Safety and preliminary efficacy of sequential multiple ascending doses of solnatide to treat pulmonary permeability edema in patients with moderate to severe ARDS in a randomized, placebo-controlled, double-blind trial: preliminary evaluation of safety and feasibility in light of the COVID-19 pandemicRandomized Controlled Trial Published on 2022-04-042022-10-05 Journal: Trials [Category] COVID19(2023년), SARS, 임상, [키워드] activity Alter ARDS ARDS patient Ascending baseline causes Clinical characteristics clinical study clinical trial conducted COVID-19 COVID-19 ARDS patient COVID-19 pandemic COVID-19 patient doses double-blind DSMB edema Efficacy enrolled Enrollment Evidence exceptional feasibility groups indication interim analysis investigator less mandatory Multiple multiple ascending dose noradrenaline not differ observation period outcome Oxygenation pandemic parameter Patient patients with moderate permeability phase IIB placebo-controlled pulmonary Pulmonary edema pulmonary permeability Randomized required risk Safety Safety Monitoring Board SARS-CoV-2 Sepsis severe ARDS sick Solnatide Study design survival rate treat Trial Ventilation [DOI] 10.1186/s13063-022-06182-3 PMC 바로가기 [Article Type] Randomized Controlled Trial
Natriuretic peptide level at heart failure diagnosis and risk of hospitalisation and death in England 2004-20182004-2018년 영국에서 심부전 진단 시 나트륨 이뇨 펩티드 수준 및 입원 및 사망 위험Article Published on 2022-04-012022-09-11 Journal: Heart (British Cardiac Society) [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] 95% CI age all-cause mortality rates association baseline clinical cohort study competing COVID-19 death diagnosed Diagnosis diagnostic England greater guideline Healthcare system Healthcare systems heart heart failure hospitalisation hospitalised IMPROVE IQR mandatory median time men moderate Mortality mortality rate mortality rates Natriuretic NT-proBNP participant Patient peptide Practice pressure Prevent primary care Referral Research risk secondary care survival Treatment while [DOI] 10.1136/heartjnl-2021-319196 PMC 바로가기 [Article Type] Article
Use of Airway Pressure Release Ventilation in Patients With Acute Respiratory Failure Due to COVID-19: Results of a Single-Center Randomized Controlled TrialRandomized Controlled Trial Published on 2022-04-012022-10-05 Journal: Critical Care Medicine [Category] 임상, [키워드] 48 hour acute respiratory distress Airway Pressure Care characterized clinical evidence Controlled coronavirus disease defined Diagnosis expiratory failure greater group groups ICU intubated patient intubation less management mandatory mean difference measurement Mortality no difference outcome Patient pressure Randomized Randomized controlled trial receive recent Release respiratory Result severe coronavirus disease static compliance syndrome Ventilation ventilator-free day ventilatory Volume [DOI] 10.1097/CCM.0000000000005312 PMC 바로가기 [Article Type] Randomized Controlled Trial
SARS-CoV-2 Omicron Variant: Exploring Healthcare Workers’ Awareness and Perception of Vaccine Effectiveness: A National Survey During the First Week of WHO Variant AlertSARS-CoV-2 오미크론 변종: 백신 효과에 대한 의료 종사자의 인식 및 인식 탐색: WHO 변종 경보 첫 주 동안의 전국 설문조사Article Published on 2022-03-252022-09-11 Journal: Frontiers in Public Health [Category] SARS, 변종, [키워드] Adults Awareness booster booster dose COVID-19 COVID-19 vaccine effective Effectiveness eligible female HCW HCWs healthcare worker Healthcare workers healthcare workers' perceptions. Infection prevention mandatory measure Nurses Older omicron Omicron variant other variants Participants Perception Physicians populations Prevent questionnaire receive SARS-CoV-2 SARS-CoV-2 Omicron variant SARS-CoV-2 variant SARS-CoV-2 variants Saudi Arabia significantly social distancing Spread survey tertiary care hospitals the SARS-CoV-2 the vaccine Travel vaccination Vaccine variant variants Week WHO worker [DOI] 10.3389/fpubh.2022.878159 PMC 바로가기 [Article Type] Article
Factors influencing healthcare professionals’ confidence in vaccination in Europe: a literature reviewAcceptance Published on 2022-03-152024-09-04 Journal: Human vaccines & immunotherapeutics [Category] 대상포진, [키워드] beliefs Benefits confidence Effectiveness health-care professionals mandatory Risks Safety Trust Vaccine hesitancy [DOI] 10.1080/21645515.2022.2041360 PMC 바로가기 [Article Type] Acceptance
August 2021 and the Delta variant: is mandatory vaccination of individuals against SARS-CoV-2 acceptable?2021년 8월 및 델타 변종: SARS-CoV-2에 대한 개인의 의무 예방 접종이 허용됩니까?Article Published on 2022-03-112022-09-11 Journal: Medicina clínica [Category] SARS, 변종, [키워드] Delta individual mandatory SARS-CoV-2 vaccination [DOI] 10.1016/j.medcli.2021.09.017 PMC 바로가기 [Article Type] Article
Nanobody-Functionalized Cellulose for Capturing SARS-CoV-2SARS-CoV-2 포획을 위한 나노바디 기능화 셀룰로오스Article Published on 2022-03-082022-09-11 Journal: Applied and Environmental Microbiology [Category] SARS, 변종, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Bacteria binding biological fluid Blood Cellulose cellulose binding domain cellulose binding protein complement complementary complex coronavirus COVID-19 COVID-19 pandemic cytokine Cytokines D614G variant diagnostics domain Efficiency effort exhibited filtration fluids fungi fusion protein help higher infectivity immobilization IMPROVE infected individuals intrinsic lockdowns mandatory mitigate nanobody porous preventative measures proof proof of concept provided pseudoviruses Receptor-binding domain reducing removal SARS-CoV-2 SARS-CoV-2 pseudovirus SARS-CoV-2 pseudoviruses sensitivities shown substrate the receptor-binding domain Therapeutic strategies utility vaccination Vaccinations Viral detection Viral load viral spread Viral transmission virus viruses wild type [DOI] 10.1128/aem.02303-21 PMC 바로가기 [Article Type] Article
Preventing a cluster from becoming a new wave in settings with zero community COVID-19 casesResearch Article Published on 2022-03-072022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] accumulating Affect applied average behavioural Cluster Community community transmission Containment strategy controls COVID-19 COVID-19 case defined downstream Factors growth highlighting increase in International management mandatory Mask modeling new SARS-CoV-2 outbreak Outbreaks per day Preventing Probability random reached reduce Result resulting risk supplementary material symptomatic Trajectories Travel Victoria [DOI] 10.1186/s12879-022-07180-1 PMC 바로가기 [Article Type] Research Article
Attitudes toward Vaccinations and Vaccination Coverage Rates among Dental Students in GreeceArticle Published on 2022-03-012022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, [키워드] Attitude booster Care Coverage COVID-19 dental dental school dental students dentist disease Diseases Greece healthcare personnel Hepatitis hepatitis B High-risk patients Immunity immunization Influenza mandatory Mandatory vaccination mumps National poliomyelitis Rate School student susceptibility university vaccination vaccination rate Vaccinations varicella [DOI] 10.3390/ijerph19052879 PMC 바로가기 [Article Type] Article
Prospective surveillance study in a 1,400-bed university hospital: COVID-19 exposure at home was the main risk factor for SARS-CoV-2 point seroprevalence among hospital staff1,400개 병상을 갖춘 대학 병원의 전향적 감시 연구: 집에서 COVID-19 노출이 병원 직원 사이에서 SARS-CoV-2 점 혈청 유병률의 주요 위험 요소였습니다Article Published on 2022-03-012022-09-11 Journal: Transboundary and emerging diseases [Category] SARS, 치료기술, [키워드] 95% CI adjusted administration analysed antibody association clinical symptom Clinical symptoms Compliance COVID-19 COVID-19 test evaluated Evidence evidence of first test Germany HCW HCWs healthcare healthcare worker Healthcare workers Hospital staff IgG immunoassay immunoassays mandatory nosocomial nosocomial COVID-19 Nosocomial transmission offered outbreak participant Patient care Personal protective equipment positive test result PPE Prospective prospective cohort study questionnaire recruitment reported risk risk factor SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 seroprevalence Seroepidemiologic studies Seroprevalence Surveillance test result Universal masking university with COVID-19 [DOI] 10.1111/tbed.14041 PMC 바로가기 [Article Type] Article