USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STINGUSP22는 STING의 활성화를 통해 III형 인터페론 신호 전달 및 SARS-CoV-2 감염을 제어합니다Article Published on 2022-08-062022-09-11 Journal: Cell Death & Disease [Category] SARS, 유전자 메커니즘, 치료제, [키워드] absence Activation Antiviral basal causative agent Control COVID-19 pandemic de novo Defense enzyme epithelial cells exogenous IFN expression function Host identify IFN IFN signaling IFN-stimulated gene IFN-stimulated genes IFN-λ IFNs implication interferons interferons (IFNs interferons (IFNs) intestinal epithelial cell involved ISG ISGs long-lasting Particles pattern Pattern recognition Pattern recognition receptors PRRs receptor reversed SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections secretion Signaling STAT Stat1 STING tumorigenesis Type Type III IFN Type III IFNs type III interferon USP22 viral infection viral replication [DOI] 10.1038/s41419-022-05124-w PMC 바로가기 [Article Type] Article
Olfactory impairment in psychiatric disorders: Does nasal inflammation impact disease psychophysiology?정신 장애의 후각 장애: 비염이 질병 정신 생리학에 영향을 줍니까?Review Published on 2022-08-052022-09-11 Journal: Translational Psychiatry [Category] 유전자 메커니즘, [키워드] adverse effect Brain brain development cause Clinical studies clinical study contribute coronavirus disease Coronavirus disease 2019 COVID-19 Critical Depression disease environmental factor environmental factors Evidence followed by functions illness impairment Inflammation involved long-lasting Mental nasal Neuropsychiatric olfactory olfactory dysfunction olfactory function outbreak outcome pathophysiological mechanism pathophysiological mechanisms pathophysiology produced Psychiatric Psychiatric disorders Psychopathology recent Regulation Research respiratory viral infection respiratory viral infections risk Schizophrenia [DOI] 10.1038/s41398-022-02081-y PMC 바로가기 [Article Type] Review
Nasopharyngeal microbiota profiling of pregnant women with SARS-CoV-2 infectionSARS-CoV-2 감염 임산부의 비인두 미생물총 프로파일링Multicenter Study Published on 2022-08-042022-09-12 Journal: Scientific Reports [Category] SARS, 진단, [키워드] 16S rRNA acute infection Alpha amplified antibodies antibody association ASV Bacteria Bacteroidete Barcelona change COVID-19 pandemic cross-sectional diagnosed DNA enrolled evaluated Infection long-lasting microbiota Mild multicenter nasopharyngeal Nasopharyngeal swab negative RT-PCR Peripheral blood population-based cohort positive positive RT-PCR Pregnancy pregnant women Primers profile Randomly reported RT-PCR SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 IgG SARS-COV-2 infection selected severe cases significant difference Spain Tenericute was determined was tested women [DOI] 10.1038/s41598-022-17542-z PMC 바로가기 [Article Type] Multicenter Study
Nanoparticles in clinical trials of COVID-19: An updateReview article Published on 2022-08-012022-10-05 Journal: International journal of surgery (London, England) [Category] 변종, 임상, 치료제, [키워드] approved benefit Bioavailability clinical trial clinical trials COVID-19 COVID-19 disease COVID-19 vaccination drug delivery drugs effective effective vaccine Efficacy Efficiency effort example exhibit globe highlighting Immunity Immunotherapy inaccessible increasingly indication Infectious disease investigated long-lasting medication Medicine Medicines nanoparticle Nanoparticles outbreak outcomes pandemic provide reducing researcher Safe SARS-CoV-2 antigen Strategy therapeutic therapy Toxicity Treatment Vaccine Vaccines WHO World Health Organization [DOI] 10.1016/j.ijsu.2022.106818 [Article Type] Review article
Fatigue In Covid-19 Survivors: The Potential Impact Of A Nutritional Supplement On Muscle Strength And FunctionResearch article Published on 2022-08-012022-10-05 Journal: Clinical nutrition ESPEN [Category] 바이오마커, [키워드] acute COVID-19 affected aging All participant amino acids Analysis analyzed blood biochemistry Body body composition Chair stand test COVID-19 enrolled evaluate evaluated fatigue ferritin level ferritin levels function hand hand grip strength Health Health status Hospitalized Impact invasive ventilation laboratory parameter Long COVID long-lasting low-flow oxygen supplementation Minerals muscle Muscle function Muscle strength NIV Noninvasive ventilation not significant Older parameters participant Patient performed physical Potential Quality of life reduced reduction repetition Result Rome strength strength test survivor Survivors Tolerance Visual Analogue Scale vitamins was obtained [DOI] 10.1016/j.clnesp.2022.08.029 [Article Type] Research article
Impact of the SARS-CoV-2 pandemic on trauma care: a nationwide observational studyObservational Study Published on 2022-08-012022-10-04 Journal: European Journal of Trauma and Emergency Surgery [Category] COVID19(2023년), SARS, 임상, [키워드] addition Admission aetiology Care changes Effect epidemiological Epidemiology Health hospital ICU Impact incidence increase in Injury INT ISS long-lasting median multicentre negatively affected Netherlands Observational cohort study outcome pandemic Prevalence registry resource resources SARS-CoV-2 SARS-CoV-2 pandemic second wave significantly significantly higher the SARS-CoV-2 trauma trauma patient treated was performed was recorded was reduced [DOI] 10.1007/s00068-022-01891-5 PMC 바로가기 [Article Type] Observational Study
Effects of vaccination, new SARS-CoV-2 variants and reinfections on post-COVID-19 complications백신 접종, 신종 SARS-CoV-2 변종 및 재감염이 코로나19 이후 합병증에 미치는 영향Article Published on 2022-07-292022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, [키워드] Care Complication complications connection COVID-19 Effect functional Health Health care Health care system Hypothesis investigated knowledge long-lasting mechanism mechanisms new research directions new SARS-CoV-2 Occurrence Pathogenesis post-COVID-19 complications potential mechanism potential mechanisms Prevalence prevention strategies Probability Reinfection Research responsible risk factor Risk factors SARS-CoV-2 SARS-CoV-2 new variants SARS-CoV-2 reinfections SARS-CoV-2 variants severity survivor Survivors vaccination Vaccination Status variant variety [DOI] 10.3389/fpubh.2022.903568 PMC 바로가기 [Article Type] Article
Transient and durable T cell reactivity after COVID-19COVID-19 이후 일시적이고 지속적인 T 세포 반응성Article Published on 2022-07-262022-09-11 Journal: Proceedings of the National Academy of Sciences of [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analyzed Antigen antigens Cell convalescent patient Convalescent patients coronavirus correlated COVID-19 cytokine Cytokines determine Ex vivo followed by IL-12 IL-13 IL-17 IL-2 Infection interferon interferon-γ interleukin long-lasting Longevity median N-terminal nucleocapsid protein Patient peptide peptides Polarity Protein reactivity remained respiratory retrieved SARS-CoV-2 severe acute respiratory syndrome Coronavirus stimulated synchronous T cell T cell cytokines T cell memory T helper T helper cells Transient triggered whole blood sample [DOI] 10.1073/pnas.2203659119 PMC 바로가기 [Article Type] Article
Brief Research Report: Anti-SARS-CoV-2 Immunity in Long Lasting Responders to Cancer Immunotherapy Through mRNA-Based COVID-19 Vaccination간략한 연구 보고서: mRNA 기반 COVID-19 백신 접종을 통한 암 면역 요법에 대한 오래 지속되는 응답자의 항 SARS-CoV-2 면역Article Published on 2022-07-052022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] analysed antibodies antibody Antibody Response antiviral immune response BNT162b2 Cancer Cancer immunotherapy Cohort Complete Control control group COVID COVID-19 COVID-19 vaccination develop ELISA generate group healthy control IFN-γ IgG titer IgGs immune Immune checkpoint inhibitor immune checkpoint inhibitors (ICIs) immune response Immunotherapy increase in independent induce Long long lasting responders long-lasting median mRNA-based COVID-19 vaccine mRNA-based vaccine mRNA-based vaccines NAb neutralizing antibody neutralizing capacity Patient patients treated prime-boost regimen receiving regimen respond Responder responders responses SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific IgG serum antibodies significantly increased solid tumors statistically significant T cell response T cell responses T cells the healthy the patient treated vaccination Vaccine virus [DOI] 10.3389/fimmu.2022.908108 PMC 바로가기 [Article Type] Article
Prolonged shedding of infectious viruses with haplotype switches of SARS-CoV-2 in an immunocompromised patient면역 저하 환자에서 SARS-CoV-2의 일배체형 스위치로 감염성 바이러스의 장기간 배출Case Reports Published on 2022-07-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] accumulated acquired immunity Bendamustine Clinical course Complete Complete Remission convalescent stage COVID-19 COVID-19 case COVID-19 infection COVID-19 pneumonia detectable eight episode episode of follicular Follicular lymphoma Haplotype Host immune Immunity Immunocompromised Immunocompromised host Immunocompromised patient Infectious virus infectiousness Infectivity initial kinetic long-lasting lymphoma management mechanical ventilation Non-synonymous mutation Patient Pneumonia Prolonged raised required Respiratory failure rituximab SARS-CoV-2 SARS-CoV-2 variants spike gene suppressed tested the SARS-CoV-2 variants Viral Viral kinetic. Viral RNA [DOI] 10.1016/j.jiac.2022.04.004 PMC 바로가기 [Article Type] Case Reports