Incorporating oral PrEP into standard prevention services for South African women: a nested interrupted time-series study남아프리카 여성을위한 표준 예방 서비스에 구강 준비를 통합 : 중첩 된 시계열 연구Articles Published on 2021-06-112022-09-06 Journal: The Lancet. HIV [Category] Communicable Disease, [키워드] 95% CI acquisition adjusted African AIDS Analysis assigned clinical trial clinical trials Contraception contraceptive contraceptive method contraceptives cooperation country decrease determine development eligible Emergency experiment finding Follow-up foundation funding HIV HIV infection HIV prevention incidence incidence rate Intervention Kenya Medical Research Council Melinda Gate Melinda Gates natural experiment nine not used outcome participant plan Population PrEP President Prophylaxis Providing Randomly rate ratio receive Registered relief reported sensitivity analysis Seroconversion South South Africa study visit Swedish These data Trial trials United Nation United Nations United State United States women [DOI] 10.1016/S2352-3018(21)00048-5 PMC 바로가기 [Article Type] Articles
Pathogenesis-based preexposure prophylaxis associated with a low risk of SARS-CoV-2 infection in healthcare workers at a designated COVID-19 hospital: a pilot studyResearch Article Published on 2021-06-072022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] ACM adverse event collected Combination conducted coronavirus disease COVID-19 defined disease effective Efficacy evaluate FIVE Frequency function functions Genetic HCW HCWs healthcare worker hospital Immunological test incidence individual Inosine ISRCTN knowledge laboratory-confirmed less low-dose medication Mild occurred Open-label outcome participant Pathogenesis pilot study positive Potassium preexposure prophylaxis PrEP Prevent Reactions Registered Research Result retrospective risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity significantly single-arm single-center study study period supplementary material Support treating COVID-19 patients treatments for COVID-19 [DOI] 10.1186/s12879-021-06241-1 PMC 바로가기 [Article Type] Research Article
Chemoprophylaxis trial designs in epidemics: insights from a systematic review of COVID-19 study registrations전염병에 대한 화학 예방 실험 설계: COVID-19 연구 등록에 대한 체계적인 검토에서 얻은 통찰력Review Published on 2021-05-292022-09-10 Journal: Trials [Category] SARS, 변종, 치료기술, 치료제, [키워드] adaptive adaptive design Adaptive platform trial Adults alignment Analysis attack rate attack rates Care Chain Reaction Chemoprophylaxis Chloroquine clinically collaboration component control group coronavirus country COVID-19 COVID-19 vaccines database detect effect size effective Efficacy Efficacy and safety eligibility enrolment Epidemic Epidemics epidemiologically Evidence evidence of exit feasible feature focus followed by General population generate healthcare worker Healthcare workers Hydroxychloroquine implementation Infection Infectious disease Infectious diseases information International IQR less Long-term care Lopinavir Lopinavir/ritonavir mechanism median median size novel vaccines offer Older older adult Older adults pandemic patients polymerase chain reaction Polymerase chain reaction testing PrEP Primary outcome Prophylaxis protocol provided public health randomised Rapid recruitment Registered Repurposed drug Repurposed drugs required Result review Ritonavir robust safety analysis SARS-CoV-2 screened searched Serological testing study population supplementary material Supporting systematic review target population Trial trial infrastructure Trial registration trials utility Vaccine Vaccines virus variants was used were assessed widespread without symptom [DOI] 10.1186/s13063-021-05323-4 PMC 바로가기 [Article Type] Review
Facilitators and barriers of 2-1-1 HIV pre-exposure prophylaxis2-1-1 HIV 노출 전 예방의 촉진제 및 장벽Research Article Published on 2021-05-202022-09-10 Journal: PLoS ONE [Category] 치료제, [키워드] 2-1-1 affected challenge conducted cross-sectional cross-sectional study desire dose doses effective facilitator facilitators healthcare Healthcare provider healthcare providers HIV HIV prevention include individual Laboratory testing less medication men National pandemic participant participated Pharmacy preference PrEP processing Prophylaxis question receiving reduce reductions reductions in reported researcher resulting SARS-CoV-2 pandemic Sex Side effect Side effects switching the SARS-CoV-2 understanding [DOI] 10.1371/journal.pone.0251917 PMC 바로가기 [Article Type] Research Article
A collision of crises: Addressing an HIV outbreak among people who inject drugs in the midst of COVID-19위기의 충돌: COVID-19의 한가운데 약물을 주사하는 사람들 사이의 HIV 발생 해결Article Published on 2021-05-012022-09-11 Journal: Journal of substance abuse treatment [Category] 치료제, [키워드] Abstract COVID-19 disorders drug HIV HIV pre-exposure prophylaxis (PrEP) HIV prevention Injection drug use outbreak PrEP Prophylaxis substance substance use disorders [DOI] 10.1016/j.jsat.2021.108280 PMC 바로가기 [Article Type] Article
Changes in Sexual Behavior, PrEP Adherence, and Access to Sexual Health Services Because of the COVID-19 Pandemic Among a Cohort of PrEP-Using MSM in the SouthCOVID-19 전염병으로 인한 성 행동, PrEP 준수 및 성 건강 서비스 접근의 변화, 남부의 PrEP 사용 MSM 코호트Article Published on 2021-05-012022-09-11 Journal: Journal of acquired immune deficiency syndromes (1 [Category] SARS, 치료제, [키워드] access ad hoc adherence Administered Anal anal sex analyzed Behavior change changed changes in Cohort conducted consequence coronavirus disease Coronavirus disease 2019 COVID-19 cross-sectional analysis decrease disease document Ensuring examined followed by Health services HIV HIV testing impacted imperative linear male men oral sex pandemic participant PrEP Prophylaxis quarter reduced regression models risk service Sex sexual sexually transmitted disease South transmitted United State United States utilization [DOI] 10.1097/QAI.0000000000002640 PMC 바로가기 [Article Type] Article
Evaluation of mobile real-time polymerase chain reaction tests for the detection of severe acute respiratory syndrome coronavirus 2중증급성호흡기증후군 코로나바이러스 2 검출을 위한 모바일 실시간 중합효소연쇄반응 검사 평가Article Published on 2021-04-302022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 치료기술, 치료제, [키워드] 5′ UTR acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Bacterial pathogens Biomonitoring can be used Care caused Cell culture clinical sample clinical samples Combination coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-reactivity detect Diagnosis diarrhea epidemic diarrhea evaluated gastroenteritis Genes genetic material handling Health Health care human respiratory virus IBV inactivated independent Infectious Bronchitis Virus Laboratory limit lysis buffer MERS MERS-CoV Microbiology middle Middle Eastern respiratory syndrome coronavirus molecular assays Molecular biology operator ORF1ab pandemic Pathogens PEDV platform point-of-care polymerase chain PrEP reaction Real-time PCR respiratory respiratory syndrome coronavirus respiratory viruses RNA room temperature Safe Sample SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 test SARS-CoV-2-infected hamsters severe acute respiratory syndrome Coronavirus Swab swabs target targets temperature test results Transmission untranslated region Viral viral infection virus viruses [DOI] 10.1038/s41598-021-88625-6 PMC 바로가기 [Article Type] Article
The potential effect of COVID-19-related disruptions on HIV incidence and HIV-related mortality among men who have sex with men in the USA: a modelling study미국에서 남성과 성관계를 가진 남성의 HIV 발병률 및 HIV 관련 사망률에 대한 COVID-19 관련 혼란의 잠재적 영향: 모델링 연구Article Published on 2021-04-012022-09-11 Journal: The Lancet. HIV [Category] 치료제, [키워드] absence accompanied Antiretroviral therapy ART available data Baltimore calibrated Care changes changes in COVID-19 COVID-19 pandemic credible interval cumulative death declined Disruption Effect HIV HIV infection HIV testing incidence increase main analysis maintain maintaining median men Mortality offset pandemic predict predicted PrEP Prophylaxis reduce reduced reduction in reductions reductions in reported Sex Support the median Transmission model USA [DOI] 10.1016/S2352-3018(21)00022-9 PMC 바로가기 [Article Type] Article
Prophylaxis for COVID-19: a systematic reviewCOVID-19 예방: 체계적인 검토Article Published on 2021-04-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 비임상, 임상, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 animals antibodies breath candidate Candidates clinical clinical trial registry Committee controlled trials coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cross-sectional studies cross-sectional study database eligibility criteria evaluated Evidence FIVE HCQ Human Hydroxychloroquine identify inclusion criteria journal landscape majority medRxiv Novel coronavirus novel coronavirus disease other compounds outcome populations PrEP Prophylactic Prophylaxis Randomized control trials Randomized controlled trial RCT RCTs registries registry reported respiratory SARS-CoV-2 systematic review Treatment Vaccine Vaccines Vitamin vitamins while [DOI] 10.1016/j.cmi.2021.01.013 PMC 바로가기 [Article Type] Article
Whole-genome sequencing of SARS-CoV-2 reveals the detection of G614 variant in PakistanSARS-CoV-2의 전체 게놈 시퀀싱은 파키스탄에서 G614 변이체의 검출을 보여줍니다Research Article Published on 2021-03-232022-08-13 Journal: PLoS ONE [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amino acid Analysis aspartic acid characteristic China clade coronavirus D614G D614G mutation Diego Evolution FIVE G614 variant genetic diversity Genome Genome sequences genomic GISAID glycine highlight Illumina Inc. India lead library Missense Mutation mutations NCBI Oman oropharyngeal swab oropharyngeal swabs pandemic Patient Phylogenetic analysis positive PrEP prevalent real-time RT-PCR Region respiratory reveal RNA SARS-CoV-2 SARS-CoV-2 strain selected sequence sequences Sequencing severe acute respiratory syndrome Coronavirus shown Slovakia Spike protein Spread strain Strains submitted United States virus Virus evolution viruses was performed whole genome Whole genome sequencing whole-genome whole-genome sequencing [DOI] 10.1371/journal.pone.0248371 PMC 바로가기 [Article Type] Research Article