-event analysis Tocilizumab treat white
[DOI] 10.1056/NEJMoa2030340 PMC 바로가기 [Article Type] Randomized Controlled Trial

Clinical implication and risk factor of pneumonia development in mild coronavirus disease 2019 patients

Observational Study

Published on 2021-01-012022-10-05
Journal: The Korean journal of internal medicine [Category] SARS, 임상,

Intravenous methylprednisolone pulse as a treatment for hospitalised severe COVID-19 patients: results from a randomised controlled clinical trial

입원한 중증 COVID-19 환자를 위한 치료제로서의 정맥내 메틸프레드니솔론 펄스: 무작위 대조 임상 시험의 결과

Randomized Controlled Trial

Published on 2020-12-242022-08-13
Journal: The European Respiratory Journal [Category] 임상,

[키워드] 1:1 95% CI administration Analysis attending physician Block randomisation Clinical improvement clinical trial conducted Controlled clinical trial Corticosteroid Corticosteroids COVID-19 COVID-19 patient COVID-19 patients death demonstrated eligible patient hazard ratio hospitalised hospitalised patient Immunosuppressive treatment Inflammation Inflammatory marker inflammatory markers initiation of treatment intention-to-treat Intravenous injection Iran ITT log-rank test Methylprednisolone methylprednisolone group mortality rate oxygen oxygen saturation Patient pulmonary involvement pulse randomisation randomised controlled Randomly receive reduce respiratory Respiratory system Result safety analysis severe adverse event severe adverse events severe COVID-19 severe COVID-19 patient significantly increased significantly lower single-blind standard care standard care group suggested survival survival time therapeutic therapeutic agent Treatment Two patient two patients was done were excluded
[DOI] 10.1183/13993003.02808-2020 PMC 바로가기 [Article Type] Randomized Controlled Trial

Efficacy of Traditional Chinese Medicine, Maxingshigan-Weijing in the management of COVID-19 patients with severe acute respiratory syndrome: A structured summary of a study protocol for a randomized controlled trial

중증 급성 호흡기 증후군이 있는 COVID-19 환자 관리에 대한 중국 전통 의학 Maxingshigan-Weijing의 효능: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2020-12-232022-08-31
Journal: Trials [Category] MERS, SARS, 임상, 치료제,

[키워드] 1:1 acute respiratory syndrome acute respiratory syndrome coronavirus addition administration Affiliated Hospital age allergic allergies anorexia anti-bacterial Anti-viral anticipated Anxiety Arm asked Asymptomatic automatically aversion blinded Blinding Blood tinged blood tinged sputum both groups Care carried center checklist Chenpi chest pain chest X-ray Chinese Chinese Clinical Trial Registry Chinese herbal medicines clinical clinical symptom clinical trials clinically Cold comparator Patients composed control group Controlled trial coronavirus cough COVID-19 COVID-19 patient criteria critical patient critical patients defined diarrhea disease Diseases dissemination distension Dizziness dry mouth dysphoria effective Efficacy element Eligible patients ephedra exclusion criteria expectoration female Fever Follow-up four-point scale Gypsum H1N1 H1N1 influenza headache hematopoietic system Herba Ephedra herbal medicine hospital IBM IBM Corp IMPROVE improvement in both group include Inclusion inclusion and exclusion criteria inclusion criteria individual Influenza Informed consent Inpatient Insomnia Kaplan-Meier method kidney Kidney function lactation less liver log-rank test malaise male management Maxingshigan-weijing mechanical ventilation Medicine Melon Mild mild clinical symptoms multicenter multiple organ failure muscular nasal nasal obstruction nausea nausea and vomiting negative test nucleic acid number objective open Open-label oral administration outcome participant Patient patients Peach pharyngalgia Pneumonia positive Pregnancy previous study Primary outcome Professor proportion protocol Radix random random allocation random number generator randomisation randomised Randomized Randomized controlled trial randomly divided receive recruited registry reported researcher respiratory Respiratory failure respiratory symptom Sample size SARS-CoV-2 SARS-CoV-2 nucleic acid Scoring second secondary Secondary outcomes Semen sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity Shock Shortness of breath statistical analysis Statistical power Statistics status Study protocol suffering supplementary material supportive care survival survival time sweating Symptom symptomatic Symptoms System TCM temperature test results the median therapy total score Traditional Traditional Chinese medicine treated Treatment trial protocol Trial registration Trichosanthe Trichosanthes Kirilowii university USA Version virus pneumonia vomiting website wheezing Winter Withdrawal
[DOI] 10.1186/s13063-020-04970-3 PMC 바로가기 [Article Type] Letter

Identification and Validation of a Novel Clinical Signature to Predict the Prognosis in Confirmed Coronavirus Disease 2019 Patients

Randomized Controlled Trial

Published on 2020-12-152022-10-05
Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 임상,

[키워드] Accuracy age Analysis both group C-reactive protein caused characteristic clinical Confirmed coronavirus coronavirus disease COVID-19 COVID-19 patient Critically ill demonstrated disease group groups highest identification identify indicated log-rank test Lymphocyte count mortality rate multivariate Cox regression neutrophil count novel Patient performed predict prediction Predictive Probability procalcitonin Prognosis prognostic biomarker randomly divided reduce risk risk model ROC ROC analysis signature significantly stratified surpassed survival the disease Treatment validation was selected worldwide pandemic
[DOI] 10.1093/cid/ciaa793 PMC 바로가기 [Article Type] Randomized Controlled Trial

Low 25-Hydroxyvitamin D Levels on Admission to the Intensive Care Unit May Predispose COVID-19 Pneumonia Patients to a Higher 28-Day Mortality Risk: A Pilot Study on a Greek ICU Cohort

Brief Report

Published on 2020-12-092022-10-04
Journal: Nutrients [Category] MERS, SARS, 임상,

Prognostic Significance of COVID-19 Receptor ACE2 and Recommendation for Antihypertensive Drug in Renal Cell Carcinoma

Research Article

Published on 2020-11-252022-10-27
Journal: BioMed Research International [Category] COVID-19, MERS,

[키워드] ACE ACE2 ACE2 expression acute respiratory syndrome anti-hypertensive drug antihypertensive antihypertensive agent atlas Cell cell membrane coronavirus coronavirus disease COVID-19 Cox proportional hazard Cox regression downloaded drug enzyme Epidemic genomic data glioblastoma multiforme increase inhibitor Kaplan-Meier Kaplan-Meier curve kidney log-rank test Lungs material Melanoma molecular docking offer pandemic patients Prognosis prognostic Prostate renal renal cell carcinoma Research Result Significance Spread statistical significance surface protein survival rate Thyroid uveal World Health Organization
[DOI] 10.1155/2020/2054376 PMC 바로가기 [Article Type] Research Article