Soluble urokinase Plasminogen Activator Receptor (suPAR) levels are predictive of COVID-19 severity: an Italian experienceResearch article Published on 2022-09-012022-10-05 Journal: Clinical immunology (Orlando, Fla.) [Category] 바이오마커, 진단, [키워드] activator BPAP calprotectin cannula Chorus circulating Concentration correlation COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity CPAP disease severity evaluate expressed helping IL-1β IL-6 Inflammatory inflammatory markers IQR Italian Italy lymphocyte counts marker Mask mortality rate neutrophil neutrophil count NLR P/F ratio plasminogen positive correlation Predictive prognostic biomarker Ratio representing respiratory Respiratory Support Result risk Risk assessment shown suPAR survival rate tested the disease therapy TNF-α were used [DOI] 10.1016/j.clim.2022.109091 [Article Type] Research article
Evaluating the Performance of Centers for Disease Control and Prevention COVID-19 Community Levels as Leading Indicators of COVID-19 MortalityArticle Published on 2022-09-012022-11-16 Journal: Annals of internal medicine [Category] Fulltext, MERS, 변종, [키워드] Analysis CDC center Community complicate Control Council COVID-19 death diagnostic elevated evaluate Evaluating Evolution exceeded Hospital admission Hospital admissions hospitalizations Immunity IMPROVE Indicator interquartile range IQR leading Level lower mortality median medium Metrics Mortality mortality rate mortality risk National Negative predictive value outcome performance Positive predictive value Predictive predictor prevention public health Ratio reported risk sensitivity specificity state Support Surveillance threshold time Viral variants [DOI] 10.7326/M22-0803 PMC 바로가기
COVID-19 vaccination, incidence, and mortality rates among indigenous populations compared to the general population in Brazil: Describing trends over timeResearch article Published on 2022-09-012022-10-05 Journal: The Lancet Regional Health - Americas [Category] 진단, [키워드] absence Adults age available data Brazil chronic Coverage COVID-19 COVID-19 incidence COVID-19 pandemic COVID-19 vaccination cumulative cumulative mortality death decrease Describing detrimental Effectiveness extreme finding funding General population health inequities Health inequity heterogeneity implementation incidence incidence rate incidence rates Indigenous populations information Isolation Ministry of Health Mortality mortality rate Older Population populations regions reported resource respond supported the vaccine Trends over time vaccination Vaccination strategy Vaccine [DOI] 10.1016/j.lana.2022.100319 [Article Type] Research article
Characteristics and predictors of outcomes of critically Ill children with SARS-CoV-2 infection – the PICU experienceArticle Published on 2022-09-012022-11-15 Journal: Jornal de pediatria [Category] SARS, 진단, [키워드] Administered Admission age Care children Clinical characteristics Comorbidity COVID COVID-19 Critically ill Critically ill children CRP D-dimer demographic died discharged distress elevated Factor Fever hospital Hospitalized ICU Ill Infant Infants infected children inflammatory markers intensive care Intervention IVIG Laboratory parameters Lactate less majority mechanical ventilation MIS-C mortality rate Older outcome outcomes Patient patients pediatric performed PICU predictor Predictors of unfavorable outcome. procalcitonin prospective observational study required SARS-CoV-2 SARS-COV-2 infection severe COVID-19 patients Shock steroid subjects Support the patient Treatment ventilator were recorded [DOI] 10.1016/j.jped.2021.12.006 PMC 바로가기
The effects of high dose vitamin D supplementation as a nutritional intervention strategy on biochemical and inflammatory factors in adults with COVID-19: Study protocol for a randomized controlled trialCOVID-19 성인의 생화학적 및 염증 인자에 대한 영양 중재 전략으로서 고용량 비타민 D 보충제의 효과: 무작위 대조 시험을 위한 연구 프로토콜Article Published on 2022-09-012022-09-11 Journal: Nutrition and health [Category] 바이오마커, 임상, [키워드] All participant All participants Analysis baseline biochemical blood count both groups CBC changes in chest CT scan classification clinical outcomes complete blood count conducted confounders control group covariance COVID-19 Descriptive statistics diagnosis of COVID-19 double-blind duration of hospitalization Effect erythrocyte sedimentation erythrocyte sedimentation rate ESR Evidence followed by gel heart High dose hospitalized COVID-19 patients hs-CRP Imam in both groups Inflammation Inflammatory factor Inflammatory marker inflammatory markers intervention group Iran Laboratory life liver Mashhad mortality rate New York nutritional intervention parameter participant Patient performed Placebo protocol Quality of life randomization Randomized Randomized controlled trial receive recorded renal Reza risk factor RT-PCR sedimentation rate serum serum vitamin D shown study period Trial undergo Vitamin D Vitamin D supplementation with COVID-19 [DOI] 10.1177/02601060221082384 PMC 바로가기 [Article Type] Article
Comparison of the effect of intravenous dexamethasone and methylprednisolone on the treatment of hospitalized patients with COVID-19: a randomized clinical trialRandomized Controlled Trial Published on 2022-09-012022-10-04 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 바이오마커, 임상, 치료법, [키워드] addition Admission age analysis of variance analyzed assigned confidence interval COVID-19 Dexamethasone doses duration of hospitalization Effect Effectiveness enrolled Hospital stay Hospitalization hospitalized patient hyperglycemia hypokalemia Inpatient intensive care intravenous leukocyte Lymphocyte count Methylprednisolone methylprednisolone group moderate Mortality mortality rate Oxygen therapy Patient Primary outcome protocol randomized clinical trial Randomly Result secondary outcome severe COVID-19 significantly SPSS statistically significant t-test therapeutic Treatment two group with COVID-19 [DOI] 10.1016/j.ijid.2022.07.019 PMC 바로가기 [Article Type] Randomized Controlled Trial
High-Dose versus Low-Dose Corticosteroids in COVID-19 Patients: a Systematic Review and Meta-analysisResearch article Published on 2022-09-012022-10-05 Journal: Journal of cardiothoracic and vascular anesthesia [Category] COVID19(2023년), SARS, 비임상, 임상, [키워드] Admission Analysis certainty of evidence Clinical efficacy coronavirus Corticosteroid Corticosteroids COVID-19 COVID-19 patients demonstrated Dexamethasone did not reduce dose evaluate Evidence group heterogeneity High-dose higher risk Hospital stay hyperglycemia ICU IMPROVE incidence Inconclusive infection rate intensive care low-dose corticosteroid low-dose corticosteroids measurement mechanical ventilation Meta-analysis Methylprednisolone mortality rate no significant difference objective observational study participant patients positive randomized clinical trial Randomized controlled trial Respiratory Support Result review SARS-CoV-2 SARS-CoV-2 PCR setting significant difference systematic review Trial trial sequential analysis [DOI] 10.1053/j.jvca.2022.05.011 [Article Type] Research article
COVID-19 induced Diabetes: A novel presentationReview article Published on 2022-09-012022-10-05 Journal: Diabetes research and clinical practice [Category] SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] affected assumed Atypical Beta cells biochemical biochemical pathway Case series cause caused Cell cell damage Complication COVID COVID-19 COVID-19 pandemic COVID-19 patient critically ill patients Cross-sectional studies detect diabete diabetes Diabetes Mellitus Diagnosis Diagnostic Criteria dysregulation Follow-up Glucose Google Scholar homeostasis implication include Infection insulin resistance management mechanisms meta-analyses Mortality mortality rate outcome parameter Pathogenesis pathophysiological mechanism Patient Prognosis Result risk factor SARS-CoV-2 significantly higher trajectory type 2 diabetes was performed [DOI] 10.1016/j.diabres.2022.110034 [Article Type] Review article
Fatality assessment and variant risk monitoring for COVID-19 using three new hospital occupancy related metricsResearch article Published on 2022-09-012022-10-05 Journal: EBioMedicine [Category] SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] analyses average Case fatality rate (CFR) caused CFR changes in country COVID-19 COVID-19 hospitalization COVID-19 severity death described discharge early stage Estimated fatality Fatality rate finding funding hospital Hospital mortality Hospital occupancy mortality rate (HOMR) mathematical Metrics mortality rate Multiple omicron pandemic Range-to-mean ratio (R/M) Ratio of hospital occupancy to cases (HOCR) Ratio of total deaths to hospital occupancy (TDHOR) risk severity of COVID-19 variant Variation were used [DOI] 10.1016/j.ebiom.2022.104225 [Article Type] Research article
Mutations in the nonstructural proteins of SARS-CoV-2 may contribute to adverse clinical outcome in patients with COVID-19Research article Published on 2022-09-012022-10-05 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Amino acid Clinical course Clinical outcome Cluster contribute COVID-19 enrolled FIVE genome sequence Infection mortality rate Mutation nonstructural protein Nsp15 Nsp3 oxygen flow rate Patient patients with COVID-19 positive Primary outcome required Result SARS-CoV-2 secondary outcome selective severity the disease the S protein two groups virulence were infected with COVID-19 [DOI] 10.1016/j.ijid.2022.05.010 [Article Type] Research article