passive immunity – Page 4 – Communicable Diseases Research

Human Milk Antibodies after BNT162b2 Vaccination Exhibit Reduced Binding against SARS-CoV-2 Variants of Concern

Article

Published on 2022-01-312022-10-28
Journal: Vaccines [Category] COVID-19,

Milk From Women Diagnosed With COVID-19 Does Not Contain SARS-CoV-2 RNA but Has Persistent Levels of SARS-CoV-2-Specific IgA Antibodies

Immunology

Published on 2021-12-232022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, SARS,

[키워드] 95% CI acute respiratory syndrome analyzed anti-RBD IgA antibodies benefit Breastfeeding collected Concentration coronavirus coronavirus disease coughing COVID-19 COVID-19 illness COVID-19 symptom detection Diagnosis diagnostic human milk IgA Immunoglobulin immunoglobulins Infection lactating women Level Limited milk MOST objective onset of symptom passive immunity persistent positive Positive test produced RBD Receptor binding domain recommendation Result risk SARS-CoV-2 SARS-CoV-2 RNA Seven spike glycoprotein Study design Support Swab swabs tested the SARS-CoV-2 was tested with COVID-19 women
[DOI] 10.3389/fimmu.2021.801797 PMC 바로가기 [Article Type] Immunology

Safety and Seroconversion of Immunotherapies against SARS-CoV-2 Infection: A Systematic Review and Meta-Analysis of Clinical Trials

Systematic Review

Published on 2021-11-242022-10-28
Journal: Pathogens [Category] COVID-19,

[키워드] 95% CI active immunity acute respiratory syndrome adverse event AEs Analysis Antibody Response clinical clinical trial clinical trials components conducted Controlled Coronavirus disease 2019 (COVID-19) Coronavirus-2 defined Efficacy enrolled evaluate healthy Heterologous heterologous immunity host immunity immune response Immunity immunological Immunotherapy inactivated Infection injected inoculated Intervention involved mechanism meta-analyses Meta-analysis neutralize Odds ratio participant passive immunity populations pre-vaccination Prophylactic Protein random-effect Registered review RNA Safety SARS-CoV-2 searched sera Seroconversion severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) systemic adverse event systemic AE therapeutic Treatment Trial trials vaccination Vaccine Vaccines Viral vector viral vector-based virus was used
[DOI] 10.3390/pathogens10121537 PMC 바로가기 [Article Type] Systematic Review

Immune Response of Neonates Born to Mothers Infected With SARS-CoV-2

SARS-CoV-2에 감염된 산모에게서 태어난 신생아의 면역 반응

Observational Study

Published on 2021-11-032022-09-10
Journal: JAMA Network Open [Category] MERS, SARS, 임상, 진단, 치료기술,

[키워드] 48 hour 48 hours age antibody antibody production arbitrary unit association Birth breastmilk children Clinical outcome cohort study enrolled enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated explain exposure exposure to finding Follow-up gestational age IgA IgA antibodies IgA antibody IgG antibodies IgM antibodies IgM antibody immune complex Immune complexes immune response immune responses immune system Importance in utero Infant Infants infected with SARS-CoV-2 Infection infection with SARS-CoV-2 information investigated IQR Italy life male Maternal maternal age measure mother mucosal mucosal immune Neonatal Neonate Newborn objective occurred offspring participant parturition passive immunity Point positive Pregnancy pregnant women prospective cohort study PROTECT provided Receptor binding Receptor binding domain Relevance response Result Rome Saliva salivary SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 spike secretory IgA serum setting significantly higher significantly increased specific antibodies specific antibody specific IgG antibodies spike-specific antibodies Spike-specific antibody spike-specific IgG stimulate systemic immune response systemic immune responses tested transfer Transmission Umberto vertical transmission vertical virus transmission virus Virus spike virus transmission
[DOI] 10.1001/jamanetworkopen.2021.32563 PMC 바로가기 [Article Type] Observational Study

Timing of SARS-CoV-2 vaccination during the third trimester of pregnancy and transplacental antibody transfer: a prospective cohort study

Original Article

Published on 2021-11-032022-10-04
Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 진단,

[키워드] acute respiratory syndrome Administered age Antenatal anti-S antibody antibody transfer Blood collected Concentration Cord blood coronavirus Coronavirus disease 2019 domain ENhance evaluated first dose gestation greater highlight IgG IgG level immunization immunized interquartile range IQR Maternal median mRNA vaccination Neonatal Neutralizing neutralizing antibody objective passive immunity placental positive positively correlated Pregnancy pregnant women prospective cohort study RBD Result SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 BNT162b2 SARS-CoV-2 spike protein SARS-CoV-2 vaccination sera serology severe acute respiratory syndrome coronavirus 2 study cohort transfer vaccination vaccine dose
[DOI] 10.1016/j.cmi.2021.10.003 PMC 바로가기 [Article Type] Original Article

COVID-19 mRNA Vaccination in Lactation: Assessment of Adverse Events and Vaccine Related Antibodies in Mother-Infant Dyads

수유에서의 Covid-19 mRNA 백신 접종 : 마시어-영향 다이어드에서의 부작용 및 백신 관련 항체의 평가

Immunology

Published on 2021-11-032022-08-13
Journal: Frontiers in Immunology [Category] MERS, SARS, 임상,

[키워드] addition Adverse adverse event age anti-RBD anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies antibodies antibody assessment automated Blood blood sample Blood samples BNT162b2 Breastfeeding Cohort collected COVID-19 COVID-19 mRNA Vaccination COVID-19 mRNA vaccine diagnosed with COVID-19 dose dyad ELISA first vaccination generate human milk IgA IgA level IgG antibodies IgG antibody IgM immune response immune responses immunoassay individual Infant Infants lactating lactation maternal plasma milk mother mRNA mRNA vaccine mRNA vaccines mRNA-1273 mRNA-based vaccine mRNA-based vaccines passive immunity PEGylated protein PEGylated proteins plasma prospective cohort Pylon 3D Questionnaires reported Result robust SARS-CoV-2 severe adverse event severe adverse events significant level significantly increased study period subset Symptom the vaccine transfer vaccination were assessed were measured
[DOI] 10.3389/fimmu.2021.777103 PMC 바로가기 [Article Type] Immunology

Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19

경증 또는 중등도의 Covid-19에서 밤라니비맙과 에테세비맙

Clinical Trial

Published on 2021-10-072022-09-12
Journal: The New England Journal of Medicine [Category] MERS, SARS, 신약개발, 임상, 진단,

[키워드] 1:1 95% CI 95% confidence interval accelerated acute respiratory syndrome Administered age ambulatory patient ambulatory patients assigned bamlanivimab baseline clinical status Cohort Combination complications coronavirus death defined develop Diagnosis Disease progression etesevimab greater high risk Hospitalization Immunity incidence increased risk Infection investigator Laboratory limit log medical condition Mild moderate NCT04427501 Neutralizing occurred passive immunity Patient patients phase 3 trial Placebo Primary outcome progression provide randomization Randomly receive reduction risk SARS-CoV-2 severe coronavirus disease severe disease single intravenous infusion the patient the placebo group the SARS-CoV-2 Treatment Trial Viral load women
[DOI] 10.1056/NEJMoa2102685 PMC 바로가기 [Article Type] Clinical Trial

Immunological assessment of SARS-CoV-2 infection in pregnancy from diagnosis to delivery: A multicentre prospective study

진단에서 전달까지 임신 중 SARS-COV-2 감염의 면역 학적 평가 : 다기관 전향 연구

Observational Study

Published on 2021-09-202022-09-10
Journal: PLoS ONE [Category] MERS, SARS, 임상, 진단, 치료기술,

[키워드] 95% CI Abbott Abbott SARS-CoV-2 IgG All participants Antenatal anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody antibody Antibody Response Antibody responses Architect Asymptomatic baseline Blood Cohort Combination conducted Cord blood demonstrated detectable Diagnosis Elecsys Europe evidence of fetal FIVE gestation hospital IgG IgG antibodies IgG SARS-CoV-2 antibodies IgG SARS-CoV-2 antibody IgM IgM antibodies immunoassay independent Informed Maternal maternity hospitals Migration multicentre Naso-pharyngeal swab naso-pharyngeal swabs Nasopharyngeal swab nasopharyngeal swabs Neonate observational study Participants passive immunity platform positive Pregnancy pregnant women Prevalence prospective observational study Prospective Study provided raising remained responses Result RNA Roche RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV2 serological assays serological assessment serological evidence serological response serological test seropositive serum serum sample Seven symptomatic the antibody response Transplacental umbilical Umbilical cord Viral Viral RNA was measured was obtained was performed women written consent
[DOI] 10.1371/journal.pone.0253090 PMC 바로가기 [Article Type] Observational Study

Is the Immunization of Pregnant Women against COVID-19 Justified?

Review

Published on 2021-08-302022-10-28
Journal: Vaccines [Category] COVID-19,

[키워드] Administered age antibody breastmilk carried children clinical trial coronavirus disease COVID-19 COVID-19 vaccine disease Efficacy evaluate fetal Follow-up immune response immunization increased risk Infants Infection Infectious disease initiated knowledge lactating women Maternal maternal immunization morbidity and mortality mother Mother-to-child transmission mRNA COVID-19 vaccine mRNA vaccine Neonates nonpregnant not different offer offspring passive immunity Placenta platform Pregnancy pregnant pregnant women preventive measure PROTECT Sample size severe disease subjects to define Tolerability transferred Vaccine virus variant women
[DOI] 10.3390/vaccines9090970 PMC 바로가기 [Article Type] Review

SARS-CoV-2 Antibodies Detected in Mother’s Milk Post-Vaccination

백신 접종 후 모유에서 SARS-CoV-2 항체 검출

Article

Published on 2021-08-012022-09-11
Journal: Journal of human lactation : official journal of I [Category] SARS, 치료기술,

[키워드] acute respiratory syndrome coronavirus analyzed Breastfeeding Clinicians collected coronavirus 2 Course COVID-19 COVID-19 vaccines death determine dose Efficacy effort elevated human milk IgA IgA antibodies IgA antibody IgG immunization Immunoglobulin immunoglobulins individual Infant Infants initial lactating lactating women lactation longitudinal cohort study Maternal maternally-acquired immunity milk Moderna mother s milk pandemic passive immunity patients Pfizer Pfizer-BioNTech potential transmission pre-vaccination Protective provided receive Research respiratory Sample SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine second dose second dose of vaccine Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly Spread timepoints Trial vaccination Vaccine vaccine dose virus writing
[DOI] 10.1177/08903344211030168 PMC 바로가기 [Article Type] Article