High-titre convalescent plasma therapy for an immunocompromised patient with systemic lupus erythematosus with protracted SARS-CoV-2 infection장기간의 SARS-CoV-2 감염을 동반한 전신성 홍반성 루푸스가 있는 면역저하 환자를 위한 고역가 회복기 혈장 요법Case Reports Published on 2021-08-252022-09-11 Journal: BMJ case reports [Category] SARS, 치료기술, [키워드] Administered anti-CD20 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody Antimicrobial therapy Biological agents Bronchoalveolar lavage cell cultures Clinical improvement convalescent plasma Convalescent plasma therapy Corticosteroid COVID-19 COVID-19 pneumonia Dexamethasone High-dose hospital hypoxaemia Immunocompromised Immunocompromised patient lung opacities lupus erythematosus monoclonal antibody opportunistic infection opportunistic Infections PCR Pneumonia positive receiving Respiratory system reverse transcription PCR rituximab SARS-CoV-2 SARS-COV-2 infection symptom onset systemic lupus erythematosus Transcription treated Treatment virus replication with COVID-19 [DOI] 10.1136/bcr-2021-244853 PMC 바로가기 [Article Type] Case Reports
Adaptive Immunity and the Risk of Autoreactivity in COVID-19COVID-19의 적응 면역 및 자가반응 위험Review Published on 2021-08-202022-09-12 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 진단, [키워드] adaptive affecting antigens association autoantibodies Autoimmune disease Autoimmune diseases Autoimmunity autoreactivity Complication COVID-19 COVID-19 patients disease exacerbate expressed Immune cell immune cells immune responses immune system Immunity Infection insight lupus erythematosus mechanism molecular mimicry multiple organs multiple sclerosis Occurrence Pathogens Pathologies PROTECT reported respiratory infection respond response responses SARS-CoV-2 SARS-COV-2 infection self-antigens Side effect Side effects SLE systemic lupus erythematosus target the disease viral infections while [DOI] 10.3390/ijms22168965 PMC 바로가기 [Article Type] Review
Liquid Chromatographic Methods for COVID-19 Drugs, Hydroxychloroquine and ChloroquineCOVID-19 약물, 하이드록시클로로퀸 및 클로로퀸에 대한 액체 크로마토그래피 방법Review Published on 2021-08-182022-09-11 Journal: Journal of chromatographic science [Category] SARS, 치료기술, 치료제, [키워드] 4-aminoquinoline Arthritis Autoimmune diseases biologic biological fluid biological fluids Chloroquine clinical trial clinical trials Complete country Course COVID-19 Determination doctor drug epidemiological studies facilitate HCQ Hydroxychloroquine information liquid lupus erythematosus malaria metabolite Patient pharmaceutical preparations Pharmacodynamics pharmacokinetics provide reported Research rheumatoid arthritis Safe supervision systemic lupus erythematosus Treatment treatment regimen [DOI] 10.1093/chromsci/bmaa110 PMC 바로가기 [Article Type] Review
Combining C reactive protein and serum albumin to predict 90-day mortality in systemic lupus erythematosus with serious community-acquired infectionsOriginal research Published on 2021-07-122024-09-04 Journal: Lupus science & medicine [Category] 대상포진, [키워드] Health care Inflammation lupus erythematosus outcome assessment systemic [DOI] 10.1136/lupus-2021-000505 PMC 바로가기 [Article Type] Original research
Long-term open-label continuation study of the safety and efficacy of belimumab for up to 7 years in patients with systemic lupus erythematosus from Japan and South KoreaOriginal research Published on 2021-07-022024-09-04 Journal: RMD open [Category] 대상포진, [키워드] B-lymphocytes biological therapy Cytokines lupus erythematosus systemic [DOI] 10.1136/rmdopen-2021-001629 PMC 바로가기 [Article Type] Original research
Failure of Anticoagulation to Prevent Stroke in Context of Lupus-Associated Anti-Phospholipid Syndrome and Mild COVID-19루푸스 관련 항인지질 증후군 및 경증 COVID-19의 맥락에서 뇌졸중을 예방하기 위한 항응고 요법의 실패Case Reports Published on 2021-07-012022-09-11 Journal: Journal of stroke and cerebrovascular diseases : t [Category] MERS, 바이오마커, 진단, [키워드] Anti-phospholipid anticoagulation Clinical significance Context COVID-19 COVID-19 infection dysfunction Endothelial cell event failure feature female hypercoagulability hypercoagulable Hypercoagulable state Infection Ischemic Stroke lupus erythematosus Mild pathology Patient phospholipid SARS-CoV-2 virus SARS-CoV-2 virus infection stroke subtype syndrome systemic anticoagulation systemic lupus erythematosus the SARS-CoV-2 virus therapeutic anticoagulation thromboembolic Thromboembolic event Thromboembolic events vascular inflammation virus infection with COVID-19 [DOI] 10.1016/j.jstrokecerebrovasdis.2021.105817 PMC 바로가기 [Article Type] Case Reports
False Positive Results in SARS-CoV-2 Serological Tests for Samples From Patients With Chronic Inflammatory Diseases만성 염증 질환 환자의 샘플에 대한 SARS-CoV-2 혈청 검사의 위양성 결과Immunology Published on 2021-05-032022-09-11 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술, [키워드] analyzed antibody Arthritis autoantibodies Autoimmunity chronic chronic inflammatory disease chronic inflammatory diseases collected defined diagnostics ELISA kit evaluate False positive False positivity house IgG Immunity Immunosuppressant immunosuppressants IMPROVE Infection Inflammatory diseases lateral flow lupus erythematosus majority multiple sclerosis multiplex notable pandemic Patient patients peptide Poor positive produced Result Rheumatoid rheumatoid arthritis rheumatoid factor risk Sample SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 pandemic Serological assay serological assays serological test Serological tests SLE specificity systemic lupus erythematosus Test the SARS-CoV-2 treated [DOI] 10.3389/fimmu.2021.666114 PMC 바로가기 [Article Type] Immunology
IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammationIFN-γ 및 TNF-α는 심각한 COVID-19 폐 및 조직 염증이 있는 염증성 질환에서 확장된 CXCL10+ CCL2+ 대식세포 표현형을 유도합니다Research Published on 2021-04-202022-08-13 Journal: Genome Medicine [Category] MERS, SARS, 유전자 메커니즘, [키워드] affected anti-cytokine antiviral interferon approach Arthritis association bronchoalveolar lavage samples CCL2 CCL3 CD ileum Cell cell-type identification cellular phenotype cellular phenotypes Combination COVID-19 Crohn’s disease CXCL10 CXCL9 Cytokines defined disease-affected donor disease-affected donors disparate Donor driving Effect elevated environmental factor environmental factors established therapy exhibited FIVE GBP1 Genes healthy healthy control healthy subject healthy subjects help human blood-derived macrophage human blood-derived macrophages identify IFN-beta IFN-beta (IFN-β IFN-gamma IFN-β IFN-γ IL1B Immune cell immune cell state immune cell states immune state Immunomodulatory therapies inflamed CD ileum inflamed RA synovium inflamed tissue inflamed tissues Inflammatory inflammatory disease Inflammatory diseases inflammatory factors inflammatory macrophage phenotype Integrative analysis interferon response interferons Interstitial lung disease lung Lung disease lupus erythematosus Macrophage Macrophage heterogeneity macrophage phenotype macrophage phenotypes macrophage state Macrophage stimulation macrophages Meta-analysis mixed-effects modeling Patient patients with COVID-19 pro-inflammatory pro-inflammatory cytokine pro-inflammatory cytokines protective effect RA synovium Result rheumatoid arthritis severe COVID-19 severe COVID-19-affected lungs single-cell Single-cell multi-disease tissue integration single-cell profile Single-cell transcriptomics SLE Stat1 stimulated Stimulation Support systemic lupus erythematosus tested These cells tissue tissue inflammation tissues TNF TNF-α transcriptomic profile Treatment UC colon ulcerative colitis understanding [DOI] 10.1186/s13073-021-00881-3 PMC 바로가기 [Article Type] Research
Hydroxychloroquine and COVID-19: can we learn from the use of rituximab in systemic lupus erythematosus?하이드록시클로로퀸과 코로나19: 전신성 홍반성 루푸스에서 리툭시맙을 사용하여 배울 수 있습니까?Commentary Published on 2021-04-152022-09-01 Journal: The Pan African Medical Journal [Category] 진단, [키워드] anti-CD20 antibody Arthritis asymptomatic patient asymptomatic patients B-cell lymphoma CD20 chimeric COVID-19 debate determine disorders dose duration of treatment effective Effectiveness Efficacy Efficacy and safety evaluate HCQ hematological Hydroxychloroquine lupus erythematosus monoclonal multicentre Neuropsychiatric open Patient profile Randomized controlled trials RCT renal rheumatoid arthritis rituximab RTX Safe SAGA shown SLE SSA Standard therapy systemic lupus erythematosus the disease Treatment understanding [DOI] 10.11604/pamj.2021.38.372.29087 PMC 바로가기 [Article Type] Commentary
Hydroxychloroquine in the post-COVID-19 era: will this pandemic upset decades of clinical practice?코로나19 이후 시대의 하이드록시클로로퀸: 이 전염병이 수십 년간의 임상 관행을 뒤엎을 것입니까?Review Published on 2021-04-012022-09-11 Journal: Clinical Rheumatology [Category] 임상, 치료제, [키워드] Autoimmune disease benefit caused Community Confusion Coverage COVID-19 COVID-19 pandemic COVID-19 pneumonia debate early stage Efficacy Efficacy and safety HCQ Health authority hospitalized patient hospitalized patients Hydroxychloroquine internal medicine lupus erythematosus moderate moderate to severe pandemic Patient risk severe disease Side effects systemic systemic lupus erythematosus Toxicity Treatment [DOI] 10.1007/s10067-020-05572-9 PMC 바로가기 [Article Type] Review