Evaluation of the performance of 25 SARS-CoV-2 serological rapid diagnostic tests using a reference panel of plasma specimens at the Uganda Virus Research Institute우간다 바이러스 연구소에서 혈장 표본의 참조 패널을 사용한 25개의 SARS-CoV-2 혈청학적 신속 진단 테스트의 성능 평가Article Published on 2021-11-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgM antibodies antibody Antibody testing Boson collected coronavirus COVID-19 detect diagnostic diagnostic test diagnostic tests Epidemiology evaluated IgG antibodies IgM and IgG IgM antibodies IgM/IgG performance performed plasma positive positive patient positive patients Rapid Rapid diagnostic test RDT RDTs reference panel respiratory SARS-CoV-2 SARS-CoV-2 PCR sensitivity Sensitivity and specificity serological serological reference panel. Serological testing severe acute respiratory syndrome Coronavirus specific antibodies specificity specimen Standard Q Test Uganda virus widespread [DOI] 10.1016/j.ijid.2021.09.020 PMC 바로가기 [Article Type] Article
A rapid and low-cost protocol for the detection of B.1.1.7 lineage of SARS-CoV-2 by using SYBR Green-based RT-qPCRSYBR Green 기반 RT-qPCR을 사용하여 SARS-CoV-2의 B.1.1.7 계통을 탐지하기 위한 빠르고 저렴한 프로토콜Article Published on 2021-11-012022-09-11 Journal: Molecular biology reports [Category] SARS, 변종, 치료기술, 치료제, [키워드] Applied Biosystem B.1.1.7 B.1.1.7 lineage coronavirus COVID-19 COVID-19 pandemic develop Diagnosis exhibit False negative false negative result false negative results identify Lineage molecular test Mutation N gene new SARS-CoV-2 NSP6 ORF1 ORF1ab other variants pandemic Patient positive positive patients primer primer set primer sets protocol reproductive RT-PCR RT-PCR assay RT-qPCR S-gene SARS CoV SARS CoV-2 SARS-CoV-2 Sequencing SYBR Green SYBR Green-based RT-PCR TaqPath targets Thermo Fisher Scientific Transmissibility United Kingdom USA variant VoC VOC (202012/01). [DOI] 10.1007/s11033-021-06717-y PMC 바로가기 [Article Type] Article
External validation of Machine Learning models for COVID-19 detection based on Complete Blood CountResearch Published on 2021-10-232022-10-31 Journal: Health Information Science and Systems [Category] COVID-19, [키워드] affected applicability applied AUC average calibrated calibration CBC clinician collected comparable complete blood count count COVID-19 COVID-19 diagnosis COVID-19 patients dataset datasets develop Diagnosis diagnostic error rate External external validation false-negative rate faster help hematological parameter hospital Italy less machine learning ML model ML models positive positive patients reported Result routine rRT-PCR RT-PCR shortage of reagents SVM was performed [DOI] 10.1007/s13755-021-00167-3 PMC 바로가기 [Article Type] Research
Administration of Monoclonal Antibody for COVID-19 in Patient Homes환자 가정에서 COVID-19에 대한 단클론항체 투여Research Published on 2021-10-142022-09-12 Journal: JAMA Network Open [Category] MERS, SARS, 진단, [키워드] cohort study COVID-19 home monoclonal antibody treatment Monoclonal antibody treatments outcome Patient positive patients Program [DOI] 10.1001/jamanetworkopen.2021.29388 PMC 바로가기 [Article Type] Research
Chronic dysglycemia and risk of SARS‐CoV‐2 associated respiratory failure in hospitalized patientsObservational Study Published on 2021-10-112022-10-04 Journal: Acta Anaesthesiologica Scandinavica [Category] MERS, SARS, 임상, [키워드] 95% CI acute respiratory syndrome adjusted Admission age Analysis association body mass index category chronic Cohort coronavirus diabete diabetes dysglycemia Hospitalization Hospitalized hospitalized patient increased risk Karolinska University Hospital multivariable logistic regression Patient patients positive patient positive patients Respiratory failure Result retrospective risk SARS‐CoV‐2 severe Covid‐19 Sex Stage [DOI] 10.1111/aas.13982 PMC 바로가기 [Article Type] Observational Study
Association between chronic hepatitis B infection and COVID-19 outcomes: A Korean nationwide cohort study만성 B 형 간염 감염과 COVID-19 결과의 연관성 : 한국 전국 코호트 연구Research Article Published on 2021-10-052022-09-10 Journal: PLoS ONE [Category] B형 간염, MERS, 치료제, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted odds ratio Antiviral antiviral agent Antiviral agents Antiviral treatment association CHB chronic hepatitis Chronic Hepatitis B Clinical outcome cohort study Coinfection collected Comorbidities Comorbidity Control coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 negative COVID-19 positive patient database disease severity Endpoint entecavir greater HBV Health Insurance Infection infection rate infection rates insurance Korean lead National Health Insurance negative controls Patient positive positive patients primary endpoints proportion random reduced respiratory Result risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity SARS-CoV-2 test selected service severe acute respiratory syndrome Coronavirus statistically susceptibility target population tenofovir test result tested Treatment with infection worse prognosis [DOI] 10.1371/journal.pone.0258229 PMC 바로가기 [Article Type] Research Article
Aerosol SARS-CoV-2 in hospitals and long-term care homes during the COVID-19 pandemicCovid-19 Pandemic 동안 병원 및 장기 치료 가정에서 에어로졸 SARS-COV-2Research Article Published on 2021-09-302022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, 치료제, [키워드] aerosol Care close contact collected Concentration COVID-19 pandemic examined experiment gelatin hospital hospital ward ICU in viral indicated information Long-term care micrometer Multiplex PCR N protein no significant difference not recovered outbreak Outbreaks Particle positive positive patient positive patients quantified Result risk RNA RNA sample RNA samples Sample SARS-CoV-2 SARS-CoV-2 virus stomatitis TCID the patient Transmission Ultrasonic vesicular stomatitis vesicular stomatitis virus viability Viral viral genome Viral RNA virus VSV with COVID-19 [DOI] 10.1371/journal.pone.0258151 PMC 바로가기 [Article Type] Research Article
COVID-19 myocarditis: quantitative analysis of the inflammatory infiltrate and a proposed mechanismCOVID-19 심근염 : 염증 침윤 및 제안 된 메커니즘의 정량적 분석Article Published on 2021-09-012022-08-31 Journal: Cardiovascular pathology : the official journal of [Category] MERS, SARS, 바이오마커, [키워드] (hypertension age appear Autopsy autopsy, myocarditis, heart, inflammation, macrophages. cardiovascular disease cardiovascular system CD4+ CD68 CD68 cells CD68+ cell CD68+ cells CD8+ cell CD8+ cells Cell Cohort cohort of patient cohorts Comorbidities Comorbidity COVID-19 COVID-19 positive patient described diabetes diagnosed disease distribution heart hearts Histopathology hypertension incidence infiltrative Inflammation Inflammatory inflammatory cell Lineage macrophages matched control mechanism Monocytes myocarditis obesity positive patients Post-mortem Quantitative analysis SARS-CoV-2 severe disease significant effect significant increase skewed skewed distribution study cohort Type II Diabetes viral myocarditis while [DOI] 10.1016/j.carpath.2021.107361 PMC 바로가기 [Article Type] Article
Are the Portable Air Cleaners (PAC) really effective to terminate airborne SARS-CoV-2?휴대용 공기 청정기(PAC)가 공기 중 SARS-CoV-2를 종식시키는 데 정말 효과적입니까?Article Published on 2021-09-012022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, [키워드] aerosol Aerosols air and surface Airborne SARS-CoV-2 analyzed Chain Reaction Cleaner collected Contamination coronavirus Device displaying effective Effectiveness Efficiency gelatin HEPA HEPA filter Households limitation Particles polymerase chain polymerase chain reaction Portable Air Cleaners positive positive patient positive patients Real-Time Reverse Transcription Polymerase Chain Reaction removal reverse transcription RNA RT-PCR SARS CoV SARS CoV-2 SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RNA detection SARS-CoV-2 virus Spread surfaces swab sample swab samples swabs transmission of SARS-CoV-2 Ventilation Viral particles virus was performed [DOI] 10.1016/j.scitotenv.2021.147300 PMC 바로가기 [Article Type] Article
SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19SARS-COV-2 스파이크 단백질 S1은 섬유소 분해에 내성이있는 피브린 (OGEN)을 유도합니다.Diagnostics & Biomarkers Published on 2021-08-272022-09-01 Journal: Bioscience Reports [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus added Blood blood flow change characterized circulation complement contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients COVID-19 positive patient electron and fluorescence microscopy electron microscopy FIBRIN Fibrin(ogen) fibrinolysis fluorescence microscopy healthy hypercoagulability Hypercoagulation impairment implication induce Infection interfere lung Lungs mass spectrometry Microclot observation ogen Pathologies patients plasma plasma sample plasma samples Platelet platelet-poor plasma Platelets positive patients Protein prothrombin respiratory S1 subunit SARS-CoV-2 spike protein severe acute respiratory syndrome coronavirus 2 Spike protein spike protein S1 Spike protein Sa Treatment trypsinization [DOI] 10.1042/BSR20210611 PMC 바로가기 [Article Type] Diagnostics & Biomarkers