Interaction between host genes and Mycobacterium tuberculosis lineage can affect tuberculosis severity: Evidence for coevolution?숙주 유전자와 Mycobacterium tuberculosis 계통 간의 상호 작용은 결핵 중증도에 영향을 줄 수 있습니다. 공진화의 증거?Research Article Published on 2020-04-302022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addition Affect affected allele alleles animal model animal models association co-occurrence Cohort Combination Contact disease risk disease severity DNA examined explain explained Genetic studies Genetic variation genetics Genome genomes Genotype Host host gene Human human allele Human genetics human host Hypothesis IL12B increased risk independent Infectious disease Infectious diseases Interaction Lineage modulate Mycobacterium tuberculosis nucleotide other infectious diseases patient cohort polymorphism promote reduce replicated risk severe disease severity Severity of disease significant interaction single nucleotide Single nucleotide polymorphism SLC11A1 SNP SNPs susceptibility tested Tuberculosis Uganda unit Variation [DOI] 10.1371/journal.pgen.1008728 PMC 바로가기 [Article Type] Research Article
First two months of the 2019 Coronavirus Disease (COVID-19) epidemic in China: real-time surveillance and evaluation with a second derivative model중국의 2019 코로나바이러스 질병(COVID-19) 전염병의 첫 두 달: 2차 파생 모델을 통한 실시간 감시 및 평가Research Published on 2020-03-022022-09-10 Journal: Global Health Research and Policy [Category] MERS, SARS, 치료기술, [키워드] 2019-nCoV, outbreak accelerated analyses Analysis assumption China clinician Collaborative effort coronavirus coronavirus epidemic Coronavirus infection COVID-19 detectable detection rate diagnosed Diseases Dynamic modeling effective interventions Epidemic increase indicated infections Infectious disease epidemic Infectious diseases information initiated Intervention occurred other infectious diseases outbreak professionals public health Result Second derivative study period Surveillance the epidemic [DOI] 10.1186/s41256-020-00137-4 PMC 바로가기 [Article Type] Research
A novel framework for inferring parameters of transmission from viral sequence data바이러스 염기서열 데이터로부터 전파 매개변수를 추론하기 위한 새로운 프레임워크Research Article Published on 2018-10-162022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affect alleles Applying approach approaches baseline collected Critical determine Diseases evaluate event events example extension Genetic genetic diversity Genetic variant genetic variants Genome sequence data Host hosts identify independent Infection infections Infectious diseases Inference Influenza Influenza virus inherent Interpretation lifecycle new infection new infections occur other infectious diseases parameter Particle Particles pathogen Pathogens population bottleneck Population genetics provide Quantitative recent sequence Spread statistical analysis Transmissibility Transmission transmitted Viral Viral transmission virulence viruses [DOI] 10.1371/journal.pgen.1007718 PMC 바로가기 [Article Type] Research Article