organoids
[대역어] 장관_오가노이드
[용어속성] Term
[용어속성] Term
Human Brain Organoids as an In Vitro Model System of Viral Infectious Diseases
Immunology
[키워드] Brain
brain organoid
brainoid
Central nervous system
CNS
help
HIV
HSV-1
Human
Human immunodeficiency virus
Infection
Infectious disease
limitation
mechanism
microcephaly
Model
model system
modeling
organ
Organoid
organoids
Pathogenesis
pathogenesis of SARS-CoV-2
prion
shown
System
viral infection
virus
Zika virus
ZIKV
[DOI] 10.3389/fimmu.2021.792316 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2021.792316 PMC 바로가기 [Article Type] Immunology
Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations
신장 오르가노이드 및 임상 인구에서 SARS-CoV-2 반응의 교차 검증
Research Article
[키워드] Alpha
ameliorated
Apoptosis
Beta
blocked
Cell
cell types
Clinical data
comparable
COVID-19
Critical
Critically ill
Critically ill patient
critically ill patients
Cross-validation
feature
gene expression pattern
gene expression patterns
Genetic diseases
infect
Infection
interferon
interferon pathway
iPS cells
Kidney disease
kidney infection
kidney organoid
kidneys
mechanism
Molecular pathology
morphology
Nephrology
organ
Organoid
organoids
peptides
polycystic kidney
polycystic kidney disease
Population
populations
proteomic
proximal
proximal tubules
reflect
reflected
replicating virus
response
SARS-CoV-2
SARS-CoV-2 variant
SARS-CoV-2 variants
SARS-CoV-2 viral
susceptibility
target organs
Therapeutics
Therapies
Treatment
tropism
upregulation
Urine
variant
Viral
viral fitness
[DOI] 10.1172/jci.insight.154882 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1172/jci.insight.154882 PMC 바로가기 [Article Type] Research Article
COVID-19 and gut immunomodulation
코로나19와 장 면역 조절
Review
[키워드] acute respiratory syndrome
Adaptive immune response
addition
angiotensin-converting enzyme-2
antibodies
association
calprotectin
changes in
clinically
Comorbidities
coronavirus
coronavirus disease
COVID-19
COVID-19 patient
COVID-19 patients
Cytokines
dependent on
direct infection
disease
disease severity
Dysbiosis
epithelial cell
expresse
Gastrointestinal
gastrointestinal symptoms
GI symptom
GI symptoms
GI Tract
Gut
gut microbiota
Health
heterogeneous
hypoxia
immune
immune activation
immune response
Immunity
immunoglobulin A
impairment
in vitro
in vivo
infect
infected individual
Infection
Innate
innate immune response
intestinal epithelium
observation
organ
organoids
outcome
Pathogenesis
Patient
positive
Pre-existing diseases
Probiotic
Proinflammatory cytokine
protease
Protein
reported
required
respiratory problems
respiratory symptom
Respiratory system
rhesus
SARS-CoV-2
serine 2
severe COVID-19 patient
severe respiratory illness
severity
Stool
supported
Symptom
symptomatic patient
the disease
therapeutic interventions
Therapeutics
transmembrane
Viral RNA
virus
[DOI] 10.3748/wjg.v27.i46.7925 PMC 바로가기 [Article Type] Review
[DOI] 10.3748/wjg.v27.i46.7925 PMC 바로가기 [Article Type] Review
Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections
Article
[키워드] acute respiratory syndrome
Affect
Analysis
Antiviral
antiviral drug combination
antiviral property
Calu-3 cell
changes in
clinical development
Combination
concentrations
convalescent serum
coronavirus
cycloheximide
demonstrated
drug
effective
EIDD-2801
HCV
hepatitis C virus
hepatitis E virus
HIV
homeostasis
Human immunodeficiency virus
IFN
IFNs
IFNα
in vitro
indicated
influenza A virus
interferon
interferon-alpha
lung organoids
metabolomic
NITD008
organoids
Other
protein synthesis
Remdesivir
Replication
ribavirin
SARS-CoV-2
Side effects
suppressed
synergistic
target
tested
therapeutic potential
tolerable
Transcription
uninfected cell
viral infections
Viral RNA
while
[DOI] 10.3390/v13122489 PMC 바로가기 [Article Type] Article
[DOI] 10.3390/v13122489 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infection and replication in human gastric organoids
인간 위 오르가노이드에서의 SARS-CoV-2 감염 및 복제
Article
[키워드] adult stem cells
antiviral response
biopsy
children
COVID-19
described
differentially expressed gene
Differentially expressed genes
differentiation
facilitate
fetal
Gastrointestinal models
Gastrointestinal symptom
gastrointestinal symptoms
generate
in vitro model
induce
infect
Infection
infection with SARS-CoV-2
lack
moderate
observation
Organoid
organoids
pediatric
question
raise
replicate
Replication
Respiratory illness
Respiratory system
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 transmission
significantly lower
stomach
susceptible
the interferon
transcriptomic analysis
Transmission
viral clearance
viral infection
viral replication
viral shedding
virus
[DOI] 10.1038/s41467-021-26762-2 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41467-021-26762-2 PMC 바로가기 [Article Type] Article
Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets
remdesivir 부모 GS-441524의 경구 전구 약물은 흰 족제비에서 SARS-COV-2에 대해 효과적입니다.
Article
[키워드] Administered
administration
animal model
anti-SARS-CoV-2
Antiviral
Antiviral treatment
antivirals
approved
block
boost
Cell culture
Contact
COVID-19
COVID-19 treatment
dosed
early administration
Efficacy
ferret
ferrets
GS-441524
Human airway epithelium
inhibit
inhibit SARS-CoV-2
intravenous
intravenously
lung
Lungs
mechanism
metabolite
nucleoside
oral
oral administration
oral bioavailability
organoids
parent nucleoside
patients
plasma
Prevent
prodrug
reduce
Remdesivir
SARS-CoV-2
SARS-COV-2 infection
Therapeutic benefit
therapeutic efficacy
Transmission
Treatment
triphosphate
variants
variants of concern
virus replication
VoC
[DOI] 10.1038/s41467-021-26760-4 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41467-021-26760-4 PMC 바로가기 [Article Type] Article
COVID-19 Mechanisms in the Human Body—What We Know So Far
인체의 COVID-19 메커니즘 - 우리가 지금까지 알고 있는 것
Review
[키워드] accumulated
acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
addressed
animal models
being
caused
Cell
Cell culture
changed
complications
conducted
consequence
coronavirus
coronavirus disease
Coronavirus disease 2019
COVID-19
dysregulations
elapsed
Evidence
experiments
extreme
globe
greater
greater transmissibility
Health
Human
human body
human immune response
Immune escape
immune response
immunological dysregulations
Infection
initial
knowledge
measure
mechanism
mechanisms
molecular mechanism
molecular mechanisms
organ-specific
organoids
organotropism
pandemic
Pathogenesis
pathogenic mechanisms
physiological systems
respiratory
SARS-CoV-2
SARS-CoV-2 variants
scenario
Survivors
systemic manifestations
the disease
therapeutic
tissue
tissue tropism
type strain
variant
Viral
virulence
virus
virus–host interactions
wild-type strain
[DOI] 10.3389/fimmu.2021.693938 PMC 바로가기 [Article Type] Review
[DOI] 10.3389/fimmu.2021.693938 PMC 바로가기 [Article Type] Review
Direct SARS-CoV-2 infection of the human inner ear may underlie COVID-19-associated audiovestibular dysfunction
Article
[키워드] ACE2
angiotensin-converting enzyme 2
caused
Cell
cell types
cellular
cofactor
confocal microscopy
Coronavirus disease 2019
COVID-19
COVID-19 patient
demonstrated
Direct
disease
Dizziness
dysfunction
Express
expression
hearing loss
in vitro
in vitro model
infect
Infection
infection rate
Infectious disease
molecular
molecular mechanism
novel coronavirus SARS-CoV-2
Organoid
organoids
pandemic
patients with COVID-19
pluripotent stem cells
precursor
problem
protease
receptor
required
Result
SARS-CoV-2
SARS-CoV-2 entry
SARS-CoV-2 entry factors
SARS-COV-2 infection
SARS-CoV-2 virus
Schwann cell
serine 2
stem cells
susceptible
Symptom
Symptoms
target
these symptoms
tissue
tissues
TMPRSS2
transmembrane
two-dimensional
underlie
vascular disease
Virology
virus entry
with COVID-19
[DOI] 10.1038/s43856-021-00044-w PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s43856-021-00044-w PMC 바로가기 [Article Type] Article
Recent Advances of COVID-19 Modeling Based on Regenerative Medicine
Cell and Developmental Biology
[키워드] 3D structure
advance
angiotensin-converting enzyme 2
animal models
catch
caused
cell line
cell population
COVID-19
deficiency
drug
drugs
Endocrine
future therapeutic
Health
Health Organization
host cell
induced pluripotent stem cells
Infection
introduced
involved
liver
main receptor
mechanism
Medicine
mice
Model
modeling
neurologic
offer
Organoid
organoids
other organ
pandemic
pathogenicity
pathophysiology
pluripotent stem cell
recent
receptors
regenerative
regenerative medicine
renal systems
respiratory
respiratory infection
responsible
SARS-CoV-2
SARS-COV-2 infection
stem cell
subjects
suggested
treat
Vaccine
virus
Wuhan, China
[DOI] 10.3389/fcell.2021.683619 PMC 바로가기 [Article Type] Cell and Developmental Biology
[DOI] 10.3389/fcell.2021.683619 PMC 바로가기 [Article Type] Cell and Developmental Biology