Interplay between Klebsiella pneumoniae producing KPC-31 and KPC-3 under treatment with high dosage meropenem: a case report고용량 메로페넴으로 치료 중인 KPC-31을 생성하는 Klebsiella pneumoniae와 KPC-3 사이의 상호작용: 증례 보고Case Reports Published on 2022-03-012022-09-11 Journal: European Journal of Clinical Microbiology & Infect [Category] 변종, [키워드] avibactam carbapenem Case report Ceftazidime Ceftazidime-avibactam collected conditions conserved dosage Evolution Fever High dose Hospitalization Illumina Infection Klebsiella pneumoniae KPC meropenem Nanopore nanopore sequencing occurred Patient performed pneumoniae presenting producing Pulmonary infection remained Rome SARS-CoV2 selected Sequencing strain Strains susceptible Symptoms the patient Therapies treated Treatment Umberto variant were used whole-genome sequencing [DOI] 10.1007/s10096-021-04388-y PMC 바로가기 [Article Type] Case Reports
High throughput sequencing based direct detection of SARS-CoV-2 fragments in wastewater of Pune, West India인도 서부 푸네의 폐수에서 SARS-CoV-2 조각의 높은 처리량 시퀀싱 기반 직접 검출Article Published on 2022-02-102022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] affected Analysis ARTIC protocol asymptomatic individual Asymptomatic individuals circulating Clinical data clinically concern conducted COVID-19 pandemic delta variant detect Early detection epidemiological Epidemiology escaped hypothesised identify India infections Lineage metagenomics Mutation mutations nanopore sequencing nsp14 nucleic acid Occurrence pandemic rapid increase reported responsible SARS-CoV-2 SARS-CoV-2 infected individuals SARS-CoV-2 mutation SARS-CoV-2 mutations SARS-CoV-2 nucleic acid SARS-CoV-2 virus Sequencing utility valuable resource variant virus wastewater West [DOI] 10.1016/j.scitotenv.2021.151038 PMC 바로가기 [Article Type] Article
Analytical performance comparison of four SARS-CoV-2 RT-qPCR primer-probe sets for wastewater samples폐수 샘플에 대한 4개의 SARS-CoV-2 RT-qPCR 프라이머-프로브 세트의 분석 성능 비교Article Published on 2022-02-012022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, [키워드] addition analytical sensitivity CCDC collected Community conducted COVID-19 current effective Epidemiology evaluated Factor feasibility highest molecular Nanopore nanopore sequencing plasmids positive Prevalence primer primer-probe set primer-probe sets qPCR qPCR assays quantified Quantitative Quantitative analysis reliability reproducibility RT-qPCR RT-qPCR assay RT-qPCR assays SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RNA detection sensitivity Surveillance wastewater Wastewater-based epidemiology [DOI] 10.1016/j.scitotenv.2021.150572 PMC 바로가기 [Article Type] Article
Salmonella Paratyphi Infection: Use of Nanopore Sequencing as a Vivid Alternative for the Identification of Invading BacteriaArticle Published on 2021-12-312024-09-07 Journal: Prague Med Rep [Category] 살모넬라증, [키워드] Enteric fever nanopore sequencing paratyphoid fever pathogen identification Salmonella PMC 바로가기
CalmBelt: Rapid SARS-CoV-2 Genome Characterization for Outbreak TrackingMedicine Published on 2021-12-142022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] caused characterization clade clinical samples clinically Cluster Clusters COVID-19 COVID-19 pandemic Critical demonstrated determine diagnostic draft epidemiological Establishing generate Genome GISAID Health healthcare healthcare worker hospital identify Impact Increasing infection control information Laboratory lack lineages nanopore sequencing outbreak outbreak tracking patient safety potential transmission Rapid required SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 variant sequence Sequence analysis Sequencing sequencing technology Spread Transmission transmission pattern web application whole genome Whole genome sequencing [DOI] 10.3389/fmed.2021.790662 PMC 바로가기 [Article Type] Medicine
Rapid identification of pathogens associated with ventilator-associated pneumonia by Nanopore sequencing인공호흡기 관련 폐렴과 관련된 병원체의 신속한 식별을 위한 나노포어 시퀀싱Research Published on 2021-12-102024-07-30 Journal: Respiratory Research [Category] 폐렴구균 감염증, [키워드] Clinical identification method endotracheal aspirate nanopore sequencing pathogen identification Ventilator-associated pneumonia [DOI] 10.1186/s12931-021-01909-3 PMC 바로가기 [Article Type] Research
Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units확장된 COVID-19 중환자실에서 2차 감염 치료 및 병원 전파 감지를 개선하기 위한 호흡기 메타유전체학의 잠재력 평가Research Published on 2021-11-172022-09-10 Journal: Genome Medicine [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] 95% CI absence added Antibiotic resistance Antibiotics approach Aspergillus fumigatus Bacterial carried clinical clinical assessment COVID-19 COVID-19 pandemic Critical care Culture detect evaluated Evaluating expansion Genome genomic Genomic surveillance ICU ICUs IMPROVE increased risk Infection infection control infections initial intensive care unit intubated patient Laboratory MDR modify Nanopore nanopore sequencing nosocomial Nosocomial transmission outbreak pathogen pathogen detection Pathogens Patient pneumoniae positive presence or absence provide quantitative PCR reported Research respiratory respiratory sample Respiratory samples Result SARS-CoV-2 pandemic Secondary infection Sequencing sequencing data Seven supplementary material Surveillance translated Transmission Treatment [DOI] 10.1186/s13073-021-00991-y PMC 바로가기 [Article Type] Research
Nanopore sequencing of SARS-CoV-2: Comparison of short and long PCR-tiling amplicon protocolsSARS-COV-2의 나노 포어 시퀀싱 : 짧고 긴 PCR 타일 앰플리콘 프로토콜의 비교Research Article Published on 2021-10-292022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, [키워드] Amplicon amplicons Analysis approach artefact Bacterial Contamination COVID-19 pandemic Decision making demonstrated effective evaluated fraction genome coverage Health Health policy mutant Nanopore nanopore sequencing outperform problem problems protocol provide reads RNAs SARS-CoV-2 genome sequences SARS-CoV-2 variants Sequencing sequencing reads the SARS-CoV-2 the SARS-CoV-2 genome variant Viral viral genome [DOI] 10.1371/journal.pone.0259277 PMC 바로가기 [Article Type] Research Article
eccDNAs are apoptotic products with high innate immunostimulatory activity Research Published on 2021-10-222022-10-05 Journal: Nature [Category] 유전자 메커니즘, [키워드] Apoptosis apoptotic biogenesis clinical implication cytosolic demonstrated dependent on described DNA DNA fragmentation element full-length function Genome Genomic DNA immune response immunostimulant immunostimulatory independent inducer mechanism nanopore sequencing pathway purified random sequence sequenced STING [DOI] 10.1038/s41586-021-04009-w [Article Type] Research
Nanopore Genome Sequencing and Variant Analysis of the Susceptible Candida auris Strain L1537/2020, Salvador, Brazil감수성 칸디다 아우리스 균주 L1537/2020의 나노포어 게놈 시퀀싱 및 변이체 분석, 살바도르, 브라질MycopathologiaGENOME Published on 2021-10-202022-09-10 Journal: Mycopathologia [Category] MERS, SARS, 변종, [키워드] Analysis Brazil Candida Candida auris COVID-19 patient De novo genome assembly Emerging pathogen Genetic genome sequence nanopore sequencing performed reported strain Strains susceptible variant Variant calling [DOI] 10.1007/s11046-021-00593-7 PMC 바로가기 [Article Type] MycopathologiaGENOME