Testing Antigens, Antibodies, and Immune Cells in COVID-19 as a Public Health Topic—Experience and Outlines공중 보건 주제로서 COVID-19의 항원, 항체 및 면역 세포 테스트 - 경험 및 개요Review Published on 2021-12-142022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 변종, 진단, 치료기술, [키워드] accelerated antibody tests Antigen appearance assays biological sample biological samples cells circulating COVID-19 COVID-19 pandemic COVID-19 research CRISPR detection diagnostic Diagnostic strategies diagnostics digital PCR domains ELISA evaluate flow-cytometry focus followed by Immune cell immune cells immune memory immunoassay lateral flow immunoassay left methodology Microparticle molecular diagnostics molecular test Molecular tests MONITOR new virus pandemic parameter patients platform postvaccination Public public health Research RT-PCR SARS-CoV-2 Stage Testing testing antibody triggered vaccination variant virus [DOI] 10.3390/ijerph182413173 PMC 바로가기 [Article Type] Review
Dynamics of Antibody Response to BNT162b2 mRNA COVID-19 Vaccine: A 7-Month Follow-Up StudyBNT162b2 mRNA COVID-19 백신에 대한 항체 반응의 역학: 7개월 추적 연구Article Published on 2021-12-052022-09-10 Journal: Medicina [Category] SARS, 진단, 치료기술, [키워드] (Abbott Abbott acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 All study participants amplitude anti-spike protein IgG antibodies antibody Antibody Response BNT162b2 BNT162b2 mRNA BNT162b2 mRNA COVID-19 vaccine BNT162b2 mRNA vaccine booster dose CMIA Complete comprehension conducted coronavirus COVID-19 COVID-19 vaccine division Dynamics Follow-up healthcare Healthcare workers IgG immune response immune responses Immunity immunoassay individual individuals infected individual infected with SARS-CoV-2 Infection Ireland material median median titer Microparticle MONITOR participant Participants reported respiratory response Romania SARS-CoV-2 SARS-CoV-2 IgG II Quant assay second dose sensitivity Seven severe acute respiratory syndrome Coronavirus significantly higher Sligo specificity Spike protein study participant subject the antibody response the median the SARS-CoV-2 the vaccine two groups uninfected vaccinated individual vaccination Vaccine [DOI] 10.3390/medicina57121330 PMC 바로가기 [Article Type] Article
A study of the evolution of the third COVID‐19 pandemic wave in the Athens metropolitan area, Greece, through two cross‐sectional seroepidemiological surveys: March, June 2021Research Article Published on 2021-12-042022-10-04 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome antibodies antibody Attica coronavirus coronavirus disease COVID‐19 Epidemiology Evidence Evolution febrile Greece groups healthcare facility heterogeneity highest Immunity immunoassay Immunoglobulin G increased risk Microparticle occurred pandemic Person presenting SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 Section Seroprevalence South Spike protein were measured were recorded West [DOI] 10.1002/jmv.27465 PMC 바로가기 [Article Type] Research Article
Long-term specific IgG response to SARS-CoV-2 nucleocapsid protein in recovered COVID-19 patients회수 된 CovID-19 환자에서 SARS-COV-2 뉴 클레오 캡시드 단백질에 대한 장기 특이 적 IgG 반응Article Published on 2021-12-012022-09-01 Journal: Scientific Reports [Category] SARS, 진단, 치료기술, 치료법, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus age anti-N IgG Blood blood sampling collected coronavirus coronavirus disease Coronavirus Disease (COVID)-19 correlated COVID-19 symptom IgG IgG response immune response immunoassay Immunoglobulin Immunoglobulin G Infection Infectious diseases Microparticle Patient Pneumonia positively correlated presence or absence Protein recovered COVID-19 patient Recovered COVID-19 patients respiratory respiratory specimen respiratory specimens SARS-CoV-2 detection SARS-CoV-2 nucleocapsid Seropositivity serum sample serum samples severe acute respiratory syndrome Coronavirus significantly lower specimens symptom onset Symptoms Vaccine Virology was measured [DOI] 10.1038/s41598-021-02659-4 PMC 바로가기 [Article Type] Article
Mechanisms of thrombosis in ANCA-associated vasculitisANCA 관련 혈관염에서 혈전증의 기전Review Published on 2021-12-012022-09-11 Journal: Clinical Rheumatology [Category] MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] Activated neutrophils Activation anti-neutrophil cytoplasmic antibody Anti-neutrophil cytoplasmic antibody-associated vasculitis antibodies antibody antiphospholipid antibodies antiphospholipid antibody APL Blood caused circulation clotting cocaine contribute coronavirus disease Coronavirus disease 2019 COVID-19 cytoplasmic Deep vein Deep vein thrombosis described driving drug Embolism Embolism and thrombosis endothelial injury Endothelium ENhance expressing Extracellular greater homeostatic hydralazine Injury Levamisole mechanism Microparticle NET NETosis NETs neutrophil neutrophil activation Neutrophil extracellular trap Neutrophil extracellular traps Neutrophils occur pandemic pathogenic Patient Propylthiouracil Remission report resulting risk thrombi thrombogenesis thrombosis thrombotic thrombotic event Thrombotic events tissue Tissue Factor Trigger Vascular endothelium Vasculitis venous [DOI] 10.1007/s10067-021-05790-9 PMC 바로가기 [Article Type] Review
Binding of phosphatidylserine-positive microparticles by PBMCs classifies disease severity in COVID-19 patientsPBMC에 의한 포스파티딜세린 양성 미세입자의 결합은 COVID-19 환자의 질병 중증도를 분류합니다Article Published on 2021-12-012022-09-11 Journal: Journal of Extracellular Vesicles [Category] 유전자 메커니즘, [키워드] activated addition Affect Apoptosis blood cell Blood cells Blood coagulation carried cascade CD8 CD8+ CD8+ T cells cells Clinical course Coagulation complement complement system correlated strongly COVID-19 COVID-19 diagnosis COVID-19 patient COVID-19 patients disease severity distribution dying cells Frequency gene expression signature immune cells immune dysfunction Inflammation Inflammatory responses initial investigated Laboratory leucocyte lymphocyte Lymphocytes lymphopenia marker memory T cells Microparticle occur Patient PBMC PBMCs PD-L1 Phosphatidylserine Platelet platelet-derived microparticle Platelets SARS-CoV-2 severe lymphopenia T cell T cells Thromboinflammation thrombotic [DOI] 10.1002/jev2.12173 PMC 바로가기 [Article Type] Article
Dual electrochemical sensing of spiked virus and SARS-CoV-2 using natural bed-receptor (MV-gal1)천연 침대 수용체(MV-gal1)를 사용한 스파이크 바이러스 및 SARS-CoV-2의 이중 전기화학적 감지Article Published on 2021-11-262022-09-10 Journal: Scientific Reports [Category] MERS, 치료기술, [키워드] addition antibody AuNP binding Biological techniques COVID-19 detect dropping dual glycan identify Materials science Microparticle platform point of care probe receptor SARS-CoV-2 SARS-CoV-2 antigen Screen sensor specificity sugar turn Vesicle Viral viral particle Viral particles virus [DOI] 10.1038/s41598-021-02029-0 PMC 바로가기 [Article Type] Article
Waning of Anti-spike Antibodies in AZD1222 (ChAdOx1) Vaccinated Healthcare Providers: A Prospective Longitudinal StudyPreventive Medicine Published on 2021-11-252022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome Administered affecting age Analysis antibody antibody kinetics Antibody titer AstraZeneca vaccine average AZD1222 binding antibody unit blood sample BMI booster dose Breakthrough infection breakthrough infections ChAdOx1 chadox1 ncov19 vaccine ChAdOx1 vaccine chemiluminescence collected conducted coronavirus Coronavirus disease 2019 COVID vaccine COVID-19 COVID-19 vaccine Covishield dose doses Factor Factors first dose geometric globe healthcare facility Healthcare professional history IgG IgG titer immunoassay Immunoglobulin intramuscularly Kinetics linear mixed model longitudinal material Medical Science men Microparticle mixed model Nurses obese occurred Older overweight pandemic participant Person potential benefit Prospective Research Result SARS-CoV-2 SARS-COV-2 infection second dose seroreversion Seven shown tested the receptor-binding domain the spike protein the vaccine titer vaccination Vaccine vaccine dose viral particle women [DOI] 10.7759/cureus.19879 PMC 바로가기 [Article Type] Preventive Medicine
The Compass-COVID19-ICU Study: Identification of Factors to Predict the Risk of Intubation and Mortality in Patients with Severe COVID-19Conference abstract Published on 2021-11-242022-10-05 Journal: Blood [Category] 바이오마커, [키워드] activated Activation age Antigen Biomarker C3a C5a Clinical outcome complement composed conducted COVID-19 Critical Cytokine storm death diagnostic duration of hospitalization Endothelial cell Factor feasible fibrinogen funding Hospitalization hospitals hypercoagulability ICU ICU admission identification IL-6 in some induce Inflammation intensive care intubation management mechanical ventilation Microparticle Mortality mortality rate Multivariate analysis P-selectin Patient patients patients with COVID-19 Platelet predicted Predictive predictors procoagulant prognostic Protein protein S Prothrombin time risk SARS-COV-2 infection Sensitivity and specificity TFPI therapeutic intervention thrombin tissue unmet need were assessed worsening [DOI] 10.1182/blood-2021-146483 [Article Type] Conference abstract
In Covid-19 Infection, Plasma Extracellular Vesicle Tissue Factor Activity Does Not Correlate with D-Dimer LevelsConference abstract Published on 2021-11-232022-10-05 Journal: Blood [Category] 바이오마커, [키워드] absence Activation activities activity acute respiratory syndrome Admission affected Analysis analyzed antibody Anticoagulant Antigen assays Biomarker Blood Cell circulating Coagulation Coagulopathies collected complex conducted Contact contribute corn correlation Cytokines D-dimer D-dimer level damaged disease disease severity dissociate download elevated evaluate expression extrinsic Factor fatality figure generate group healthy healthy control heparins highest Hospitalization hospitalized patient identify increase increase in induce Infection inhibitor inhibitory intensive care intrinsic Level mechanical ventilation mechanism Microparticle Mortality Neutrophil extracellular trap nucleic acid occur occurred organized outcome outcomes parameter pathway Patient performed plasma plasma samples positive patient processed procoagulant activity reduced released reported responsible SARS-CoV-2 selective severity shown significant difference the disease thrombin thrombosis tissue Treatment Trigger trypsin Variability Vesicle were measured while [DOI] 10.1182/blood-2021-153142 [Article Type] Conference abstract