Rapid transition between SARS-CoV-2 variants of concern Delta and Omicron detected by monitoring municipal wastewater from three Canadian cities캐나다 3개 도시의 도시 폐수를 모니터링하여 SARS-CoV-2 변종 우려 델타와 오마이크론 간의 신속한 전환 감지Article Published on 2022-10-012022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Affect BA.1 BA.2 biases Chemical Chemical tracer collected Concentration correlation Delta demography determined by dominant Factor Government greater incidence of COVID-19 individuals introduced Lineage lineages local outbreak local outbreaks Migration MONITOR monitoring omicron pandemic plant Population Population size Prairie predominant proportion qPCR Rapid Raw influent Regulation RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 variant Surveillance surveillance data Treatment variant Variant of concerns variants variants of concern viral loads VoC VOCs was used wastewater whole-genome sequencing [DOI] 10.1016/j.scitotenv.2022.156741 PMC 바로가기 [Article Type] Article
Effectiveness of a Second COVID-19 Vaccine Booster Dose Against Infection, Hospitalization, or Death Among Nursing Home Residents – 19 States, March 29-July 25, 2022Article Published on 2022-09-302022-11-16 Journal: Morbidity and Mortality Weekly Report [Category] SARS, 변종, [키워드] Against Analysis B.1.1.529 booster booster dose booster doses cause collected Committee Community COVID-19 COVID-19 infection COVID-19 vaccine death deaths dose Effectiveness Endpoint evaluated facility Follow-up home Hospitalization Immunocompromised monovalent vaccine morbidity and mortality mRNA Nursing omicron outcome outcomes Practice predominant Prevent provided resident routine care SARS-CoV-2 second severe COVID-19 vaccination Vaccine variant variants virus with COVID-19 [DOI] 10.15585/mmwr.mm7139a2 PMC 바로가기
Shedding of infectious SARS-CoV-2 despite vaccinationArticle Published on 2022-09-302022-11-15 Journal: PLoS Pathogens [Category] SARS, 변종, 치료기술, [키워드] caused concern COVID-19 COVID-19 case cycle threshold Delta delta variant determine Immune escape individual individuals Infectious virus Laboratory Mutation nasal swab no significant effect North America predominant RT-PCR SARS-CoV-2 SARS-CoV-2 vaccine Sex shedding specimen subset tested Testing vaccinated individual vaccination Vaccine [DOI] 10.1371/journal.ppat.1010876 PMC 바로가기
Predictive Value of Isolated Symptoms for Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children Tested During Peak Circulation of the Delta VariantArticle Published on 2022-09-302022-11-16 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, [키워드] acute respiratory syndrome Asymptomatic calculated children Clinical characteristics close contact confidence interval coronavirus coronavirus 2 Coronavirus disease 2019 cough COVID-19 Delta delta variant determine evaluated Fever group headache highest individual symptoms Isolated likelihood molecular Negative predictive value not significantly different Odds ratio offered participant Participants peak Poisson model positive positive COVID-19 Positive predictive value PPV Predictive predominant presenting Prevalence respiratory SARS-CoV-2 SARS-CoV-2 test saturated School sensitivity significantly more sore throat specificity Symptom symptomatic Symptoms tested Testing value [DOI] 10.1093/cid/ciac112 PMC 바로가기
Protection against omicron (B.1.1.529) BA.2 reinfection conferred by primary omicron BA.1 or pre-omicron SARS-CoV-2 infection among health-care workers with and without mRNA vaccination: a test-negative case-control study주요 오미크론 BA.1 또는 오미크론 이전 SARS-CoV-2 감염에 의해 부여된 오미크론 (B.1.1.529) BA.2 재감염에 대한 보호: mRNA 백신 접종 여부에 따른 의료 종사자를 대상으로 한 검사 음성 사례 대조 연구Article Published on 2022-09-212022-10-06 Journal: The Lancet. Infectious Diseases [Category] SARS, 진단, [키워드] 95% CI B.1.1.529 benefit case-control study conducted Control database determine diagnosed dose doses Effect Genetic greater health-care Immunity inclusion criteria Infection infection risk Laboratory likelihood Lineage mRNA mRNA vaccination mRNA vaccine negative test nucleic acid amplification Older omicron paucity of data Positive test positive test result predominant Primary infection protection Quebec, Canada reduction in Regression model Reinfection risk reduction SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test service study period tested vaccination vaccine dose variant variants was increased [DOI] 10.1016/S1473-3099(22)00578-3 PMC 바로가기 [Article Type] Article
A self-assembled trimeric protein vaccine induces protective immunity against Omicron variantArticle Published on 2022-09-172022-11-15 Journal: Nature Communications [Category] SARS, 변종, 진단, [키워드] addition animal models B.1.1.529 Breakthrough infection circulating clinical trials Complete Delta delta variant dose elicited humoral immune response Immune escape immune response in vivo induce L452R Live virus mice mRNA vaccines neutralizing antibody non-human primates omicron predominant prime-boost regimen protective immunity Protein RBD resulting SARS-CoV-2 SARS-CoV-2 S2 SARS-CoV-2 vaccine SARS-CoV-2 variant sequence subunit surpassed sustained T cell T478K Transmissibility trimer trimeric vaccinated individuals vaccination Vaccine vaccine candidate variant variants [DOI] 10.1038/s41467-022-33209-9 PMC 바로가기
SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patternsArticle Published on 2022-09-142022-10-06 Journal: Cell Host & Microbe [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] antibody antigenic BA.2.12.1 BA.4 BA.5 convalescent COVID-19 Critical effective strategy favor identify immune Immune escape inactive monoclonal antibody MOST Neutralizing Neutralizing antibodies neutralizing antibody omicron polyclonal predominant provide reduction in resistance SARS-CoV-2 sensitivity sera serum sublineages. susceptibility Treatment vaccinated individual vaccinee variants viral evolution [DOI] 10.1016/j.chom.2022.07.002 PMC 바로가기 [Article Type] Article
The COVID-19 pandemic and Alzheimer’s disease: mutual risks and mechanismsArticle Published on 2022-09-112022-11-16 Journal: Translational Neurodegeneration [Category] SARS, 유전자 메커니즘, [키워드] ACE2 ACE2 receptor acute respiratory syndrome age Alzheimer’s disease angiotensin-converting enzyme 2 ApoE approach association caused cell membranes Central nervous system clinical outcomes CNS coronavirus Coronavirus disease 2019 COVID-19 COVID-19 pandemic disease Diseases dysfunction expressed Genotype host cell increasingly individual key factor life-threatening mechanism Neuroinflammation neurological predominant recent receptor risk risk factor SARS-CoV-2 SARS-COV-2 infection susceptible the spike protein those with comorbidities [DOI] 10.1186/s40035-022-00316-y PMC 바로가기
Population level SARS-CoV-2 fecal shedding rates determined via wastewater-based epidemiology폐수 기반 역학을 통해 결정된 인구 수준 SARS-CoV-2 배설물 배출율Article Published on 2022-09-102022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, [키워드] average Community Community demographics Concentration condition COVID-19 COVID-19 disease COVID-19 pandemic delta variant demographics disease Epidemiology Ethnicity Factor fecal Fecal shedding feces finding in some infected individuals involved log median age occurred Outbreaks pandemic Population predominant provided Rate remained SARS-CoV-2 SARS-CoV-2 RNA significantly increased unique vaccination variant variants virus concentration Virus concentrations wastewater Wastewater-based epidemiology [DOI] 10.1016/j.scitotenv.2022.156535 PMC 바로가기 [Article Type] Article
Genomic surveillance of SARS-CoV-2 Omicron variants on a university campusArticle Published on 2022-09-062022-11-15 Journal: Nature Communications [Category] SARS, 변종, 유전자 메커니즘, 진단, [키워드] conducted Cycle threshold value Delta delta variant demonstrated Genome genomic Genomic surveillance greater individual Mask mandates Measures median novel omicron pandemic positive predominant Public health responses reproductive SARS-CoV-2 sequenced Sequencing surveillance data symptomatic infection tested the SARS-CoV-2 university vaccination variant viral strain whole genome [DOI] 10.1038/s41467-022-32786-z PMC 바로가기