Differences and Similarities Among COVID-19 Patients Treated in Seven ICUs in Three Countries Within One Region: An Observational Cohort StudyObservational Study Published on 2022-04-012022-10-05 Journal: Critical Care Medicine [Category] 임상, [키워드] Admission admitted to ICU age Analysis applied approval assessment Belgium Characteristics chronic Clinical characteristics Comorbidities complications coronavirus disease COVID-19 COVID-19 patient criteria Descriptive statistics Diagnosis difference disease severity driver European failure female Frequency Genetic Germany healthcare Healthcare system ICU independent interfere International Laboratory Logistic regression measurement Mortality mortality rate Netherlands Observational cohort study organ support outcome pandemic Patient patient group performed Physiology retrieved Sex significantly Support supported Therapies therapy variance Variation [DOI] 10.1097/CCM.0000000000005314 PMC 바로가기 [Article Type] Observational Study
Micro-Fourier-transform infrared reflectance spectroscopy as tool for probing IgG glycosylation in COVID-19 patientsCOVID-19 환자에서 IgG 글리코 실화를 조사하기위한 도구로서 마이크로 푸리에 변환 적외선 반사 분광 광경.Article Published on 2022-03-112022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] Activation Adaptive immune response Anti-spike antibody Antibody Response Asymptomatic Biophotonics Blood Brazil carbonyl chemiluminescent immunoassay CLIA correlation COVID-19 COVID-19 patient COVID-19 patients Critically ill Cutoff detection rate diagnosed with COVID-19 Diagnostic markers disease dissemination ELISA excessive inflammatory response extension glycosylation healthcare worker healthy helping IgA IgG IgG antibodies IgG1 IgM immune response Immunoglobulin indicated individual individuals with COVID-19 Infection marker Mild Optics and photonics Other photonics outcome Patient patients Physiology positive probe Quantitative RBD reported SARS-CoV-2 SARS-CoV-2 viral load serum sample serum samples severity signal specificity Viral Viral antigen Volunteer worsening [DOI] 10.1038/s41598-022-08156-6 PMC 바로가기 [Article Type] Article
Pathophysiology of coronavirus-19 disease acute lung injuryArticle Published on 2022-02-132023-06-15 Journal: Current opinion in critical care [Category] COVID19(2023년), MERS, SARS, [키워드] Coronavirus-19 disease Critical care Physiology respiratory Respiratory distress syndrome SARS-CoV-2 [DOI] 10.1097/MCC.0000000000000911 PMC 바로가기
Systems analysis shows that thermodynamic physiological and pharmacological fundamentals drive COVID‐19 and response to treatmentReview Published on 2022-02-012023-06-14 Journal: Pharmacology Research & Perspectives [Category] COVID19(2023년), MERS, SARS, [키워드] ACE2 affinity complex systems COVID‐19 Dissociation constant Gibbs free energy Innate immunity Kinetics law of mass action MERS pandemic Pharmacology Physiology renin angiotensin system SARS‐CoV‐1 SARS‐CoV‐2 Thermodynamics tropism variants virus [DOI] 10.1002/prp2.922 PMC 바로가기 [Article Type] Review
Face Masks Use and Its Role in Restraining the Spread of COVID-19 Pandemic in Saudi Arabia: Knowledge, Attitude, and Practices Based Cross-Sectional StudyObservational Study Published on 2022-01-242022-10-04 Journal: Frontiers in Public Health [Category] SARS, 임상, [키워드] age Attitude college Community conducted COVID-19 COVID-19 pandemic Department Effectiveness face Face mask Face masks females Government King knowledge Likert scale male Mask Medicine MOST participant Participants Physiology positive attitude Practice predominant question questionnaire reported Restraining role SARS-CoV-2 Saudi Arabia social media platform Spread university was collected [DOI] 10.3389/fpubh.2021.818520 PMC 바로가기 [Article Type] Observational Study
Arrhythmogenic mechanisms of interleukin-6 combination with hydroxychloroquine and azithromycin in inflammatory diseases염증성 질환에서 하이드 록시 클로로 퀴인 및 아지트로 마이신과의 인터루킨 -6 조합의 부정맥 메커니즘Article Published on 2022-01-202022-09-01 Journal: Scientific Reports [Category] 진단, 치료제, [키워드] Abnormalities abnormality action potential addition Administered analyzed arrhythmia Arrhythmias asystole Azithromycin bradycardia cardiac injury Cardiology caused characterized Combination COVID-19 Critical cytokine Cytokine storm disease drug drug combination Drug discovery Electrocardiograms electrocardiographic elevated examined greater HCQ heart rate Hydroxychloroquine IL-6 IL-6 receptor immunology In-vitro Inflammation inflammatory disease Inflammatory diseases Injury interleukin-6 management mechanism Medical research Mild mild to moderate moderate monoclonal antibody pharmacotherapy Physiology PIGS prolongation QTc QTC prolongation reducing reduction in risk selective selective inhibition TCZ therapy Tocilizumab [DOI] 10.1038/s41598-022-04852-5 PMC 바로가기 [Article Type] Article
Overexpression of the SARS-CoV-2 receptor angiotensin converting enzyme 2 in cardiomyocytes of failing heartsArticle Published on 2022-01-192022-10-04 Journal: Scientific Reports [Category] 바이오마커, [키워드] ACE2 ACE2 expression ACE2 receptor Biochemistry Biomarkers Biotechnology Cardiology cardiovascular comorbidity Cell Biology dependent on disease Diseases Donor Endothelial cell endothelial cells enzyme expressed expression fibroblast fibroblasts healthy donor heart heart failure hearts immunohistochemistry immunology in both groups infect cells Medical research Molecular biology Molecular medicine myocarditis organ outcome Patient Physiology proteomics Quantitative receptor risk RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus subpopulation the SARS-CoV-2 tissue ventricular was measured was used [DOI] 10.1038/s41598-022-04956-y PMC 바로가기 [Article Type] Article
Better COVID-19 Intensive Care Unit survival in females, independent of age, disease severity, comorbidities, and treatmentArticle Published on 2022-01-142022-10-04 Journal: Scientific Reports [Category] 임상, 치료법, [키워드] 95%CI added adjusted administration Admission age APACHE II APACHE II score association Belgium Better chronic Comorbidities comparable comprehensive analysis coronavirus 2 country COVID-19 disease course disease severity Diseases Factor female females Germany ICU independent intensive care unit investigated less Logistic regression male mechanism Medical research Model Modification Mortality multicenter Netherlands no effect obese obesity Observational cohort study Odds ratio organ support other variables pandemic Pathogenesis Patient patients patients with SARS-CoV-2 Physiology Pneumonia prognostic random intercept respiratory Risk factors SARS-CoV-2 SARS-CoV-2 patient Seven Sex smoking survival Therapeutic approach therapy Treatment was used [DOI] 10.1038/s41598-021-04531-x PMC 바로가기 [Article Type] Article
Comparative Evaluation of the Prognosis of Septic Shock Patients from Before to After the Onset of the COVID-19 Pandemic: A Retrospective Single-Center Clinical AnalysisArticle Published on 2022-01-132022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] 95% CI Analysis clinical Comparative coronavirus coronavirus disease COVID-19 COVID-19 pandemic Department determine Duration Emergency emergency department Final Hospitalization intensive care investigated Isolation mechanical ventilation medical record Mortality mortality rate Onset outcome pandemic Patient Physiology protocol risk factor score Sepsis septic Septic shock significant difference South Korea statistically significant System [DOI] 10.3390/jpm12010103 PMC 바로가기 [Article Type] Article
All-digital training course in neurophysiology: lessons learned from the COVID-19 pandemicResearch Published on 2022-01-032022-10-28 Journal: BMC Medical Education [Category] Coronavirus, SARS, [키워드] all-digital training course, laboratory Analysis block blocks Cohort cohorts comparable conducted Contact Course courses COVID-19 pandemic described Efficiency implementation inherent investigated knowledge lab lack measure occur offered online questionnaire pandemic Pandemics Participants Physiology Prospective Study question remote response Result social contact social distancing statistical analysis synchronous Tolerance transfer Virtual [DOI] 10.1186/s12909-021-03062-3 PMC 바로가기 [Article Type] Research