Impact of glycan cloud on the B-cell epitope prediction of SARS-CoV-2 Spike proteinArticle Published on 2020-09-042022-10-04 Journal: NPJ Vaccines [Category] 진단, [키워드] Alter Analysis antibody antibody-based therapy B-cell epitope China diagnostics epitope flexible glycosylation pattern heterogeneous homogeneous identify Impact inaccessible N-glycosylation outbreak pandemic proportions Protein Receptor binding domain resulting S-protein S2 subunit SARS-CoV-2 spike spread to target the S1 subunit the Spike trimeric Vaccine Vaccine development Vaccines were used [DOI] 10.1038/s41541-020-00237-9 PMC 바로가기 [Article Type] Article
Hepatitis B Virus Exploits ERGIC-53 in Conjunction with COPII to Exit CellsArticle Published on 2020-08-122023-06-03 Journal: Cells [Category] B형 간염, Fulltext, [키워드] COPII ERGIC-53 HBV HBV assembly HBV egress LMAN-1 N-glycosylation Sec24A [DOI] 10.3390/cells9081889 PMC 바로가기 [Article Type] Article
N-glycosylation of infectious bronchitis virus M41 spike determines receptor specificityResearch Article Published on 2020-06-262022-10-30 Journal: The Journal of General Virology [Category] Coronavirus, [키워드] attachment protein binding comparable coronavirus Critical determine expressed generate genetics growth host cells IBV Infectious Bronchitis Virus initiated investigated knock-out M41 mutant mutants Mutation N-glycosylation N-glycosylation site RBD RBDs receptor Receptor binding domain shown sialic acid specificity Spike protein the RBD tissue virus virus replication virus–host interactions wild-type [DOI] 10.1099/jgv.0.001408 PMC 바로가기 [Article Type] Research Article
Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infectionsArticle Published on 2019-03-052023-06-14 Journal: Proceedings of the National Academy of Sciences of [Category] Fulltext, 신종인플루엔자, [키워드] hemagglutinin stem-specific antibody influenza vaccines monoglycosylated influenza split virus vaccine N-glycosylation [DOI] 10.1073/pnas.1819197116 PMC 바로가기
Multiple Roles of Glycans in Hematological MalignanciesReview Published on 2018-09-062023-08-30 Journal: Frontiers in Oncology [Category] E형 간염, [키워드] glycan glycosaminoglycan glycosphingolipid Hematological malignancies lectin N-glycosylation O-glycosylation [DOI] 10.3389/fonc.2018.00364 PMC 바로가기 [Article Type] Review
Iminosugars: Promising therapeutics for influenza infectionArticle Published on 2017-09-032023-06-14 Journal: Critical reviews in microbiology [Category] Fulltext, 신종인플루엔자, [키워드] hemagglutinin iminosugars Influenza N-glycosylation neuraminidase [DOI] 10.1080/1040841X.2016.1242868 PMC 바로가기
Re-emergence of H3N2 strains carrying potential neutralizing mutations at the N-linked glycosylation site at the hemagglutinin head, post the 2009 H1N1 pandemicResearch Article Published on 2016-08-082023-05-25 Journal: BMC Infectious Diseases [Category] Fulltext, 신종인플루엔자, [키워드] escape mutation H3N2 HA globular head influenza A N-glycosylation [DOI] 10.1186/s12879-016-1738-1 PMC 바로가기 [Article Type] Research Article
Biochemical composition of haemagglutinin-based influenza virus-like particle vaccine produced by transient expression in tobacco plantsArticle Published on 2015-06-012023-06-25 Journal: Plant Biotechnology Journal [Category] 신종인플루엔자, [키워드] Haemagglutinin Lipid raft N-glycosylation plant virus-like particles [DOI] 10.1111/pbi.12301
Studies on membrane topology, N-glycosylation and functionality of SARS-CoV membrane proteinResearch Published on 2009-06-182022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] acute respiratory syndrome Amino acid Analysis biochemical C-terminal Cell culture conserved coronavirus Coronaviruses ectodomain endodomain ERGIC expressing found functional glycosylated Golgi complex immunofluorescence immunogenic Interaction M protein membrane membrane protein N-glycosylation N-glycosylation site N-terminal recruitment SARS-CoV SARS-CoV M Surface glycoprotein Topology transmembrane transmembrane domain Viral particles viral spike protein virion virus [DOI] 10.1186/1743-422X-6-79 PMC 바로가기 [Article Type] Research