Understanding Gene Expression and Transcriptome Profiling of COVID-19: An Initiative Towards the Mapping of Protective Immunity Genes Against SARS-CoV-2 InfectionCOVID-19의 유전자 발현 및 전사체 프로파일링 이해: SARS-CoV-2 감염에 대한 보호 면역 유전자 매핑을 위한 이니셔티브Immunology Published on 2021-12-152022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 유전자 메커니즘, [키워드] Against Agilent Analysis Arraystar CASC18 Characteristics Cluster cluster analysis co-expression COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients dataset DEGs determine differentially expressed differentially expressed gene Differentially expressed genes disease pathogenesis DLEU2 element Gene Expression Genetic genetic factor GEO dataset globe GNAS healthy control healthy controls help identify immune immune response initiative inter-individual interactome mapping involved lncRNA mapping Microarray Mild molecular mechanism Pathway enrichment analysis performed Potential biomarker potential biomarkers PPI PPI network Profiling protective immunity protein-coding gene protein-coding genes protein-protein interaction Regulatory regulatory genes response responsible SARS-CoV-2 SARS-COV-2 infection severe COVID-19 patient SNHG20 statistical TALAM1 three groups transcriptome profiling UICLM understanding Variability volunteers was used [DOI] 10.3389/fimmu.2021.724936 PMC 바로가기 [Article Type] Immunology
SARS-CoV-2 and Implantation Window: Gene Expression Mapping of Human Endometrium and Preimplantation EmbryoReview Published on 2021-12-102022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] ACE2 ACE2 pathway Affymetrix analyzed ART biopsy BSG candidate Cohort CTSA CTSL detectable Embryo endometrial receptivity endometrium entire cohort examined expression level female genital tract gene expression level gene expression profile Human implantation infect cell knowledge mapping Microarray ovarian performed potential risk preimplantation embryos Prevalence protease protocol question receptor renin-angiotensin system reported risk SARS-CoV-2 SARS-COV-2 infection stimulated target tissue transfer understanding virus infection [DOI] 10.3390/life11121378 PMC 바로가기 [Article Type] Review
Mapping and Spatial Pattern Analysis of COVID-19 in Central Iran Using the Local Indicators of Spatial Association (LISA)Research Published on 2021-12-082022-10-28 Journal: BMC Public Health [Category] COVID-19, SARS, [키워드] addition Affect Analysis association autocorrelation calculated coronavirus COVID-19 determine distribution District Factor foci identify Imam Indicator individual infected with COVID-19 Infection information Iran Local mapping Measures pattern populations prevalence of COVID-19 public health Qom Result Spatial analysis Spread the disease virus was determined [DOI] 10.1186/s12889-021-12267-6 PMC 바로가기 [Article Type] Research
Comirnaty-Elicited and Convalescent Sera Recognize Different Spike EpitopesArticle Published on 2021-12-012022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] analysed antibody approach approved binding breadth conserved convalescent convalescent sera elicited epitope immune response indicate linear epitope linear epitopes mapping peptide peptide array pre-fusion question raise SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 vaccine sera spike Spike-specific antibody stabilized spike protein Structure the spike protein variant [DOI] 10.3390/vaccines9121419 PMC 바로가기 [Article Type] Article
Using intervention mapping to develop ‘ROSE’: an intervention to support peer workers in overdose response settingsResearch Article Published on 2021-11-272022-10-28 Journal: BMC health services research [Category] Coronavirus, MERS, SARS, [키워드] analyzed baseline can be used change characterized Community conducted COVID-19 pandemic Critical deaths develop emotional facilitate group identify impacts Intervention intervention mapping lived/living experience mapping Mental organization organizations outlined overdose response peer Peer workers positive public health Recognition Result skill Stigma Substance use supplementary material Support transcript turn working [DOI] 10.1186/s12913-021-07241-2 PMC 바로가기 [Article Type] Research Article
Evaluating the usability and acceptability of a geographical information system (GIS) prototype to visualise socio-economic and public health dataResearch Article Published on 2021-11-242022-10-28 Journal: BMC Public Health [Category] Coronavirus, MERS, SARS, [키워드] Admission analysed Analysis approach available data average barrier benefit calculated conducted demographics demonstrated determine disease Evaluating FIVE groups Health implementation improvement information Kruskal-Wallis H test mapping methodology Multiple no significant difference not affected outcome prevention prototype provided public health Public health data Research resources Result Social service statistically significant difference supplementary material SUS System Usability Scale technology understanding Usability vaccination Variation was performed [DOI] 10.1186/s12889-021-12072-1 PMC 바로가기 [Article Type] Research Article
TEG ® , Microclot and Platelet Mapping for Guiding Early Management of Severe COVID-19 CoagulopathyReview Published on 2021-11-182022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Activation addition Anticoagulant approach blood clotting caused circulating circulation clinical trials Coagulopathy consumptive coagulopathy COVID-19 COVID-19 patient disease severity dysfunction Efficacy endothelial function Endothelium Factor fibrinolysis Guiding highlight Immune cell Inflammatory Interaction intrinsic low molecular weight maintain management mapping outcome pathway physiological state Platelet platelet activation Platelets Prophylactic receptor reduced required severe COVID-19 severe COVID-19 disease therapeutic Trial von Willebrand factor vWF [DOI] 10.3390/jcm10225381 PMC 바로가기 [Article Type] Review
Management of Dental School During the COVID-19 Pandemic: Application of Intervention MappingPublic Health Published on 2021-11-162022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] activity Admission affecting applicability application approach changes in clinical setting COVID-19 COVID-19 infection COVID-19 outbreak COVID-19 pandemic dental dentistry determinant factor develop equipment evaluate Evaluation group group discussion groups indicated individual level infection control information Intervention management mapping measure Measures motivation outbreak patients Personal protective equipment Prevent prevention protection protocol reduce reduction risk School Schools theory Treatment [DOI] 10.3389/fpubh.2021.685678 PMC 바로가기 [Article Type] Public Health
Mapping Biological Risks Related to Necropsy Activities: Old Concerns and Novel Issues for the Safety of Health Professionals부검 활동과 관련된 생물학적 위험 매핑: 의료 전문가의 안전에 대한 오래된 우려 및 새로운 문제Article Published on 2021-11-132022-09-12 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 진단, [키워드] activities addition Biological biological risk carried concern Contact contact with Efficiency evaluate Health healthcare worker Healthcare workers identify issue mapping Microbiology microorganism microorganisms necropsy necropsy activity novel occupational risk pandemic performed preventive measures professional risk Risk management risk of transmission Safety sampling SARS-CoV-2 SARS-COV-2 infection [DOI] 10.3390/ijerph182211947 PMC 바로가기 [Article Type] Article
High-Resolution Linear Epitope Mapping of the Receptor Binding Domain of SARS-CoV-2 Spike Protein in COVID-19 mRNA Vaccine RecipientsCOVID-19 mRNA 백신 수용자에서 SARS-CoV-2 스파이크 단백질의 수용체 결합 도메인의 고해상도 선형 에피토프 매핑Research Article Published on 2021-11-102022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Anti-RBD IgG antibodies antibody breadth coronavirus coronavirus disease Coronavirus disease 2019 Coverage COVID-19 COVID-19 patient COVID-19 patients COVID-19 vaccine demonstrated distribution dominant epitope Establishing High-resolution immune response immune responses Immunity immunoserology in vitro individual infected individuals key factor linear Live virus mapped mapping Microarray Microarrays mRNA mRNA vaccine mRNA vaccines Mutation naïve individuals natural infection neutralization assays neutralization titer Neutralizing antibodies normalized overlapping peptide peptides Pfizer-BioNTech population immunity potency profile Protein provide RBD Receptor binding domain recipient Research Resilience respiratory SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variants sera serology severe acute respiratory syndrome Coronavirus shown similarities similarity spike Spike protein suggested the RBD the SARS-CoV-2 vaccination Vaccinations Vaccine vaccine-induced antibodies vaccine-induced antibody Vaccine-induced immunity variants of concern Variation variety Viral virus were measured [DOI] 10.1128/Spectrum.00965-21 PMC 바로가기 [Article Type] Research Article