Severe COVID‐19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotoninArticle Published on 2021-05-312023-07-02 Journal: Journal of leukocyte biology [Category] SARS, [키워드] carboxypeptidase A3 COVID‐19 mast cell SARS‐CoV‐2 Serotonin [DOI] 10.1002/JLB.4HI0221-087R PMC 바로가기
Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody비만 세포 및 호산구 활성화는 COVID-19 및 TLR 매개 바이러스 염증과 관련이 있습니다: 항 Siglec-8 항체에 대한 시사점Immunology Published on 2021-03-102022-08-31 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 진단, [키워드] Activation administration airway Airway inflammation antibody caused cell activation coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient cytokine deplete disease severity elevated eosinophil eosinophils excessive inflammation feature Health Health crisis hyperinflammation Hyperinflammatory Hyperinflammatory response Immune cell immune cells immune response immune responses implicated in vitro in vivo infiltration Inflammation Inflammatory responses inhibit innate immune cell Innate immune cells lirentelimab lung tissues mast cell Mast cells MCs mediators monoclonal antibody pathogenic Pattern recognition pattern recognition receptor Pattern recognition receptors protease Proteases reduced respiratory respiratory viral infection SARS-CoV-2 SARS-COV-2 infection sera Siglec-8 Stimulation suppressed Therapeutic approach Toll-like receptor Treatment Viral viral infection viral infections viral inflammation Viral RNA with COVID-19 [DOI] 10.3389/fimmu.2021.650331 PMC 바로가기 [Article Type] Immunology
Allergic Reactions to Current Available COVID-19 Vaccinations: Pathophysiology, Causality, and Therapeutic ConsiderationsReview Published on 2021-03-052022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Activation added adverse event allergic allergic reaction Allergic reactions allergy Anaphylactic reaction anaphylaxis antibody arising AstraZeneca Causality caused Cell complement complications contribute COVID-19 COVID-19 mRNA vaccines COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines current death degranulation Diagnosis disease effective first dose G protein-coupled receptor IgE Immunoglobulin IMPROVE incidence individuals induce Infectious disease Interaction Johnson & Johnson knowledge Kounis syndrome mast cell mechanism medication medications Moderna occur Patient Pfizer-BioNTech Polyethylene glycol potentially life-threatening Pregnancy Prevent public health question reaction reduce mortality response Safe Spread stability Surveillance Symptom therapeutic Treatment tween type I vaccination Vaccine Vaccines while with COVID-19 [DOI] 10.3390/vaccines9030221 PMC 바로가기 [Article Type] Review
Melkersson-Rosenthal Syndrome Induced by COVID-19COVID-19에 의해 유발된 멜커슨-로젠탈 증후군Case Reports Published on 2021-03-012022-09-11 Journal: The American journal of emergency medicine [Category] SARS, 유전자 메커니즘, 치료제, [키워드] characterized COVID-19 COVID-19 infection cytokine Cytokines demonstrated edema etiology facial paralysis female Fissured tongue histopathological examination induced Infection Inflammation Lower lip Lungs mast cell Mast cells Orofacial edema. paralysis Pathogenesis pathogenesis of COVID-19 Patient presenting syndrome the disease triad [DOI] 10.1016/j.ajem.2020.08.018 PMC 바로가기 [Article Type] Case Reports
Potential association of mast cells with coronavirus disease 2019비만 세포와 코로나바이러스 질병의 잠재적 연관성 2019Article Published on 2021-03-012022-09-12 Journal: Annals of allergy, asthma & immunology : official [Category] SARS, 진단, [키워드] association coronavirus disease mast cell Potential [DOI] 10.1016/j.anai.2020.11.003 PMC 바로가기 [Article Type] Article
Two Different Antibody-Dependent Enhancement (ADE) Risks for SARS-CoV-2 AntibodiesSARS-CoV-2 항체에 대한 두 가지 다른 ADE(항체 의존적 강화) 위험Immunology Published on 2021-02-242022-09-12 Journal: Frontiers in Immunology [Category] MERS, 진단, [키워드] acute respiratory distress acute respiratory syndrome ADE age animal models antibodies antibody antibody dependent enhancement ARDS Asymptomatic B-cell Betacoronavirus caused cellular tropism chemokines children chronic disease Convalescent plasma therapy coronavirus COVID-19 COVID-19 disease COVID-19 infection Critical cross-reactive antibodies Cytokine storms dendritic cells development disease disease severity elevated enhancement expand Fc receptor immature immune dysregulation implication include Infant infecting Inflammatory initial involved Lungs lymphopenia Macrophage mast cell Mast cells mechanism MERS-CoV Middle East mild flu-like symptoms MIS-C moderate Multiple Multisystem inflammatory syndrome neutrophil observation patients phagocytic cell Population Pregnancy progression Proinflammatory cytokine receptor respiratory response risk Safe SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 antibody severity of symptom Stage subset syndrome T cell therapy Vaccine Vaccines Variability virus with COVID-19 [DOI] 10.3389/fimmu.2021.640093 PMC 바로가기 [Article Type] Immunology
Stabilizing mast cells by commonly used drugs: a novel therapeutic target to relieve post-COVID syndrome?Article Published on 2020-11-042023-07-07 Journal: Drug discoveries & therapeutics [Category] SARS, [키워드] COVID-19 mast cell post-COVID syndrome pulmonary fibrosis [DOI] 10.5582/ddt.2020.03095
Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndromeMini review Published on 2020-11-012022-10-05 Journal: International Journal of Infectious Diseases [Category] SARS, 유전자 메커니즘, [키워드] activated Activation allergic Atypical cause cell activation clinical experience Course COVID-19 Cytokine storm disorder drug hyperinflammation illnesses Implications Infection Inflammation Inflammatory mast cell Mast cell activation disease Mast cell activation syndrome MCs Medical hypothesis Mortality objective observation Patient patients Prevalence prognostic Result SARS-CoV-2 Severe case Severe infection suffered symptomatic COVID-19 syndrome therapeutic treated [DOI] 10.1016/j.ijid.2020.09.016 [Article Type] Mini review
Mast Cells in Alveolar Septa of COVID-19 Patients: A Pathogenic Pathway That May Link Interstitial Edema to ImmunothrombosisImmunology Published on 2020-09-182022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, 신종인플루엔자, [키워드] alveolar injury alveolar lumen alveolar septa biopsy Cell Cell-mediated immunity cells Control COVID 19 COVID-19 diffusion edema Endothelial dysfunction expression Factor Future group Histopathology IL-4 immune responses immunothrombosis Innate immunity interleukin-4 (IL-4) interstitial lung mast cell mast cells (MC) MCs membrane pandemic patients perivascular plasma pneumocyte Pneumonia positive post-mortem lung Prevent recruited SARS-CoV-2 SARS-CoV-2 replication septa septal specimen Spread the cytokine storm Transcription upper airway upregulating [DOI] 10.3389/fimmu.2020.574862 PMC 바로가기 [Article Type] Immunology
Advances in Mast Cell Activation by IL-1 and IL-33 in Sjögren’s Syndrome: Promising Inhibitory Effect of IL-37Review Published on 2020-06-162023-08-30 Journal: International Journal of Molecular Sciences [Category] E형 간염, [키워드] cytokine IL-1 IL-33 Immunity Inflammation mast cell Sjögren syndrome [DOI] 10.3390/ijms21124297 PMC 바로가기 [Article Type] Review