organ dysfunction – Page 4 – Communicable Diseases Research

Immune-Mediated Glycocalyx Remodeling in Hospitalized COVID-19 Patients

Short Communication

Published on 2021-11-182022-10-31
Journal: Cardiovascular Drugs and Therapy [Category] COVID-19, MERS, SARS,

[키워드] acute respiratory distress acute respiratory syndrome addition ARDS association circulating Clinical deterioration component contribute coronavirus disease Coronavirus-2 COVID-19 COVID-19 patient Degradation disease elevated glycocalyx hallmark healthy control hospitalized COVID-19 patient IL-6 immune dysfunction immune mechanism immune responses Infection Inflammation Inflammatory cytokine IQR mammalian cells marker Mortality observational study occur offer organ dysfunction pathobiology of COVID-19 pathogenesis of COVID-19 phasic progression prospective cohort study remodeling Result risk stratification SARS-CoV-2 SARS-CoV-2 infections SDC1 Sepsis syndrome therapeutic approaches thrombosis TNFα Vascular vascular dysfunction Vascular injury vessel with COVID-19
[DOI] 10.1007/s10557-021-07288-7 PMC 바로가기 [Article Type] Short Communication

Hafnia alvei Pneumonia: A Rare Cause of Infection in a Patient with COVID-19

Case Report

Published on 2021-11-172022-10-29
Journal: Microorganisms [Category] COVID-19,

Effect of Intubation Timing on the Outcome of Patients With Severe Respiratory Distress Secondary to COVID-19 Pneumonia

Anesthesiology

Published on 2021-11-162022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] 24 hour acute respiratory distress syndrome [ards] airway intubation Analysis analyzed baseline characteristics benefit Comorbidities coronavirus disease COVID-19 covid-19 respiratory failure Critically ill patient death deteriorate Detroit discharge distress Effect group groups healthcare providers Henry Ford High flow nasal canula higher risk hospital Hospital admission intensive care Intubated intubation Kaplan-Meier Kaplan-Meier survival curves mechanical ventilation Mortality nasal Observational cohort study observé organ dysfunction Organ failure outcome outcomes overall mortality Oxygenation pandemic Patient patients with COVID-19 performed Pneumonia post-hoc analysis Primary outcome question raised reduced risk respiratory respiratory rate Result Resuscitation retrospective risk ROX ROX index secondary secondary to Severe COVID-19 pneumonia Severe respiratory distress severe respiratory failure severe respiratory illness Significant significant difference significantly significantly higher significantly lower significantly more single-center SOFA SOFA score statistically significant difference subgroup of patient survival the timing therapy treated Treatment Ventilation while
[DOI] 10.7759/cureus.19620 PMC 바로가기 [Article Type] Anesthesiology

Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases

Article

Published on 2021-11-012022-10-04
Journal: Acta pharmacologica Sinica [Category] SARS, 신약개발,

[키워드] activating activity addition alcohol anti-inflammatory activity applied cause caused Cellular responses circulating Colitis Complication contribute disulfiram DSF dysregulated immune response effective Efficacy endotoxin gasdermin D glycoprotein immunosuppressive Infection Inflammation Inflammatory cytokine inflammatory disease inflammatory disorders Inflammatory response inhibitor lactoferrin life-threatening ligands Macrophage macrophage-targeting delivery macrophages multifunctional murine Neutralizing offer organ dysfunction patients pyroptosis Safe Sepsis therapeutic therapeutic effect therapeutic strategy treat Treatment ulcerative colitis various inflammatory disease
[DOI] 10.1038/s41401-021-00770-w PMC 바로가기 [Article Type] Article

High flow nasal cannula for adult acute hypoxemic respiratory failure in the ED setting

응급실 환경에서 성인 급성 저산소성 호흡 부전을 위한 고유량 비강 캐뉼러

Review

Published on 2021-11-012022-09-11
Journal: The American journal of emergency medicine [Category] SARS, 임상,

[키워드] Acute hypoxemic respiratory failure acute respiratory distress acute respiratory distress syndrome Adult patients airway airway resistance anatomical anatomical dead space Appropriate ARDS asynchrony condition conditions Control coronavirus disease Coronavirus disease 2019 COVID-19 dead Dead space demonstrated Efficacy emergency department end organ evaluate expiratory Expiratory Pressure Factor flush foundation fraction hand hygiene healthcare personnel HFNC High flow nasal cannula High-flow nasal cannula hygiene hypoxemic Hypoxemic respiratory failure Immunocompromised IMPROVE in some increased risk individual infection control Interstitial lung disease Intervention intubation Lung disease Mortality nasal nasal cannula NIV Noninvasive ventilation organ dysfunction oxygen Oxygenation Palliative care Patient patients with COVID-19 Personal protective equipment Pneumonia poor oxygenation positive Positive End Expiratory Pressure promise provide randomized trial recent reduce reduced Relative humidity respiratory distress Respiratory failure respiratory rate Respiratory Support risk significantly increased surgical syndrome Tachycardia the patient utility Ventilation warm
[DOI] 10.1016/j.ajem.2021.06.074 PMC 바로가기 [Article Type] Review

Ultramicronized Palmitoylethanolamide in the Management of Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation

Article

Published on 2021-10-212022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS,

COVID-PIRO (Predisposition, Insult, Response, Organ Dysfunction) Score: A Reliable Predictor of Outcomes in COVID-19 Patients Admitted in Intensive Care Unit

Internal Medicine

Published on 2021-10-212022-10-31
Journal: Cureus [Category] COVID-19,

Signaling pathways in the regulation of cytokine release syndrome in human diseases and intervention therapy

Review Article

Published on 2021-10-202022-10-04
Journal: Signal Transduction and Targeted Therapy [Category] MERS, SARS, 바이오마커, 치료제,

[키워드] adverse event Allogeneic Autoimmune diseases CAR-T Characteristics characterized chimeric antigen receptor circulating clinical feature clinical manifestations clinically COVID-19 CRS cytokine cytokine levels Cytokine release syndrome described disease disorder Efficacy elevated feature Fever Host human disease hyperinflammation Immunological disorders Immunotherapy incidence Infectious diseases Influenza Intervention life-threatening management mechanism organ dysfunction Pandemics pathway potential mechanism Regulation SARS-CoV signaling pathways Symptom syndrome systemic inflammatory therapy Toxicity
[DOI] 10.1038/s41392-021-00764-4 PMC 바로가기 [Article Type] Review Article

Research Progress in Chinese Herbal Medicines for Treatment of Sepsis: Pharmacological Action, Phytochemistry, and Pharmacokinetics

Review

Published on 2021-10-142022-10-29
Journal: International Journal of Molecular Sciences [Category] Coronavirus, MERS, SARS,

Removal of COVID-19 Spike Protein, Whole Virus, Exosomes, and Exosomal MicroRNAs by the Hemopurifier® Lectin-Affinity Cartridge in Critically Ill Patients With COVID-19 Infection

Medicine

Published on 2021-10-082022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,