Network machine learning maps phytochemically rich “Hyperfoods” to fight COVID-19Primary Research Published on 2021-01-022022-10-04 Journal: Human Genomics [Category] MERS, 신약개발, [키워드] Accuracy Algorithm Analysis Antiviral antiviral properties approved drug calibrated candidate clinical study clinically common drug Compound coumarin COVID-19 database drug candidate drug repositioning food Gene-gene networks identify in silico indole ingredient interactomics Intervention machine machine learning Metabolic disorders network platform Precision predict predicted SARS-CoV-2 supplementary material turn Viral diseases was used [DOI] 10.1186/s40246-020-00297-x PMC 바로가기 [Article Type] Primary Research
Coronavirus Disease (COVID-19) Caused by (SARS-CoV-2) Infections: A Real Challenge for Human Gut MicrobiotaCellular and Infection Microbiology Published on 2020-12-092022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] age alteration article articles bacterial specy challenge Clinical course Clinical studies Community Concentration concerning consequence coronavirus COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 severity diabete disorder Dysbiosis Effect effort epidemiological fecal GI symptom Gut gut microbiota Health Human IBS identify Infection infection with SARS-CoV-2 Inflammatory bowel disease initial Intervention intestinal investigated mechanism metabolic disorder Metabolic disorders microbiota nutrition nutritional status obesity required Research researcher risk of infection SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 T2D thought Transmission [DOI] 10.3389/fcimb.2020.575559 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Metabolic defects in splenic B cell compartments from patients with liver cirrhosisArticle Published on 2020-10-242023-08-30 Journal: Cell Death & Disease [Category] E형 간염, [키워드] Immunological deficiency syndromes Metabolic disorders [DOI] 10.1038/s41419-020-03060-1 PMC 바로가기 [Article Type] Article
Covid-19 Quarantine: Impact of Lifestyle Behaviors Changes on Endothelial Function and Possible Protective Effect of Beetroot JuiceNutrition Published on 2020-10-212022-10-31 Journal: Frontiers in Nutrition [Category] COVID-19, [키워드] alcohol alleviate Beetroot Behavior boredom cardiovascular disease Cardiovascular health change coronavirus COVID-19 COVID-19 outbreak CVD dietary nitrate Effect effective Endothelial dysfunction endothelial function exacerbated function hypertensive Impact IMPROVE individuals Juice Metabolic disorders morbidity and mortality Nitrate nitric oxide Physical inactivity Prevent progression reducing Risk factors smoking social distancing Stress Transmission Vascular endothelium vascular health [DOI] 10.3389/fnut.2020.582210 PMC 바로가기 [Article Type] Nutrition
Prevention and Management of Type 2 Diabetes and Metabolic Syndrome in the Time of COVID-19: Should We Add a Cup of Coffee?Nutrition Published on 2020-10-062022-10-31 Journal: Frontiers in Nutrition [Category] COVID-19, [키워드] ACE2 coffee COVID-19 COVID-19 complications COVID-19 pandemic COVID-19 patient diabete diabetes dietary intake Effect evaluate Evidence Health authority healthy high risk IMPROVE increase in insulin resistance management metabolic Metabolic disorders morbidity and mortality obesity pandemic physical activity polyphenols positive prevention recent risk syndrome therapy for COVID-19 time Type type 2 diabetes [DOI] 10.3389/fnut.2020.581680 PMC 바로가기 [Article Type] Nutrition
Molecular mechanisms involved in the positive effects of physical activity on coping with COVID-19Invited Review Published on 2020-09-032022-10-31 Journal: European Journal of Applied Physiology [Category] COVID-19, MERS, SARS, [키워드] adipose adverse effect association biological processe complex interplay contribute COVID-19 Critical Cytokines disease Diseases Effect effective equipment expression general health status Health status healthy lifestyle immune system Impact infections Inflammation inflammation markers involved mechanism Metabolic disorders moderate modulated modulation molecular molecular mechanism Multiorgan obesity organ pandemic pathophysiology physical activity positive provided reduction in Regulation Result SARS-CoV2 SARS-CoV2 infection Skeletal muscle susceptibility tissue type 2 diabete viral infection viral infections was performed with COVID-19 [DOI] 10.1007/s00421-020-04484-5 PMC 바로가기 [Article Type] Invited Review
The Metabolic Changes and Immune Profiles in Patients With COVID-19Immunology Published on 2020-08-282022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress acute respiratory distress syndrome (ARDS) analyzed ARDS Bacteria Bacterial infection blood glucose C-reactive protein cardiac troponin caused CD4 CD8 cells change children children with COVID-19 circulating monocyte Co-infection Comorbidity COVID-19 D-dimer decrease diabete diabetes Disseminated intravascular coagulation Disseminated intravascular coagulation (DIC) fungi Glucose Immune profile Increased Inflammatory response Inflammatory responses interleukin-6 involved IQR lactate dehydrogenase late stage leukocytes lymphocyte metabolic metabolic disorder Metabolic disorders Mild mild COVID-19 patients MODS monocyte morbidity multiple organ dysfunction multiple organ dysfunctions (MODS) neutrophil nine Patient patients with COVID-19 procalcitonin profile RBC reduced SARS-CoV-2 serum Severe case severe COVID-19 Severe patient severe patients significantly increased susceptible syndrome T cell T cells T-lymphocytes uric acid Urine [DOI] 10.3389/fimmu.2020.02075 PMC 바로가기 [Article Type] Immunology
Nicotinamide Riboside—The Current State of Research and Therapeutic UsesReview Published on 2020-05-312022-10-30 Journal: Nutrients [Category] COVID-19, MERS, SARS, [키워드] addition addressed age-associated diseases available data benefit Bioavailability Cardiovascular disorders condition COVID-19 current Effect Efficiency elevated Evidence Health increases in Infection Metabolic disorders metabolic pathway metabolism morbidity neurodegenerative nicotinamide adenine dinucleotide nicotinamide riboside Pathogens pathophysiological conditions potential therapy precursors Prevalence Research riboside Safety SARS-CoV-2 state Supplementation Support therapeutic use translation Treatment variety [DOI] 10.3390/nu12061616 PMC 바로가기 [Article Type] Review
“The ancient and the new”: is there an interaction between cytomegalovirus and SARS-CoV-2 infection?Commentary Published on 2020-05-272022-10-30 Journal: Immunity & Ageing : I & A [Category] COVID-19, [키워드] age Clinical outcome clinical response CMV conditions cytomegalovirus feature Health heterogeneous immune function immune senescence increase Infection Interaction investigated mechanism Metabolic disorders observation older patient outcome Prevalence risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic [DOI] 10.1186/s12979-020-00185-x PMC 바로가기 [Article Type] Commentary
Development of newborn screening connect (NBS connect): a self-reported patient registry and its role in improvement of care for patients with inherited metabolic disordersResearch Published on 2017-07-192024-09-02 Journal: Orphanet Journal of Rare Diseases [Category] 대상포진, [키워드] Maple syrup urine disease Metabolic disorders NBS Connect newborn screening Patient registry Phenylketonuria Tyrosinemia [DOI] 10.1186/s13023-017-0684-3 PMC 바로가기 [Article Type] Research