maximum – Page 4 – Communicable Diseases Research

Is N95 face mask linked to dizziness and headache?

N95 안면 마스크는 현기증과 두통과 관련이 있습니까?

Article

Published on 2021-10-012022-09-11
Journal: International archives of occupational and environ [Category] SARS, 치료기술,

Epidural morphine in COVID ARDS patients with high respiratory drive: a structured summary of a study protocol for a randomised controlled trial

높은 호흡 드라이브가 있는 COVID ARDS 환자의 경막외 모르핀: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-09-162022-09-10
Journal: Trials [Category] SARS, 임상,

[키워드] 1:1 28-day mortality Abnormalities acceptance administer Administered Admission Adult patient Adult patients allocation ARDS patient aseptic technique assistant average blind Blinding both group both groups catheterization Coagulation comparator Patients control group COVID COVID 19 patient COVID 19 patients COVID-19 criteria CTRI death discharge dissemination dose doses double blind Dyspnoea element Endotracheal intubation Epidural epidural catheter Epidural morphine epidural space Escalation exclusion criteria fixed fraction greater Group allocation HCO hypoventilation Hypoxemia ICU ICU patient inclusion criteria India injection Intervention intervention group intubation involved list Local maximum mechanical ventilation Medical Science Medical Sciences Metabolic acidosis minimum morphine morphine sulphate Mortality NIV non-invasive ventilation number Nurse objective outcome Pain parameters participant Patient Patient self-induced lung injury patients with COVID19 physician Placebo protocol random randomisation randomised randomised controlled trial recruited reduce Registered registry Research respiratory respiratory acidosis Respiratory drive respiratory parameters resulting Sample size sealed second dose secondary Secondary outcomes Sedation Sepsis severe hypoxemia sitting position skin Source Study protocol sulphate supplementary material team the patient Trial ventilator parameters website with COVID-19
[DOI] 10.1186/s13063-021-05570-5 PMC 바로가기 [Article Type] Letter

SARS-CoV-2 antibody persistence in COVID-19 convalescent plasma donors: Dependency on assay format and applicability to serosurveillance

COVID-19 회복기 혈장 기증자에서 SARS-CoV-2 항체 지속성: 분석 형식 및 혈청 감시에 대한 적용 가능성에 대한 의존성

Article

Published on 2021-09-012022-09-11
Journal: Transfusion [Category] MERS, SARS, 진단, 치료기술, 치료법, 치료제,

[키워드] Abbott acute respiratory syndrome addition Algorithm Algorithms antibody antibody waning Antigen applicability association best binding Broad Institute contribute convalescent plasma coronavirus COVID-19 declining demonstrated dependency disease severity Donor greater help heterogeneous IgG include Infection levels of antibody Live virus maximum natural infection neutralization Neutralization assay neutralization assays nucleocapsid persistence PRNT pseudovirus Receptor binding domain reduce reporter Research resolution of symptoms respiratory response response duration Roche SARS-CoV-2 SARS-CoV-2 antibody screened Seven Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Severity of disease stability target tested These data total Ig variety Viral viral particle Vitalant was collected
[DOI] 10.1111/trf.16555 PMC 바로가기 [Article Type] Article

COVID-19 face masks: A new source of human and environmental exposure to organophosphate esters

COVID-19 안면 마스크: 유기인산 에스테르에 대한 인간 및 환경 노출의 새로운 출처

Article

Published on 2021-09-012022-09-11
Journal: Environment international [Category] SARS, 치료기술,

Positive selection as a key player for SARS-CoV-2 pathogenicity: Insights into ORF1ab, S and E genes

SARS-CoV-2 병원성의 핵심 플레이어로 양성 선택: ORF1ab, S 및 E 유전자에 대한 통찰력

Article

Published on 2021-09-012022-09-11
Journal: Virus research [Category] SARS, 치료기술, 치료제,

[키워드] adaptive Analysis approaches C-terminal cause codon Codons composed COVID-19 disease disease domain drug drug targeting E gene E protein Each encoded proteins Evidence evidence of Evolution functional Genes Host Host immune response Human hydrophilic in viral inhibiting insight involved likelihood maximum Maximum likelihood N-terminal domain non-structural protein non-structural proteins nonstructural protein nsp1 Nsp3 ORF1 ORF1a ORF1ab ORF1b pandemic pathogenicity performed Positive selection Protein protein domains protein-coding gene residues SARS-CoV-2 SARS-CoV-2 epidemic SARS-CoV-2 genome SARS-CoV-2 genomes Ser stability structural protein structural proteins Substitution substitutions survival target targets the S protein the SARS-CoV-2 Transcription translation transmembrane transmembrane domain Transmissibility Vaccine viral replication virulent virus vital role vital roles Wuhan Wuhan, China β-coronavirus
[DOI] 10.1016/j.virusres.2021.198472 PMC 바로가기 [Article Type] Article

Dynamical Analysis of Universal Masking on the Pandemic

팬데믹에 대한 유니버설 마스킹의 동적 분석

Article

Published on 2021-08-272022-09-10
Journal: International Journal of Environmental Research an [Category] MERS, SARS, 치료기술,

Viral and Host Transcriptomes in SARS-CoV-2-Infected Human Lung Cells

SARS-CoV-2에 감염된 인간 폐 세포의 바이러스 및 숙주 전사체

Article

Published on 2021-08-252022-09-11
Journal: Journal of Virology [Category] SARS, 유전자 메커니즘, 치료법,

[키워드] Activation activities acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect antibodies cellular characterized cholesterol coronavirus cytokine cytokine level cytokine levels Cytokine storm Cytokines demonstrated dysregulation envelope gene exacerbated exacerbating expressed expression followed by function Genes genome replication health emergency Host host responses Human Infection information lack lowest maximum metabolic imbalance metabolism Nucleocapsid gene ORF3 pathway Perspective provide receiving Research responsible RNA RNA synthesis SARS-CoV-2 sequence severe acute respiratory syndrome Coronavirus subgenomic mRNA subgenomic mRNA synthesis Support TNF Transcription transcription-regulating sequence transcriptional Transcriptome transcriptomic Treatment strategies TRS TRSs unique valine valine. viral gene viral genes viral replication Viral RNA viral RNA synthesis viral transcription
[DOI] 10.1128/JVI.00600-21 PMC 바로가기 [Article Type] Article

SPIKE-1: A Randomised Phase II/III trial in a community setting, assessing use of camostat in reducing the clinical progression of COVID-19 by blocking SARS-CoV-2 Spike protein-initiated membrane fusion

SPIKE-1: SARS-CoV-2 스파이크 단백질 개시 막 융합을 차단하여 COVID-19의 임상 진행을 줄이는 데 camostat의 사용을 평가하는 커뮤니티 환경에서의 무작위 2상/3상 시험

Letter

Published on 2021-08-192022-09-10
Journal: Trials [Category] MERS, SARS, 임상,

[키워드] 1:1 acute respiratory syndrome coronavirus apyrexia available data baseline best Biomarkers Blinding camostat clearance Clinical improvement clinical trial Community conducted control arm coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 symptom COVID-19 symptoms COVID-2019 Day defined Deterioration determined by diagnostics disease dissemination duration of illness Efficacy element eligibility criteria Eligible patients EudraCT evaluate Evidence evidence of Formal four times daily functional Guidance Health Organization health protection high risk hospital Hospital admission Hospital admissions Host include Infection initial Interactive Web Response System interim analysis Ireland IWRS Laboratory testing maximum membrane fusion moderate Mortality multicentre nasal negative swab number objective open open label Open-label Ordinal Scale outcome outcome measure overall mortality oxygen oxygen-free day Oxygenation participant Patient patient population patients with SARS-CoV-2 performed phase PK data Prevent primary care progression protection protocol provided Public Public Health Agency Public Health England qPCR questionnaire randomisation randomised randomised controlled trial receive recruit recruited recruitment reduce reducing refinement requiring supplemental oxygen Research respiratory risk RT-PCR Saliva Sample size Sample size calculations SARS-CoV-2 SARS-COV-2 infection secondary Secondary objective Secondary objectives secondary outcome measures serum antibody Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus 2 severity spike status supplemental oxygen supplementary material supplementary oxygen supportive care Swab symptom severity tablets temperature the patient TMPRSS2 translational Translational research Treatment treatment arm Trial trial protocol Trial registration typical symptom typical symptoms upper respiratory Ventilation ventilator ventilator-free day Ventilator-free days Viral Viral load viral shedding website World Health Organization
[DOI] 10.1186/s13063-021-05461-9 PMC 바로가기 [Article Type] Letter

Successful Treatment of a 39-Year-Old COVID-19 Patient with Respiratory Failure by Selective C-Reactive Protein Apheresis

선택적 C-반응성 단백질 성분채집술로 호흡부전이 있는 39세 COVID-19 환자의 성공적인 치료

Case Reports

Published on 2021-08-052022-09-11
Journal: The American journal of case reports [Category] SARS, 변종,

[키워드] activating acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adverse effect adverse effects Analysis Antibiotic therapy apheresis Autoimmune response bacterial superinfection C-reactive protein C-reactive protein (CRP Chain Reaction classical clinical condition clinically Complement pathway coronavirus COVID-19 COVID-19 patient CRP CRP level CRP levels declined discharged Dyspnea failure fatigue Fever fibrosis ICU Immunity induce Infection intensive care unit Intubated Macrophage macrophages male maximum normalized Patient PCR PCT plasma Plasma levels polymerase chain reaction poor prognosis procalcitonin pulmonary inflammation receptors referred to remained reported respiratory Respiratory failure SARS-CoV-2 SARS-COV-2 infection selective severe acute respiratory syndrome Coronavirus subsequent superinfection suppressed therapy Treatment variant venous VoC was performed
[DOI] 10.12659/AJCR.932964 PMC 바로가기 [Article Type] Case Reports

Can pharmaceutical drugs used to treat Covid-19 infection leads to human health risk? A hypothetical study to identify potential risk

Covid-19 감염을 치료하는 데 사용되는 제약 약물이 인간 건강 위험으로 이어질 수 있습니까?잠재적 위험을 식별하기위한 가상의 연구

Article

Published on 2021-07-152022-08-31
Journal: The Science of the total environment [Category] SARS, 신약개발, 치료제,

[키워드] acceptable daily intake activity adverse effect adverse effects affected Analysis approach aquatic environment assumption calculate Can carried Chloroquine Concentration Consumption contaminant contaminated surface COVID-19 COVID-19 infection COVID-19 pandemic determine drug drugs Effect estimate estimates evaluated expected Health hypothetical identify indicated Infection ingestion Lopinavir lopinavir + ritonavir maximum minimum mixture NOAEL novel Novel coronavirus pandemic PECs pharmaceutical Pharmaceuticals potential risk predicted Quotient Rapamycin RATs reduce Regular risk Risk estimation Ritonavir Rivers. Surface water Toxicity treat used to calculate water
[DOI] 10.1016/j.scitotenv.2021.146303 PMC 바로가기 [Article Type] Article