Silymarin/curcumin loaded albumin nanoparticles coated by chitosan as muco-inhalable delivery system observing anti-inflammatory and anti COVID-19 characterizations in oleic acid triggered lung injury and in vitro COVID-19 experiment키토산으로 코팅된 실리마린/커큐민 로딩 알부민 나노입자는 올레산 유발 폐 손상 및 시험관 내 COVID-19 실험에서 항염증 및 항 COVID-19 특성을 관찰하는 점막 흡입성 전달 시스템Article Published on 2022-02-152022-09-11 Journal: International journal of biological macromolecules [Category] 비임상, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome albumin alveolar Anti-inflammatory anti-viral activity assembly bovine bovine serum albumin BSA C-reactive protein can be used candidate chitosan coated coronavirus COVID-19 edema Efficacy ENhance experiment Health health problem hyaline membrane hyaline membranes hyperplasia identify in vitro infected patient infected patients Inflammation inflammatory process interleukin interleukin-6 Lung injury lung lesion lung lesions moment Mucoadhesive. oleic acid overcome Pneumonia Polymer Protein reduction in respiratory respiratory distress Respiratory distress syndrome septal serum albumin silymarin syndrome treated Treatment treatment of COVID-19 triggered virus [DOI] 10.1016/j.ijbiomac.2021.12.073 PMC 바로가기 [Article Type] Article
Antiviral/antibacterial biodegradable cellulose nonwovens as environmentally friendly and bioprotective materials with potential to minimize microplastic pollution항바이러스/항균 생분해성 셀룰로오스 부직포는 미세플라스틱 오염을 최소화할 수 있는 환경 친화적이고 생물 보호적인 소재입니다.Article Published on 2022-02-152022-09-11 Journal: Journal of hazardous materials [Category] COVID19(2023년), SARS, 치료제, [키워드] activity Antibacterial Antiviral Aquatic ecosystems biodegradability Cellulose component coronavirus SARS-CoV-2 COVID-19 COVID-19 crisis crisis demonstrated dominant Environment equipment Face mask Face masks grafting guanidine hydrophobicity lack Mask Microstructure Neomycin neomycin sulfate Personal protective equipment Polymer Polypropylene PPE Protective raised reagent robust SARS-CoV-2 sulfate textiles Textiles. virucidal [DOI] 10.1016/j.jhazmat.2021.127391 PMC 바로가기 [Article Type] Article
Development of polypyrrole (nano)structures decorated with gold nanoparticles toward immunosensing for COVID-19 serological diagnosisResearch article Published on 2022-02-072022-10-05 Journal: Materials Today. Chemistry [Category] 치료기술, [키워드] acute respiratory syndrome anti-SARS-CoV-2 Antibody concentrations biosensor characterized clinical sample concerning contribute coronavirus COVID-19 Detection limit development Diagnosis electrical Gold nanoparticle Gold nanoparticles Human humans immunosensor Impedimetric biosensor infection control linear Microscopy MONITOR monoclonal antibodies monoclonal antibody morphology Polymer Polypyrrole modified electrode Polypyrrole nanotubes positive Protein reported SARS-CoV-2 Seroconversion serological serum was used [DOI] 10.1016/j.mtchem.2022.100817 [Article Type] Research article
Synthetic molecule libraries for nucleic acid delivery: Design parameters in cationic/ionizable lipids and polymersReview article Published on 2022-02-012022-10-05 Journal: Drug metabolism and pharmacokinetics [Category] 비임상, [키워드] biodegradability Cationic lipid Cationic polymer described develop drug Extracellular facilitate hydrophobicity in vitro in vivo Lipid Liver disease mechanism nanomedicine nanoparticle Nuclease nucleic acid Nucleic acid delivery Other parameter Polymer PROTECT recent Structure synthetic translated Treatment virus infection [DOI] 10.1016/j.dmpk.2021.100428 [Article Type] Review article
Inhibition of Escherichia Virus MS2, Surrogate of SARS-CoV-2, via Essential Oils-Loaded Electrospun Fibrous Mats: Increasing the Multifunctionality of Antivirus Protection MasksArticle Published on 2022-01-272022-10-28 Journal: Pharmaceutics [Category] COVID-19, [키워드] affected antimicrobial Antiviral antiviral essential oils average Combination combinations Concentration COVID-19 demonstrated effective electrospun fibers Escherichia Escherichia coli Essential examined exhibiting Face masks fiber Gas Chromatography-Mass Spectrometry Increasing infiltration inhibit inhibition Log reduction Mask Masks Mat measure MS2 overcome penetration physisorption versus blending Polymer prevented processed protection reduce SARS-CoV-2 SARS-CoV-2 surrogate SARS-CoV-2 transmission Scent selected surrogate viability viral inhibitors viral particle virucidal virus was used [DOI] 10.3390/pharmaceutics14020303 PMC 바로가기 [Article Type] Article
Clinical efficacy of iodine complex in SARS-CoV-2-infected patients with mild to moderate symptoms: study protocol for a randomized controlled trial경증에서 중등도의 증상을 보이는 SARS-CoV-2 감염 환자에서 요오드 복합체의 임상 효능: 무작위 대조 시험을 위한 연구 프로토콜Update Published on 2022-01-192022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] adaptive addition alleviate analyzed Arm benefit both groups caused Chest clinic clinical clinical trial collected Combination complex Computed tomography conducted coronavirus disease Coronavirus disease 2019 Coronavirus-2 country COVID-19 COVID-19 patient COVID-19 patients doctor Efficacy High-resolution Hospitalization HRCT implication IMPROVE in both groups Intervention Iodine lower mortality Mild mild to moderate mild to moderate symptoms moderate Mortality Novel coronavirus pandemic parallel group parameter Patient Placebo placebo-controlled Polymer questionnaire radiological improvement Randomized controlled trial randomized trial receive reduction in respiratory respiratory syndrome coronavirus RT-PCR Sample size SARS-CoV-2 SARS-CoV-2-infected patient SAS version 9.4 severe respiratory syndrome socioeconomic status standard care Study protocol symptomatic Symptoms syrup Treatment treatment of COVID-19 Trial Trial registration Viral Viral load viral load reduction with COVID-19 written consent [DOI] 10.1186/s13063-021-05848-8 PMC 바로가기 [Article Type] Update
An ultrasensitive molecularly imprinted polymer-based electrochemical sensor for the determination of SARS-CoV-2-RBD by using macroporous gold screen-printed electrode거대 다공성 금 스크린 인쇄 전극을 사용한 SARS-CoV-2-RBD 측정을 위한 초고감도 분자 각인 고분자 기반 전기화학 센서Article Published on 2022-01-152022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alkaline ATR Concentration coronavirus Electrochemical sensor electrode electron microscope electron transfer Ethanol exhibited ferrocyanide gold limit of detection Macroporous gold screen-printed electrode Microscope MIP Molecularly imprinted polymer Polymer polymer matrix Receptor-binding domain Saliva SARS-CoV-2-RBD scanning electron microscope SEM sensitivity severe acute respiratory syndrome Coronavirus stability Template the receptor-binding domain was used X-ray spectroscopy [DOI] 10.1016/j.bios.2021.113729 PMC 바로가기 [Article Type] Article
Face mask-A potential source of phthalate exposure for human안면 마스크-인간의 프탈레이트 노출 가능성Article Published on 2022-01-152022-09-11 Journal: Journal of hazardous materials [Category] SARS, 치료기술, [키워드] Adults carcinogenic collected coronavirus disease Coronavirus disease 2019 Effect Estimated Estimated daily intake exhibited exposure to face Face mask Face masks Human humans indicated knowledge Mask Masks moderate Occurrence phthalate Phthalate exposure Polymer polymers ranged risk Risk assessment Safe wearing mask wearing masks [DOI] 10.1016/j.jhazmat.2021.126848 PMC 바로가기 [Article Type] Article
High throughput molecularly imprinted polymers based electrochemical nanosensors for point-of-care diagnostics of COVID-19Short communication Published on 2022-01-012022-10-05 Journal: Materials Letters [Category] 진단, [키워드] Biorecognition elements costly COVID-19 COVID-19 pandemic diagnostic diagnostics early diagnosis electrochemical sensors element elements fabrication Infectious disease Molecularly imprinted polymer offer point-of-care Polymer SARS-CoV-2 specificity time-consuming [DOI] 10.1016/j.matlet.2021.130898 [Article Type] Short communication
Thermosensitive Poly(DHSe/PEG/PPG Urethane)-Based Hydrogel Extended Remdesivir Application in Ophthalmic MedicationArticle Published on 2021-12-272022-10-28 Journal: Pharmaceutics [Category] COVID-19, [키워드] acute respiratory syndrome application caused characterized conjunctival Corneal coronavirus coronavirus disease COVID-19 dose epithelial cells evaluated exhibited Extended eyes Final gel gelling glycol hydrogel in vivo indicated Infection lack Microscopy Novel coronavirus ocular ocular irritation ocular retention ophthalmic drug delivery outbreak penetration Polymer polymerized PPG provided RDV Remdesivir SARS-CoV-2 Spread temperature thermosensitive hydrogel Tolerance Transmission was used [DOI] 10.3390/pharmaceutics14010050 PMC 바로가기 [Article Type] Article