Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAsArticle Published on 2022-06-012023-07-08 Journal: Food and chemical toxicology : an international jo [Category] COVID19(2023년), [키워드] Cancer Exosomes G-quadruplexes MicroRNAs SARS-CoV-2 mRNA vaccines type I interferon response [DOI] 10.1016/j.fct.2022.113008 PMC 바로가기
Target and drug predictions for SARS-CoV-2 infection in hepatocellular carcinoma patients간세포암 환자에서 SARS-CoV-2 감염에 대한 표적 및 약물 예측Article Published on 2022-05-312022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analysis Cell clinician Complication coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Critical dataset datasets differentially expressed differentially expressed gene drug drugs effective effective drug effective drugs epithelial cell functional genomes HCC HCC patient HCC patients Hepatocellular carcinoma hub genes Human identify Ilomastat infected with SARS-CoV-2 Interaction Kyoto lung epithelial microRNA MicroRNAs miRNA molecular Ontology pandemic pathway Patient patients Protein protein-protein interaction provide Research reveal SARS-CoV-2 SARS-COV-2 infection selected severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 synergistic synergistic effect target terminology therapeutic transcription factor transcriptomic analysis Treatment was performed with COVID-19 [DOI] 10.1371/journal.pone.0269249 PMC 바로가기 [Article Type] Article
Study of microRNA expression in Salmonella Typhimurium-infected porcine ileum reveals miR-194a-5p as an important regulator of the TLR4-mediated inflammatory response살모넬라 타이피무리움에 감염된 돼지 회장에서의 마이크로RNA 발현 연구는 TLR4 매개 염증 반응의 중요한 조절자로 miR-194a-5p를 밝혀냈다.Article Published on 2022-05-212024-08-21 Journal: Vet Res [Category] 살모넬라증, [키워드] CRISPR-Cas9 ileum Immunity Infection Inflammation MicroRNAs miRNA-seq pig. salmonellosis Toll-like receptor
The expression patterns of MALAT-1, NEAT-1, THRIL, and miR-155-5p in the acute to the post-acute phase of COVID-19 diseaseCOVID-19 질병의 급성기에서 후기 급성기 MALAT1, NEAT1, THRILL 및 miR-155-5p의 발현 패턴Article Published on 2022-05-012022-09-11 Journal: The Brazilian journal of infectious diseases : an [Category] COVID19(2023년), SARS, 바이오마커, 진단, [키워드] acute COVID-19 acute phase addition Analysis Biomarker COVID-19 COVID-19 diagnosis COVID-19 disease COVID-19 infection diagnose diagnosis of COVID-19 disease evaluated expression level expression levels expression pattern expression patterns hallmark hallmarks healthy control healthy individual Infection Inflammation Inflammatory factor inflammatory factors Long Long non-coding RNAs MicroRNAs miR-150 miR-155 MONITOR mononuclear cell ncRNA ncRNAs non-coding RNA Non-coding RNAs Pathogenesis pathogenesis of COVID-19 Patient PBMC peripheral Peripheral blood real-time PCR assay RNA ROC Curve selected severity of COVID-19 significantly increased significantly lower the SARS-CoV-2 THRIL Total total RNA [DOI] 10.1016/j.bjid.2022.102354 PMC 바로가기 [Article Type] Article
Differentially expressed plasmatic microRNAs in Brazilian patients with Coronavirus disease 2019 (COVID-19): preliminary resultsOriginal Article Published on 2022-03-172023-06-15 Journal: Molecular biology reports [Category] COVID19(2023년), MERS, SARS, [키워드] Biomarkers COVID-19 epigenomics MicroRNAs SARS-CoV-2 [DOI] 10.1007/s11033-022-07338-9 PMC 바로가기 [Article Type] Original Article
Assessment of Association between miR-146a Polymorphisms and Expression of miR-146a, TRAF-6, and IRAK-1 Genes in Patients with BrucellosisArticle Published on 2022-03-012023-06-22 Journal: Molecular biology reports [Category] 조류인플루엔자, [키워드] brucellosis Cytokines MicroRNAs miR-146a. Polymorphisms [DOI] 10.1007/s11033-021-07014-4
MiRNA: Biological Regulator in Host-Parasite Interaction during Malaria Infection미RNA: 말라리아 감염 중 숙주-기생충 상호작용의 생물학적 조절자Review Published on 2022-02-192024-08-08 Journal: International Journal of Environmental Research and Public Health [Category] 말라리아, [키워드] Biomarkers Extracellular vesicles Gene Expression MicroRNAs MicroRNAs biogenesis [DOI] 10.3390/ijerph19042395 PMC 바로가기 [Article Type] Review
MicroRNA let-7 and viral infections: focus on mechanisms of actionReview Published on 2022-02-142022-10-31 Journal: Cellular & Molecular Biology Letters [Category] COVID-19, [키워드] adaptive Affect Cancer Cell cells cellular pathway cellular processes concerning Critical cytoplasm Defense expression function functions Host host antiviral response human cell human diseases immune cells in viral involved knowledge Let-7 lipids mechanism mechanisms membrane-bound MicroRNAs miRNA miRNAs modulate mRNAs Pathogenesis Proteins Regulatory role released Structure suggested target Target genes therapeutic strategy Transport Vesicle viral infection viral infections viral replication viruses [DOI] 10.1186/s11658-022-00317-9 PMC 바로가기 [Article Type] Review
Association of cardiometabolic microRNAs with COVID-19 severity and mortalityCOVID-19 중증도 및 사망률과 심혈관 대사성 microRNA의 연관성Fast-Track Original Article Published on 2022-02-102022-09-10 Journal: Cardiovascular Research [Category] 바이오마커, [키워드] acute phase acute phase response age association Biomarkers Blood BMI candidate Candidates cardiometabolic Cell cell activation Chain Reaction circulating miRNA circulating miRNAs Cohort combinations coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patient COVID-19 severity D-dimer determine differentially expressed endothelial healthy control healthy controls hepatocyte ICU intensive care lead liver longitudinal samples marker microRNA MicroRNAs Mild miR-122 miRNA miRNAs moderate Mortality Multiorgan myeloperoxidase Myocyte neutrophil neutrophil count neutrophil counts neutrophil degranulation outcome parameter patients performed plasma Platelet polymerase chain polymerase chain reaction positive predictor Protein proteomics proteomics data Quantitative reduced reflect reverse transcription reverse transcription quantitative polymerase chain reaction RNA-Seq SARS-CoV-2 selected severity tissue tissue injury Trajectories troponin with COVID-19 [DOI] 10.1093/cvr/cvab338 PMC 바로가기 [Article Type] Fast-Track Original Article
A Differential Signature of Circulating miRNAs and Cytokines Between COVID-19 and Community-Acquired Pneumonia Uncovers Novel Physiopathological Mechanisms of COVID-19COVID-19와 지역사회 획득 폐렴 사이의 순환하는 miRNA와 사이토카인의 차등 서명은 COVID-19의 새로운 생리병리학적 메커니즘을 밝혀냅니다Immunology Published on 2022-01-112022-09-11 Journal: Frontiers in Immunology [Category] 바이오마커, 치료제, [키워드] Analysis cohort of patient Combination community-acquired pneumonia coronavirus disease Coronavirus disease 2019 COVID-19 CXCL12 cytokine Cytokines dysregulated effort EGFR Elderly patient elderly patients IL-10 IL-17 independent Infectious disease life-threatening mechanism mechanisms MicroRNAs Mild miR-30 miR-30a-5p miRNA miRNAs multiple comorbidities Multivariate analysis novel Pathologies patients Physiopathological plasma Plasma levels plasma miRNA plasma protein Pneumonia pneumonias profile profiles severe COVID-19 patients signature Significant significant differences significantly soluble proteins subsequent validation target targets [DOI] 10.3389/fimmu.2021.815651 PMC 바로가기 [Article Type] Immunology