Postinfection – Page 4 – Communicable Diseases Research

A clinical case definition of post-COVID-19 condition by a Delphi consensus

Review article

Published on 2021-12-212022-10-05
Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), SARS, 임상,

Durability of SARS-CoV-2-Specific T-Cell Responses at 12 Months Postinfection

Article

Published on 2021-12-152022-11-15
Journal: The Journal of Infectious Diseases [Category] SARS, 바이오마커, 진단, 치료기술,

[키워드] 12 months acute illness acute respiratory syndrome age antibody CD4 T cell Cellular immune response cellular response clinical outcomes coronavirus coronavirus disease COVID-19 Cytotoxic T cell cytotoxicity detectable disease disease severity Durability ENhance flow cytometry Frequency identify Immunity induce Infection influence intracellular cytokine staining investigated magnitude memory memory T cell Month multisite natural infection participant Peripheral blood Phenotypes polyfunctionality Postinfection prospective cohort study representing response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody SARS-CoV-2-specific T cell severe disease T cell therapeutic interventions
[DOI] 10.1093/infdis/jiab543 PMC 바로가기

An immunodominant NP 105–113 -B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Article

Published on 2021-12-012022-10-04
Journal: Nature Immunology [Category] Fulltext, SARS, 유전자 메커니즘, 임상, 치료기술, 치료법,

[키워드] Antiviral antiviral efficacy association Beta CD8 clone Control convalescent correlated COVID-19 disease COVID-19 severity CTL CTLs cytotoxic T lymphocyte Delta demonstrated disease severity dominant functional Gamma immune memory immunodominant Immunological memory in vitro Inclusion Infection less performed Postinfection precursors preserved progression reduced SARS-COV-2 infection SARS-CoV-2-infected individuals Sequencing severe COVID-19 disease single-cell T cell T cell receptor T cell response targets the SARS-CoV-2 Transcriptome Vaccine Vaccine design variants Victoria viral infection viral replication with mild disease
[DOI] 10.1038/s41590-021-01084-z PMC 바로가기 [Article Type] Article

Pro-inflammatory CXCL-10, TNF-α, IL-1β, and IL-6: biomarkers of SARS-CoV-2 infection

전염증성 CXCL-10, TNF-α, IL-1β 및 IL-6: SARS-CoV-2 감염의 바이오마커

Article

Published on 2021-12-012022-09-11
Journal: Archives of Virology [Category] 바이오마커,

[키워드] antiviral cytokine antiviral cytokines Asymptomatic Biomarker Biomarkers categories category caused chemokine chemokines city clinical manifestation clinical manifestations controls CXCL-10 CXCL10 cytokine cytokine production Cytokines disease early phase except for excessive cytokine production Factor Hospitalized IFN-γ IL-12 IL-17 IL-1β IL-4 IL-6 immune system India individual infected patients Infection infiltration inflammatory cells investigated Level Luminex platform mildly symptomatic patient mildly symptomatic patients morbidity morbidity and mortality no difference Novel coronavirus novel coronavirus SARS-CoV-2 outcome pandemic of COVID-19 Patient Plasma cytokine Postinfection pro-inflammatory cytokine pro-inflammatory cytokines recovered patient recovered patients reduced SARS-COV-2 infection SARS-CoV-2 patient SARS-CoV-2 patients SARS-CoV-2-infected patient significantly higher significantly lower symptomatic the patient TNF-α uninfected control VEGF Viral viral infections virus replication
[DOI] 10.1007/s00705-021-05247-z PMC 바로가기 [Article Type] Article

Immunologic memory to SARS-CoV-2 in convalescent COVID-19 patients at 1 year postinfection

감염 후 1년에 회복 중인 COVID-19 환자의 SARS-CoV-2에 대한 면역학적 기억

Article

Published on 2021-12-012022-09-12
Journal: The Journal of Allergy and Clinical Immunology [Category] SARS, 진단,

[키워드] acute respiratory syndrome anti-receptor-binding domain antibody CD4 CD4(+) T-cell responses Cell cellular response convalescent COVID-19 patient convalescent patient Convalescent patients coronavirus coronavirus disease correlation COVID-19 Critical CTLA-4 cytokine dysfunction evaluate follow-up time groups humoral immune immune memory Immunologic memory increased expression marker moderate multifunctional NAb Neutralizing antibodies neutralizing antibody observé positive rate positively correlated Postinfection Prevalence produced proportion protective immunity reached recruited Reinfection SARS-CoV-2 SARS-CoV-2-specific T cell severity statistical statistical significance Support T cell T-cell TIGIT understanding vaccination were assessed with COVID-19
[DOI] 10.1016/j.jaci.2021.09.008 PMC 바로가기 [Article Type] Article

Transparent Polymeric Formulations Effective against SARS-CoV-2 Infection

SARS-CoV-2 감염에 효과적인 투명한 고분자 제제

Article

Published on 2021-11-242022-09-11
Journal: ACS applied materials & interfaces [Category] SARS, 치료제,

[키워드] 229E alternative Antibacterial antibacterial activity antimicrobial agent antimicrobial agents Antiviral antiviral activity antiviral property approaches backbone Bacteria benzalkonium Candida albican Candida albicans candidate Cell CFU class Compound compounds Contact contaminated surface contaminated surfaces coronavirus decrease droplet droplets EMA European Medicines Agency evaluated Formulation fungal gram Gram-negative bacteria Gram-positive bacteria growth increasingly inhibit Ion Particle Polymer polymers polystyrene sulfonate Postinfection product reduction SARS-CoV-2 SARS-CoV-2 coronavirus SARS-COV-2 infection SARS-CoV-2 virus silver Spread sulfonate target cell tested the SARS-CoV-2 virus Transmission transmitted variety virucidal virus
[DOI] 10.1021/acsami.1c10404 PMC 바로가기 [Article Type] Article

Humoral response to SARS‐CoV‐2 and seasonal coronaviruses in COVID‐19 patients

COVID-19 환자의 SARS-CoV-2 및 계절성 코로나바이러스에 대한 체액 반응

Research Article

Published on 2021-11-082022-09-10
Journal: Journal of medical virology [Category] MERS, SARS, 치료법,

[키워드] 229E acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody antibody levels Antibody Response Antibody responses association both groups Cohort control group convalescent plasma coronavirus Coronaviruses correlated correlation COVID COVID‐19 patient Definition disease severity Donor elevated Evidence evidence of HCoV HCoV 229E high responder human coronavirus human coronaviruses humoral humoral immune response Humoral response immunoassay in both group individual Infection lead levels of antibodies levels of antibody no evidence of nucleocapsid Postinfection predisposition Prevalence Protein respiratory SARS‐CoV‐2 SARS‐CoV‐2 antibodies SARS‐CoV‐2 antibody SARS‐CoV‐2 seasonal coronavirus seasonal coronaviruses severe acute respiratory syndrome Coronavirus significantly symptom onset tested while
[DOI] 10.1002/jmv.27427 PMC 바로가기 [Article Type] Research Article

Tracking the Transcription Kinetic of SARS-CoV-2 in Human Cells by Reverse Transcription-Droplet Digital PCR

Article

Published on 2021-10-022022-10-28
Journal: Pathogens [Category] COVID-19,

Symptoms and Health Outcomes Among Survivors of COVID-19 Infection 1 Year After Discharge From Hospitals in Wuhan, China

Research

Published on 2021-09-292022-10-29
Journal: JAMA Network Open [Category] COVID-19, SARS,

[키워드] 95% CI age Analysis Anxiety Cerebrovascular disease Chest chronic obstructive cohort study conducted consecutive sample COPD COVID-19 declined defined discharge discharged discharged patients disease Dyspnea eligibility enrolled evaluate exposure fatigue female finding Follow-up had more Health higher risk hospital hospital discharge Hospital stay Hospitalization Hospitalized hospitals Huoshenshan Hospital identify Importance independent risk factor Infection IQR measure median men multicenter cohort study myalgia objective Odds ratio outcome participant participated Patient patients with COVID-19 Point Postinfection pulmonary disease questionnaire Regression model Relevance reported Result retrospective risk factor Risk factors screened setting severe disease Sex survivor sweating Symptom symptom burden Symptoms symptoms of COVID-19 the median Tongji Hospital was performed were excluded were used with COVID-19 World Health Organization Wuhan, China Year
[DOI] 10.1001/jamanetworkopen.2021.27403 PMC 바로가기 [Article Type] Research

Sera Neutralizing Activities Against Severe Acute Respiratory Syndrome Coronavirus 2 and Multiple Variants 6 Months After Hospitalization for Coronavirus Disease 2019

중증 급성 호흡기 증후군 코로나바이러스 2 및 다중 변이체에 대한 혈청 중화 활성 코로나바이러스 질병 2019로 입원 후 6개월

Article

Published on 2021-09-152022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 진단, 치료법,

[키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Admission Against anti-S Anti-spike antibodies antibody B.1.1.7 B.1.351 B.1.351 variant characterized collected coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 D614G effective Efficiency Evolution experiment Hospitalized humoral Humoral response IgG IgG level IgG levels Immunoglobulin Immunoglobulin G initial intensive care unit intensive care units invasive ventilation Level marker Month Multiple neutralization Neutralizing activity neutralizing capacity neutralizing effect occur P.1 variant P.1 variants Patient patients hospitalized performed Postinfection Prospective Study quantified Quantitative respiratory SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sera serological Serological assay serological assays severe acute respiratory syndrome Coronavirus severity significantly sustained tested the patient variant with COVID-19
[DOI] 10.1093/cid/ciab308 PMC 바로가기 [Article Type] Article