The predicting roles of carcinoembryonic antigen and its underlying mechanism in the progression of coronavirus disease 2019Carcinoembryonic 항원의 예측 역할과 코로나 바이러스 질병의 진행에서의 기본 메커니즘 2019Research Published on 2021-07-032022-08-31 Journal: Critical Care [Category] SARS, 바이오마커, [키워드] adult COVID-19 patient Analysis Antigen BALF Biomarker Carcinoembryonic antigen Carcinoembryonic antigen-related cell adhesion molecules CEA CEACAM6 CEACAM8 conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients Developing neutrophils downloaded epidemiological Hospitalized identify Laboratory lung Lungs mechanism Mortality Multivariate analysis neutrophil Neutrophils objective overall survival PBMC PBMCs potential mechanism predict predictor prognostic prognostic indicator Prognostic value progression Result Retrospective study scRNA-seq data significant difference significantly supplementary material survival Type II pneumocyte type II pneumocytes Wuhan [DOI] 10.1186/s13054-021-03661-y PMC 바로가기 [Article Type] Research
COVID-19 and stem cell transplantation; results from an EBMT and GETH multicenter prospective surveyArticle Published on 2021-06-022022-10-30 Journal: Leukemia [Category] COVID-19, MERS, SARS, [키워드] Admission Allogeneic Analysis autologous Cell cell transplantation COVID-19 COVID-19 patient Diagnosis disease European Factor group GVHD haematological diseases HCT hematopoietic high risk ICU immunodeficiency Immunosuppression increased mortality increased the risk Infectious diseases Lower respiratory tract Marrow median age median time Mortality multicenter Older age Other overall survival Patient patients performance status recipients reported risk significantly Society Spanish STEM survival transplantation [DOI] 10.1038/s41375-021-01302-5 PMC 바로가기 [Article Type] Article
Future Directions in Maintenance Therapy in Multiple MyelomaReview Published on 2021-05-242024-09-02 Journal: Journal of Clinical Medicine [Category] 대상포진, [키워드] lenalidomide maintenance Minimal residual disease Multiple myeloma overall survival Transplant [DOI] 10.3390/jcm10112261 PMC 바로가기 [Article Type] Review
Downregulation of ACE2 expression by SARS-CoV-2 worsens the prognosis of KIRC and KIRP patients via metabolism and immunoregulationResearch Paper Published on 2021-05-102022-10-29 Journal: International Journal of Biological Sciences [Category] COVID-19, SARS, [키워드] Accuracy ACE2 ACE2 expression acute respiratory syndrome animal model Atla bioinformatics Cancer Cancer patients Cancer therapy Cell clinical information clinical risk coronavirus correlated correlation database diagnosing downregulated downregulation enzyme exhibit expression function Gene Expression Gene Expression Omnibus GEO high risk host cell human tissues immune immune infiltration immunoregulation involved kidney metabolic pathway metabolism not correlated overall survival overlap Patient patient survival patients Predictive Prognosis renal Renal cancer SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected cell searched significantly survival Symptoms target tissue TMPRSS2 transmembrane serine protease upregulated Xena [DOI] 10.7150/ijbs.57802 PMC 바로가기 [Article Type] Research Paper
Relationship between Tertiary Lymphoid Structure and the Prognosis and Clinicopathologic Characteristics in Solid TumorsResearch Paper Published on 2021-04-072023-08-30 Journal: International Journal of Medical Sciences [Category] E형 간염, [키워드] clinicopathologic characteristics. Disease-free survival overall survival relapse-free survival tertiary lymphoid structure (TLS) Tumor [DOI] 10.7150/ijms.56347 PMC 바로가기 [Article Type] Research Paper
Clinical Efficacy of Hydroxychloroquine in Patients with COVID-19: Findings from an Observational Comparative Study in Saudi ArabiaArticle Published on 2021-03-312022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] according to protocol Admission Antiviral Baha Care carried clinical clinical effectiveness Comparative comparative observational study control group coronavirus disease COVID-19 dose duration of hospitalization Evidence finding groups HCQ hospital Hospital stay Hydroxychloroquine ICU IMPROVE intensive care mechanical ventilation Ministry of Health Mortality mortality rates no significant difference not reduce overall survival Patient patients hospitalized patients with COVID-19 Primary outcome provide receive regimen Saudi Arabia standard treatment treated Treatment treatment group with COVID-19 [DOI] 10.3390/antibiotics10040365 PMC 바로가기 [Article Type] Article
Assessment of Simulated SARS-CoV-2 Infection and Mortality Risk Associated With Radiation Therapy Among Patients in 8 Randomized Clinical Trials8건의 무작위 임상 시험에서 시뮬레이션된 SARS-CoV-2 감염 및 방사선 요법과 관련된 사망 위험 평가Research Published on 2021-03-292022-09-10 Journal: JAMA Network Open [Category] 임상, [키워드] accelerated analyzed approach assessment benefit Breast cancer Cancer Cancer therapy Care Case fatality rate case fatality rates CFR CFRs changes in clinical clinical trial clinical trials COVID-19 COVID-19 pandemic Cox proportional hazard Cox proportional hazards decreased mortality early stage Effectiveness Estimated evaluated expected exposure Factor fast finding flexible fraction fractionation Fractions higher risk hypo Impact Importance Inclusion infection risk IRF IRFs Kaplan-Meier Local measure median moderate Modification Mortality mortality rates objective oncology outcome outcomes overall survival pandemic participant Patient patients Point Precaution Prostate cancer provide Quantitative quantitative framework Radiation radiation therapy randomized clinical trial randomized trial randomized trials receipt receiving rectal rectal cancer reducing regimens Relevance Result risk SARS-CoV-2 SARS-COV-2 infection scenario setting significantly Support survival Treatment treatment arm Trial [DOI] 10.1001/jamanetworkopen.2021.3304 PMC 바로가기 [Article Type] Research
A retrospective analysis of pembrolizumab plus chemotherapy versus pembrolizumab monotherapy for advanced or recurrent non‐small cell lung cancerOriginal Article Published on 2021-03-122024-09-02 Journal: Thoracic Cancer [Category] 대상포진, [키워드] adverse event combination therapy Immune checkpoint inhibitor overall survival treatment discontinuation [DOI] 10.1111/1759-7714.13915 PMC 바로가기 [Article Type] Original Article
Early Administration of Convalescent Plasma Improves Survival in Patients with Hematological Malignancies and COVID-19Brief Report Published on 2021-03-082022-10-28 Journal: Viruses [Category] COVID-19, [키워드] analyzed characterized Clinical improvement Cohort cohort of patient convalescent plasma Course COVID-19 demonstrated Determining Diagnosis early administration effective Efficacy faster Hematological malignancies Hematological malignancy high risk Infection knowledge less outcomes overall survival Patient plasma Population severe symptom significantly significantly higher survival therapy Treatment viral clearance [DOI] 10.3390/v13030436 PMC 바로가기 [Article Type] Brief Report
Uncertainty in the impact of liver support systems in acute-on-chronic liver failure: a systematic review and network meta-analysisReview Published on 2021-01-182023-08-29 Journal: Annals of Intensive Care [Category] E형 간염, [키워드] BioLogic-DT ELAD Liver support therapy MARS Network meta-analysis overall survival plasma exchange Prometheus SUCRA Transplant-free survival [DOI] 10.1186/s13613-020-00795-0 PMC 바로가기 [Article Type] Review