The Occurrence of Alzheimer’s Disease and Parkinson’s Disease in Individuals With Osteoporosis: A Longitudinal Follow-Up Study Using a National Health Screening Database in Koreaarticle Published on 2021-12-082024-09-02 Journal: Frontiers in Aging Neuroscience [Category] 대상포진, [키워드] Alzheimer’s disease longitudinal follow-up study nationwide population-based cohort study Osteoporosis Parkinson’s disease [DOI] 10.3389/fnagi.2021.786337 PMC 바로가기 [Article Type] article
Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era전문 요양 시설에서 COVID-19에 대한 Fisetin: COVID 시대의 세놀리틱 시험Article Published on 2021-11-012022-09-11 Journal: Journal of the American Geriatrics Society [Category] MERS, 비임상, 임상, 진단, [키워드] administration Adults alleviate amplified animal model animal models Apoptosis biospecimen biospecimens breath cardiovascular Care cellular cellular senescence Chronic diseases Clinical data clinical trial clinical trials Complication condition COVID COVID-19 cytokine Cytokine storm death decrease diabetes disorder facility facility for geroscience analysis Factor Factors Fisetin frailty Hospitalized include individual kidney Logistic Long-term care Lung diseases mechanism morbidity morbidity and mortality multicenter multiorgan failure National obesity Older older adult Older adults Osteoporosis pathogen pathogen-associated molecular patients phenotype Placebo placebo-controlled clinical trial Prevent produced progression rationale respiratory respiratory diseases risk risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection SASP senescent cell senescent cells Senolytic senolytics. skilled nursing facility the SARS-CoV-2 Translational Geroscience Network Trial [DOI] 10.1111/jgs.17416 PMC 바로가기 [Article Type] Article
Linarin, a Glycosylated Flavonoid, with Potential Therapeutic Attributes: A Comprehensive ReviewReview Published on 2021-10-292022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] acetylcholinesterase activity assessment bioactivities Biological biological properties Buddleja Central nervous system Characteristics characterized chemotaxonomy Cirsium CNS compounds Comprehensive derivatives dietary supplement disorders drug candidates Effect exhibited flavonoid flavonoids Health indicated inhibitory activity linarin Osteoarthritis Osteoporosis pharmacological phytochemistry Potential proliferation review therapeutic [DOI] 10.3390/ph14111104 PMC 바로가기 [Article Type] Review
Exact sequential test for clinical trials and post-market drug and vaccine safety surveillance with Poisson and binary dataPoisson 및 Binary Data를 사용한 임상 시험 및 시장 후 약물 및 백신 안전 감시에 대한 정확한 순차적 테스트Article Published on 2021-09-302022-08-31 Journal: Statistics in medicine [Category] MERS, SARS, 치료제, [키워드] adaptive adaptive design addition adverse event adverse events Alpha alpha spending Analysis calculation clinical trial continuous monitoring COVID-19 pandemic decision develop effort example expected group sequential. Hypothesis Hypothesis testing Influenza influenza vaccination Osteoporosis package performed Poisson R language Sample size sample sizes sequential analysis sequential test Signaling Statistical power Surveillance threshold Treatment vaccination Vaccine [DOI] 10.1002/sim.9094 PMC 바로가기 [Article Type] Article
Emerging therapeutic opportunities for integrin inhibitors Reviews Published on 2021-09-172022-10-05 Journal: Nature Reviews Drug Discovery [Category] 바이오마커, [키워드] Biological functions bowel Cancer cardiovascular diseases Cell clinical development clinical trials clinically disease Diseases drug Drug discovery Inflammatory inhibitor integrin Integrins investigated New Osteoporosis pharmacological Protein pulmonary fibrosis Research review steatohepatitis therapeutic Treatment [DOI] 10.1038/s41573-021-00284-4 [Article Type] Reviews
Vitamin D and Platelets: A Menacing Duo in COVID-19 and Potential Relation to Bone RemodelingReview Published on 2021-09-162022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] Activation aggregation altered bone remodeling association bone characterized Coagulation Coagulopathy complications COVID-19 COVID-19 infection deficiency Endothelial dysfunction Factor Health Health status hypercoagulable immune response increase Inflammation information lung mineral metabolism Osteoporosis other organs parameter pathological conditions Platelet Platelets Potential promote relation remodeling severe COVID-19 patient severe COVID-19 patients stimulate thrombosis Vitamin D [DOI] 10.3390/ijms221810010 PMC 바로가기 [Article Type] Review
Blood factors as biomarkers in osteoporosis: points from the COVID-19 era골다공증에서 바이오 마커로서의 혈액 요인 : Covid-19 시대의 점수Review Published on 2021-09-012022-08-31 Journal: Trends in endocrinology and metabolism: TEM [Category] 바이오마커, 진단, [키워드] adopted Biomarker Biomarkers both sexes Chronic diseases clinically complications coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic detect diagnostic effective Factor Factors Health healthcare identify MONITOR monocyte Osteoporosis pandemic Participation Patient Platelet Platelets Population provide reduced risk spontaneous osteoclastogenesis. stability [DOI] 10.1016/j.tem.2021.05.005 PMC 바로가기 [Article Type] Review
Medical Comorbidities and Complications Associated with Poliomyelitis and Its Sequelaearticle Published on 2021-08-312024-09-01 Journal: Physical medicine and rehabilitation clinics of North America [Category] 폴리오, [키워드] Cardiovascular deconditioning Comorbidity Osteoporosis poliomyelitis Postpoliomyelitis syndrome [Article Type] article
The Use of Oral Amino‐Bisphosphonates and Coronavirus Disease 2019 ( COVID ‐19) OutcomesObservational Study Published on 2021-08-222022-10-04 Journal: Journal of Bone and Mineral Research [Category] MERS, SARS, 임상, [키워드] 95% CI 95% confidence interval alendronate Analysis analyzed ATC Bisphosphonates bone Cancer Cardiovascular events classification clinical Cohort conducted COVID COVID‐19 COVID‐19 infection COVID‐19 death determinant drugs excluded Glucocorticoid treatment Hospitalization Hypothesis ICU incidence Infection infection risk intensive care Italian population journal LLC manifestation mineral Mortality Ninth Observational cohort study oral Osteoporosis Patient Periodical prevalent Prevent reduce respiratory infections retrospective revision risk SARS‐CoV‐2 SARS‐CoV‐2 severe coronavirus disease shown Society subjects Support susceptibility Treatment [DOI] 10.1002/jbmr.4419 PMC 바로가기 [Article Type] Observational Study
Health and Gender Inequalities of the COVID-19 Pandemic: Adverse Impacts on Women’s Health, Wealth and Social WelfareGlobal Women's Health Published on 2021-07-202022-10-31 Journal: Frontiers in Global Women's Health [Category] COVID-19, [키워드] adopted Adverse adverse impact affected Care carried chronic disease Comorbidities COVID-19 COVID-19 pandemic demonstrated detrimental develop disease Diseases engage expected Gender global health Health highlight Impact increasingly independent individual inequality manifested men Musculoskeletal ontological Osteoarthritis Osteoporosis outcome outcomes pandemic public health public health measure Research rheumatoid arthritis SLE Spread structures systemic lupus erythematosus Systemic sclerosis Welfare women women's health [DOI] 10.3389/fgwh.2021.670310 PMC 바로가기 [Article Type] Global Women's Health